Eamonn Martin Quigley, MD

David M. Underwood Chair of Medicine in Digestive Disorders, Department of Medicine
Professor of Medicine, Academic Institute
Director, Lynda K. and David M. Underwood Center for Digestive Disorders
Houston Methodist
Weill Cornell Medical College


Dr. Eamonn M. M. Quigley, past president of the American College of Gastroenterology and the World Gastroenterology Organization, joined the faculty at Houston Methodist Hospital as head of its Gastroenterology and Hepatology division in 2013.

Prior to his move to Houston, Quigley was professor of medicine and human physiology and a principal investigator at the Alimentary Pharmabiotic Centre at the National University of Ireland in Cork. He is internationally known for his research on gastrointestinal motility disorders, primarily irritable bowel syndrome (IBS); gastroesophageal reflux disease (GERD); neurogastroenterology (the relationship between the central nervous system and the gut); the gut microbiome and probiotics in health and disease. A highlight of his ongoing research includes how bacteria in the digestive tract play a major role in pulling nutrients from food to nourish the body, as well as participating in protecting the body from disease.

IBS is the most common, chronic medical condition in the United States. Approximately 40 percent of those with IBS have symptoms severe or frequent enough to disrupt their daily lives. While the cause of IBS has not been clearly identified, Quigley’s clinical research suggests that an alteration of the normal gut bacteria flora may be a cause. His research team is working toward developing new biomarkers for IBS which would eventually lead to the development of new treatments. Quigley’s clinical interests focus on the use of probiotics for the treatment of IBS.

He has published more than 800 peer-reviewed articles, reviews, editorials, book chapters and case reports, mostly in the areas of gut motility, functional gastrointestinal disorders, and GERD. Quigley has received numerous international honors and awards. He served as Editor-in-Chief of the American Journal of Gastroenterology from 1997 to 2003.

Quigley received his medical degree from  University College Cork in Cork, Ireland; completed internal medicine residency in Glasgow, Scotland; and did GI fellowship training at the Mayo Clinic and the University of Manchester in England.  He served as the Chief of Gastroenterology at the University of Nebraska from 1991 to 1998 and as Dean of the Medical School in Cork, Ireland from 2000 to 2007.

Description of Research

Some of his pioneering research over the past several decades has included how the function of the gut is affected in a variety of diseases and conditions, including chronic liver disease, high-dose chemoradiotherapy, intestinal failure and transplantation, and Parkinson’s disease.

Areas Of Expertise

Gastroesophageal Reflux Esophageal disorders/dysphagia Gastrointestinal motility disorders Functional GI disorders Irritable bowel syndrome Gastroparesis Constipation Diarrheal disorders Celiac disease Intestinal & colonic disorders Inflammatory bowel disease/colitis/Crohn's disease General gastroenterology EGD and colonoscopy Capsule endoscopy
Education & Training

Clinical Fellowship, University of Manchester
Residency, Western Infirmary & Associates Hospital
Internship, St. Finbarr's Hospital
MD, National University of Ireland;

Small Intestinal Bacterial Overgrowth
Bushyhead, D & Quigley, EM 2021, , Gastroenterology Clinics of North America, vol. 50, no. 2, pp. 463-474. https://doi.org/10.1016/j.gtc.2021.02.008

Low FODMAP (fermentable oligo-, di-, monosaccharides, and polyol) diet goes global
Quigley, EMM 2021, , American Journal of Clinical Nutrition, vol. 113, no. 6, pp. 1394-1395. https://doi.org/10.1093/ajcn/nqab084

Nutrition in health and gastrointestinal disease: From molecule to clinic
Quigley, EMM 2021, , Current opinion in gastroenterology, vol. 37, no. 2, pp. 112-113. https://doi.org/10.1097/MOG.0000000000000711

The patient with irritable bowel syndrome-type symptoms: when to investigate and how?
Quigley, EMM 2021, , Current opinion in gastroenterology, vol. 37, no. 1, pp. 39-43. https://doi.org/10.1097/MOG.0000000000000686

Editorial: Colon cancer detection and prevention in the age of COVID-19
Quigley, EMM 2021, , Current opinion in gastroenterology, vol. 37, no. 1, pp. 37-38. https://doi.org/10.1097/MOG.0000000000000697

Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment
Corsetti, M, Brown, S, Chiarioni, G, Dimidi, E, Dudding, T, Emmanuel, A, Fox, M, Ford, AC, Giordano, P, Grossi, U, Henderson, M, Knowles, CH, O’Connell, PR, Quigley, EMM, Simren, M, Spiller, R, Whelan, K, Whitehead, WE, Williams, AB & Scott, SM 2021, , Neurogastroenterology and Motility, vol. 33, no. 7, e14070. https://doi.org/10.1111/nmo.14070

Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study
Sperber, AD, Bangdiwala, SI, Drossman, DA, Ghoshal, UC, Simren, M, Tack, J, Whitehead, WE, Dumitrascu, DL, Fang, X, Fukudo, S, Kellow, J, Okeke, E, Quigley, EMM, Schmulson, M, Whorwell, P, Archampong, T, Adibi, P, Andresen, V, Benninga, MA, Bonaz, B, Bor, S, Fernandez, LB, Choi, SC, Corazziari, ES, Francisconi, C, Hani, A, Lazebnik, L, Lee, YY, Mulak, A, Rahman, MM, Santos, J, Setshedi, M, Syam, AF, Vanner, S, Wong, RK, Lopez-Colombo, A, Costa, V, Dickman, R, Kanazawa, M, Keshteli, AH, Khatun, R, Maleki, I, Poitras, P, Pratap, N, Stefanyuk, O, Thomson, S, Zeevenhooven, J & Palsson, OS 2021, , Gastroenterology, vol. 160, no. 1, pp. 99-114.e3. https://doi.org/10.1053/j.gastro.2020.04.014

The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
Salminen, S, Collado, MC, Endo, A, Hill, C, Lebeer, S, Quigley, EMM, Sanders, ME, Shamir, R, Swann, JR, Szajewska, H & Vinderola, G 2021, , Nature Reviews Gastroenterology and Hepatology. https://doi.org/10.1038/s41575-021-00440-6

Publisher Correction: The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics (Nature Reviews Gastroenterology & Hepatology, (2021), 10.1038/s41575-021-00440-6)
Salminen, S, Collado, MC, Endo, A, Hill, C, Lebeer, S, Quigley, EMM, Sanders, ME, Shamir, R, Swann, JR, Szajewska, H & Vinderola, G 2021, , Nature Reviews Gastroenterology and Hepatology. https://doi.org/10.1038/s41575-021-00481-x

Inflammatory Bowel Disease and Atherosclerotic Cardiovascular Disease: JACC Review Topic of the Week
Cainzos-Achirica, M, Glassner, K, Zawahir, HS, Dey, AK, Agrawal, T, Quigley, EMM, Abraham, BP, Acquah, I, Yahya, T, Mehta, NN & Nasir, K 2020, , Journal of the American College of Cardiology, vol. 76, no. 24, pp. 2895-2905. https://doi.org/10.1016/j.jacc.2020.10.027

Editorial: the microbiome, aspirin and colorectal cancer
O’Grady, J & Quigley, EMM 2020, , Alimentary Pharmacology and Therapeutics, vol. 52, no. 11-12, pp. 1740-1741. https://doi.org/10.1111/apt.16071

Effects of the vibrating capsule on colonic circadian rhythm and bowel symptoms in chronic idiopathic constipation
Rao, SSC, Lembo, A, Chey, WD, Friedenberg, K & Quigley, EMM 2020, , Neurogastroenterology and Motility, vol. 32, no. 11, e13890. https://doi.org/10.1111/nmo.13890

The probiotic Bifidobacterium in the management of Coronavirus: A theoretical basis
Bozkurt, HS & Quigley, EMM 2020, , International Journal of Immunopathology and Pharmacology, vol. 34. https://doi.org/10.1177/2058738420961304

AGA Clinical Practice Update on Small Intestinal Bacterial Overgrowth: Expert Review
Quigley, EMM, Murray, JA & Pimentel, M 2020, , Gastroenterology, vol. 159, no. 4, pp. 1526-1532. https://doi.org/10.1053/j.gastro.2020.06.090

Abnormal balloon expulsion test in patients with fecal incontinence
Neshatian, L, Fosso, CL & Quigley, EM 2020, , Journal of Gastrointestinal and Liver Diseases, vol. 29, no. 3, pp. 345-351. https://doi.org/10.15403/jgld-2273

Efficacy of psychological therapies for irritable bowel syndrome: Systematic review and network meta-analysis
Black, CJ, Thakur, ER, Houghton, LA, Quigley, EMM, Moayyedi, P & Ford, AC 2020, , Gut, vol. 69, no. 8, pp. 1441-1451. https://doi.org/10.1136/gutjnl-2020-321191

“It ain't over … till it's over!” Risk-mitigation strategies for patients with gastrointestinal diseases in the aftermath of the COVID-19 pandemic
Holtmann, G, Quigley, EM, Shah, A, Camilleri, M, Tan, VPY, Gwee, KA, Sugano, K, Sollano, JD, Fock, KM, Ghoshal, UC, Chen, M, Dignass, A & Cohen, H 2020, , Journal of Gastroenterology and Hepatology (Australia), vol. 35, no. 7, pp. 1117-1123. https://doi.org/10.1111/jgh.15133

Peppermint Oil in Irritable Bowel Syndrome
Black, CJ, Moayyedi, P, Quigley, EMM & Ford, AC 2020, , Gastroenterology, vol. 159, no. 1, pp. 395-396. https://doi.org/10.1053/j.gastro.2019.09.055

Erratum: Antibiotics and probiotics in inflammatory bowel disease: When to use them? (Frontline Gastroenterology (2020) 11 (62–69) DOI: 10.1136/flgastro-2018-101057)
Abraham, B & Quigley, EMM 2020, , Frontline Gastroenterology, vol. 11, no. 3, pp. E1. https://doi.org/10.1136/flgastro-2018-101057corr1

Irritable bowel syndrome in celiac disease - relationships to celiac disease antibodies and levels of pro-inflammatory cytokines
Olano, C, López, V, Freire, T, Rodríguez, X, Pontet, Y, Alemán, A, Rodríguez, N, Rovira, L, Trucco, E, Osinaga, E, Cohen, H & Quigley, EM 2020, , Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú, vol. 40, no. 2, pp. 127-135.