Eamonn Martin Quigley, MD

David M. Underwood Chair of Medicine in Digestive Disorders, Department of Medicine
Professor of Medicine, Institute for Academic Medicine
Director, Lynda K. and David M. Underwood Center for Digestive Disorders
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Eamonn M. M. Quigley, past president of the American College of Gastroenterology and the World Gastroenterology Organization, joined the faculty at Houston Methodist Hospital as head of its Gastroenterology and Hepatology division in 2013.

Prior to his move to Houston, Quigley was professor of medicine and human physiology and a principal investigator at the Alimentary Pharmabiotic Centre at the National University of Ireland in Cork. He is internationally known for his research on gastrointestinal motility disorders, primarily irritable bowel syndrome (IBS); gastroesophageal reflux disease (GERD); neurogastroenterology (the relationship between the central nervous system and the gut); the gut microbiome and probiotics in health and disease. A highlight of his ongoing research includes how bacteria in the digestive tract play a major role in pulling nutrients from food to nourish the body, as well as participating in protecting the body from disease.

IBS is the most common, chronic medical condition in the United States. Approximately 40 percent of those with IBS have symptoms severe or frequent enough to disrupt their daily lives. While the cause of IBS has not been clearly identified, Quigley’s clinical research suggests that an alteration of the normal gut bacteria flora may be a cause. His research team is working toward developing new biomarkers for IBS which would eventually lead to the development of new treatments. Quigley’s clinical interests focus on the use of probiotics for the treatment of IBS.

He has published more than 800 peer-reviewed articles, reviews, editorials, book chapters and case reports, mostly in the areas of gut motility, functional gastrointestinal disorders, and GERD. Quigley has received numerous international honors and awards. He served as Editor-in-Chief of the American Journal of Gastroenterology from 1997 to 2003.

Quigley received his medical degree from  University College Cork in Cork, Ireland; completed internal medicine residency in Glasgow, Scotland; and did GI fellowship training at the Mayo Clinic and the University of Manchester in England.  He served as the Chief of Gastroenterology at the University of Nebraska from 1991 to 1998 and as Dean of the Medical School in Cork, Ireland from 2000 to 2007.

Description of Research

Some of his pioneering research over the past several decades has included how the function of the gut is affected in a variety of diseases and conditions, including chronic liver disease, high-dose chemoradiotherapy, intestinal failure and transplantation, and Parkinson’s disease.

Areas Of Expertise

Gastroesophageal Reflux Esophageal disorders/dysphagia Gastrointestinal motility disorders Functional GI disorders Irritable bowel syndrome Gastroparesis Constipation Diarrheal disorders Celiac disease Intestinal & colonic disorders Inflammatory bowel disease/colitis/Crohn's disease General gastroenterology EGD and colonoscopy Capsule endoscopy
Education & Training

Clinical Fellowship, University of Manchester
Residency, Western Infirmary & Associates Hospital
Internship, St. Finbarr's Hospital
MD, National University of Ireland;
Publications

The Gut Microbiome Influences Responses to Programmed Death 1 Therapy in Chinese Lung Cancer Patients — the Benefits of Diversity
Bernicker, EH & Quigley, EM 2019, Journal of Thoracic Oncology, vol. 14, no. 8, pp. 1319-1322. https://doi.org/10.1016/j.jtho.2019.05.016

Overlapping irritable bowel syndrome and inflammatory bowel disease
Gajula, P & Quigley, EM 2019, Minerva Gastroenterologica e Dietologica, vol. 65, no. 2, pp. 107-115. https://doi.org/10.23736/S1121-421X.19.02559-5

Editorial: Lactobacillus GG for diarrhoea in children—reports of its demise have been premature!
Quigley, EM 2019, Alimentary Pharmacology and Therapeutics, vol. 49, no. 12, pp. 1533-1534. https://doi.org/10.1111/apt.15288

Letter: meta-analysis of prebiotics, probiotics, synbiotics and antibiotics in IBS. Authors’ reply
Ford, AC, Harris, LA, Lacy, BE, Quigley, EM & Moayyedi, P 2019, Alimentary Pharmacology and Therapeutics, vol. 49, no. 9, pp. 1254-1255. https://doi.org/10.1111/apt.15234

