Dimitry Sayenko

Dimitry Sayenko, MD, PhD

Paula and Joseph C. “Rusty” Walter III Associate Professor in Neuromodulation, Center for Translational Neural Prosthetics and Interfaces
Associate Professor of Neurosurgery , Academic Institute
Associate Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Neuromodulation & Recovery Lab


dgsayenko@houstonmethodist.org
Description of Research

Physiology, Neuroscience, Motor Control, Balance, Postural Control, Locomotion, Spinal Cord, Spinal Cord Injury, Stroke, Spinal Cord Stimulation, Neuromodulation

Areas Of Expertise

Stroke Neuroscience Neuromodulation Spinal Cord Injury Physiology Spinal cord Spinal Cord Stimulation Motor Control Postural Control Locomotion
Publications

Impact of different ground-based microgravity models on human sensorimotor system
Saveko, A, Bekreneva, M, Ponomarev, I, Zelenskaya, I, Riabova, A, Shigueva, T, Kitov, V, Abu Sheli, N, Nosikova, I, Rukavishnikov, I, Sayenko, D & Tomilovskaya, E 2023, , Frontiers in Physiology, vol. 14, 1085545. https://doi.org/10.3389/fphys.2023.1085545

Minimal handgrip force is needed for transcutaneous electrical stimulation to improve hand functions of patients with severe spinal cord injury
Huang, R, Nikooyan, AA, Moore, LD, Zdunowski, S, Morikawa, E, Sierro, T, Sayenko, D, Gad, P, Homsey, T, Le, T, Madhavan, MA, Abdelshahid, M, Abdelshahid, M, Zhou, Y, Nuwer, MR, Sarrafzadeh, M, Edgerton, VR, Leiter, JC & Lu, DC 2022, , Scientific Reports, vol. 12, no. 1, 7733. https://doi.org/10.1038/s41598-022-11306-5

Cervical transcutaneous spinal stimulation for spinal motor mapping
Oh, J, Steele, AG, Varghese, B, Martin, CA, Scheffler, MS, Markley, RL, Lo, YK & Sayenko, DG 2022, , iScience, vol. 25, no. 10, 105037. https://doi.org/10.1016/j.isci.2022.105037

Effects of transcutaneous spinal stimulation on spatiotemporal cortical activation patterns: A proof-of-concept EEG study
Steele, AG, Manson, GA, Horner, PJ, Sayenko, DG & Contreras-Vidal, JL 2022, , Journal of neural engineering, vol. 19, no. 4, 046001. https://doi.org/10.1088/1741-2552/ac7b4b

Measuring Torque Production with a Robotic Exoskeleton during Cervical Transcutaneous Spinal Stimulation
Mahan, E, Dunkelberger, N, Oh, J, Simmons, M, Varghese, B, Sayenko, D & OMalley, M 2022, , Paper presented at 2022 International Conference on Rehabilitation Robotics (ICORR), 7/25/22.

Transcutaneous spinal stimulation alters cortical and subcortical activation patterns during mimicked-standing: A proof-of-concept fMRI study
Manson, G, Atkinson, DA, Shi, Z, Sheynin, J, Karmonik, C, Markley, RL & Sayenko, DG 2022, , Neuroimage: Reports, vol. 2, no. 2, 100090. https://doi.org/10.1016/j.ynirp.2022.100090

Characterization of interlimb interaction via transcutaneous spinal stimulation of cervical and lumbar spinal enlargements
Atkinson, DA, Steele, AG, Manson, GA, Sheynin, J, Oh, J, Gerasimenko, YP & Sayenko, DG 2022, , Journal of Neurophysiology, vol. 127, no. 4, pp. 1075-1085. https://doi.org/10.1152/jn.00456.2021

Transcutaneous spinal stimulation alters cortical and subcortical activation patterns during mimicked-standing: A proof-of-concept fMRI study
Manson, GA, Atkinson, DA, Shi, Z, Sheynin, J, Karmonik, C, Markley, R & Sayenko, D 2022, , Neuroimage: Reports.

Neuromodulation and restoration of motor responses after severe spinal cord injury
Sayenko, DG, Cerrel Bazo, HA, Horner, PJ & Taccola, G 2022, . in Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury. Elsevier, pp. 51-63. https://doi.org/10.1016/B978-0-12-822427-4.00005-8

Measuring Torque Production with a Robotic Exoskeleton during Cervical Transcutaneous Spinal Stimulation
Mahan, E, Dunkelberger, N, Oh, J, Simmons, M, Varghese, B, Sayenko, D & OMalley, MK 2022, . in 2022 International Conference on Rehabilitation Robotics, ICORR 2022. IEEE International Conference on Rehabilitation Robotics, vol. 2022-July, Institute of Electrical and Electronics Engineers Inc. 2022 International Conference on Rehabilitation Robotics, ICORR 2022, Rotterdam, Netherlands, 7/25/22. https://doi.org/10.1109/ICORR55369.2022.9896477

Characterization of spinal sensorimotor network using transcutaneous spinal stimulation during voluntary movement preparation and performance
Steele, AG, Atkinson, DA, Varghese, B, Oh, J, Markley, RL & Sayenko, DG 2021, , Journal of Clinical Medicine, vol. 10, no. 24, 5958. https://doi.org/10.3390/jcm10245958

Voluntary modulation of evoked responses generated by epidural and transcutaneous spinal stimulation in humans with spinal cord injury
Calvert, JS, Gill, ML, Linde, MB, Veith, DD, Thoreson, AR, Lopez, C, Lee, KH, Gerasimenko, YP, Edgerton, VR, Lavrov, IA, Zhao, KD, Grahn, PJ & Sayenko, DG 2021, , Journal of Clinical Medicine, vol. 10, no. 21, 4898. https://doi.org/10.3390/jcm10214898

Low-intensity and short-duration continuous cervical transcutaneous spinal cord stimulation intervention does not prime the corticospinal and spinal reflex pathways in able-bodied subjects
Sasaki, A, de Freitas, RM, Sayenko, DG, Masugi, Y, Nomura, T, Nakazawa, K & Milosevic, M 2021, , Journal of Clinical Medicine, vol. 10, no. 16, 3633. https://doi.org/10.3390/jcm10163633

Selectivity and excitability of upper-limb muscle activation during cervical transcutaneous spinal cord stimulation in humans
de Freitas, RM, Sasaki, A, Sayenko, DG, Masugi, Y, Nomura, T, Nakazawa, K & Milosevic, M 2021, , Journal of applied physiology, vol. 131, no. 2, pp. 746-759. https://doi.org/10.1152/japplphysiol.00132.2021

Transcutaneous spinal cord stimulation improves postural stability in individuals with multiple sclerosis
Roberts, BWR, Atkinson, DA, Manson, GA, Markley, R, Kaldis, T, Britz, GW, Horner, PJ, Vette, AH & Sayenko, DG 2021, , Multiple Sclerosis and Related Disorders, vol. 52, 103009. https://doi.org/10.1016/j.msard.2021.103009

Alterations of Spinal Epidural Stimulation-Enabled Stepping by Descending Intentional Motor Commands and Proprioceptive Inputs in Humans With Spinal Cord Injury
Gill, ML, Linde, MB, Hale, RF, Lopez, C, Fautsch, KJ, Calvert, JS, Veith, DD, Beck, LA, Garlanger, KL, Sayenko, DG, Lavrov, IA, Thoreson, AR, Grahn, PJ & Zhao, KD 2021, , Frontiers in Systems Neuroscience, vol. 14, 590231. https://doi.org/10.3389/fnsys.2020.590231

Potential impact of epidural stimulation on neurogenic bladder function and the value of urodynamic studies throughout usage
Beck, L, Veith, D, Linde, M, Gill, M, Calvert, J, Grahn, P, Garlanger, K, Husmann, D, Lavrov, I, Sayenko, D, Strommen, J, Lee, K & Zhao, K 2021, , Journal of Spinal Cord Medicine, vol. 44, no. 4, pp. 515-516. https://doi.org/10.1080/10790268.2021.1918979

A contemporary review of therapeutic and regenerative management of intracerebral hemorrhage
Sadaf, H, Desai, VR, Misra, V, Golanov, E, Hegde, ML, Villapol, S, Karmonik, C, Regnier-Golanov, A, Sayenko, D, Horner, PJ, Krencik, R, Weng, YL, Vahidy, FS & Britz, GW 2021, , Annals of Clinical and Translational Neurology, vol. 8, no. 11, pp. 2211-2221. https://doi.org/10.1002/acn3.51443, https://doi.org/10.1002/acn3.51443, https://doi.org/doi: 10.1002/acn3.51443

Epidural Electrical Stimulation of the Lumbosacral Spinal Cord Improves Trunk Stability During Seated Reaching in Two Humans With Severe Thoracic Spinal Cord Injury
Gill, ML, Linde, MB, Fautsch, K, Clinic, M, Lopez, C, Veith, DD, Calvert, JS, Beck, LA, Garlanger, K, Reggie Edgerton, V, Sayenko, D, Lavrov, IA, Thoreson, AR, Grahn, PJ & Zhao, KD 2020, , Frontiers in Systems Neuroscience, vol. 14, 79. https://doi.org/10.3389/fnsys.2020.569337

Complications of epidural spinal stimulation: lessons from the past and alternatives for the future
Taccola, G, Barber, S, Horner, PJ, Bazo, HAC & Sayenko, D 2020, , Spinal Cord, vol. 58, no. 10, pp. 1049-1059. https://doi.org/10.1038/s41393-020-0505-8

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