Editorial: Thought for food: diet and gut health
Quigley, EM 2019, Current opinion in gastroenterology, vol. 35, no. 2, pp. 99-100. https://doi.org/10.1097/MOG.0000000000000505

Irritable bowel syndrome and colonic diverticular disease: overlapping symptoms and overlapping therapeutic approaches
Alamo, RZ & Quigley, EM 2019, Current opinion in gastroenterology, vol. 35, no. 1, pp. 27-33. https://doi.org/10.1097/MOG.0000000000000499

Editorial: From eosinophils to serrated adenomas and beyond: late breaking news from the dark continent
Quigley, EM 2019, Current opinion in gastroenterology, vol. 35, no. 1, pp. 25-26. https://doi.org/10.1097/MOG.0000000000000496

Editorial introductions
Kelly, CP, Wilcox, MH & Quigley, EM 2019, Current opinion in gastroenterology, vol. 35, no. 1, pp. v-vi. https://doi.org/10.1097/MOG.0000000000000500

Prebiotics and Probiotics in Digestive Health
Quigley, EM 2019, Clinical Gastroenterology and Hepatology, vol. 17, no. 2, pp. 333-344. https://doi.org/10.1016/j.cgh.2018.09.028

The Spectrum of Small Intestinal Bacterial Overgrowth (SIBO)
Quigley, EM 2019, Current Gastroenterology Reports, vol. 21, no. 1, 3. https://doi.org/10.1007/s11894-019-0671-z

Systematic review with meta-analysis: cholecystectomy for biliary dyskinesia—what can the gallbladder ejection fraction tell us?
Gudsoorkar, VS, Oglat, A, Jain, A, Raza, A & Quigley, EM 2019, Alimentary Pharmacology and Therapeutics. https://doi.org/10.1111/apt.15128

Antibiotics and probiotics in inflammatory bowel disease: When to use them?
Abraham, BP & Quigley, EM 2019, Frontline Gastroenterology. https://doi.org/10.1136/flgastro-2018-101057

Efficacy of pharmacological therapies in patients with IBS with diarrhoea or mixed stool pattern: Systematic review and network meta-analysis
Black, CJ, Burr, NE, Camilleri, M, Earnest, DL, Quigley, EM, Moayyedi, P, Houghton, LA & Ford, AC 2019, Gut. https://doi.org/10.1136/gutjnl-2018-318160

Symptoms and the small intestinal microbiome — the unknown explored
Quigley, EM 2019, Nature Reviews Gastroenterology and Hepatology. https://doi.org/10.1038/s41575-019-0171-5

The diagnosis of small intestinal bacterial overgrowth: Two steps forward, one step backwards?
Di Stefano, M & Quigley, EM 2018, Neurogastroenterology and Motility, vol. 30, no. 11, e13494. https://doi.org/10.1111/nmo.13494

Highlights of the updated evidence-based IBS treatment monograph
Quigley, EM 2018, Gastroenterology and Hepatology, vol. 14, no. 11, pp. 665-667.

Reply
Quigley, EM, Koduru, P & Irani, M 2018, Clinical Gastroenterology and Hepatology, vol. 16, no. 10. https://doi.org/10.1016/j.cgh.2018.05.053

‘Brain Fogginess’ and D-Lactic Acidosis: Probiotics Are Not the Cause
Quigley, EM, Pot, B & Sanders, ME 2018, Clinical and Translational Gastroenterology, vol. 9, no. 9, 187. https://doi.org/10.1038/s41424-018-0057-9

A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPs Diet in Treating Symptoms of Irritable Bowel Syndrome
Dionne, J, Ford, AC, Yuan, Y, Chey, WD, Lacy, BE, Saito, YA, Quigley, EMM & Moayyedi, P 2018, The American journal of gastroenterology. https://doi.org/10.1038/s41395-018-0195-4

American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome
for the ACG Task Force on Management of Irritable Bowel Syndrome 2018, American Journal of Gastroenterology, pp. 1-18. https://doi.org/10.1038/s41395-018-0084-x

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