Diana Panesso

Diana Panesso, PhD

Associate Research Professor of Medicine, Academic Institute
Houston Methodist
Weill Cornell Medical College


Areas Of Expertise

Staphylococcus aureus Daptomycin resistance Enterococcus faecalis Daptomycin Enterococcus faecium Vancomycin
Education & Training

BSc, Pontificia Universidad Javeriana, Bogota
Training, Universidad El Bosque
Publications

Prevalence of the Cefazolin Inoculum Effect (CzIE) in Nasal Colonizing Methicillin-Susceptible Staphylococcus aureus in Patients from Intensive Care Units in Colombia and Use of a Modified Rapid Nitrocefin Test for Detection.
Carvajal, LP, Rincon, S, Gomez-Villegas, SI, Matiz-González, JM, Ordoñez, K, Santamaria, A, Ospina-Navarro, L, Beltran, J, Guevara, F, Mendez, YR, Salcedo, S, Porras, A, Valencia-Moreno, A, Grennia, H, Deyanov, A, Baptista, R, Tam, VH, Panesso, D, Tran, TT, Miller, WR, Arias, CA & Reyes, J 2024, , medRxiv. https://doi.org/10.1101/2024.07.11.24309236

LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium
Axell-House, DB, Simar, SR, Panesso, D, Rincon, S, Miller, WR, Khan, A, Pemberton, OA, Valdez, L, Nguyen, AH, Hood, KS, Rydell, K, DeTranaltes, AM, Jones, MN, Atterstrom, R, Reyes, J, Sahasrabhojane, PV, Suleyman, G, Zervos, M, Shelburne, S, Singh, KV, Shamoo, Y, Hanson, BM, Tran, TT & Arias, CA 2024, , Antimicrobial Agents and Chemotherapy, vol. 68, no. 3. https://doi.org/10.1128/aac.01069-23

Clinical Outcomes and Bacterial Characteristics of Carbapenem-resistant Acinetobacter baumannii Among Patients From Different Global Regions
Multi-Drug Resistant Organism Network Investigators 2024, , Clinical Infectious Diseases, vol. 78, no. 2, pp. 248-258. https://doi.org/10.1093/cid/ciad556

LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium
Axell-House, DB, Simar, SR, Panesso, D, Rincon, S, Miller, WR, Khan, A, Pemberton, OA, Valdez, L, Nguyen, AH, Hood, KS, Rydell, K, DeTranaltes, AM, Jones, MN, Atterstrom, R, Reyes, J, Sahasrabhojane, PV, Suleyman, G, Zervos, M, Shelburne, S, Singh, KV, Shamoo, Y, Hanson, BM, Tran, TT & Arias, CA 2024, , Antimicrobial Agents and Chemotherapy, vol. 68, no. 3. https://doi.org/10.1128/aac.01069-23

Clinical Outcomes and Bacterial Characteristics of Carbapenem-resistant Acinetobacter baumannii Among Patients From Different Global Regions
Multi-Drug Resistant Organism Network Investigators 2024, , Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 78, no. 2, pp. 248-258. https://doi.org/10.1093/cid/ciad556

Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida
Simar, SR, Tran, TT, Rydell, KB, Panesso, D, Contreras, GA, Munita, JM, Cifuentes, RO, Abbo, LM, Sahasrabhojane, P, Dinh, AQ, Axell-House, DB, Savidge, T, Shelburne, SA, Hanson, BM & Arias, CA 2023, , Antimicrobial Agents and Chemotherapy, vol. 67, no. 1. https://doi.org/10.1128/aac.01284-22

Evaluation of Cefazolin High Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus (MSSA) Using Gold standard MICs and Rapid Colorimetric Test (RCT)
Malikazad, H, Rizvi, S, Venugopalan, V, Santevechi, B, Panesso, D, Singh, KV, Gomez, S, Tran, C, Jacques-Palaz, KD, Miller, WR & Arias, CA 2023, , 6th Annual Texas Medical Center Antimicrobial Resistance and Stewardship Conference, January 18-20, 2023, Houston, United States, 1/18/23 - 1/20/23.

Optimization of a Nitrocefin-Based Rapid Test for the Detection of the Cefazolin Inoculum Effect (CzIE) in MSSA
Villegas, SG, Panesso, D, Singh, KV, Rincon, S, Carvajal, LP, Jacques-Palaz, KD, Rizvi, S, Reyes, MI, Abbott, A, Burnham, CAD, Bard, JD, Westblade, LF, Fritz, S, Zimmer, B, Dingle, TC, Butler-Wu, S, Miller, WR, Reyes, J & Arias, CA 2023, , IDWeek 2023 , Boston, United States, 10/11/23 - 10/15/23.

Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida
Simar, SR, Tran, TT, Rydell, KB, Panesso, D, Contreras, GA, Munita, JM, Cifuentes, RO, Abbo, LM, Sahasrabhojane, P, Dinh, AQ, Axell-House, DB, Savidge, T, Shelburne, SA, Hanson, BM & Arias, CA 2023, , Antimicrobial Agents and Chemotherapy, vol. 67, no. 1, pp. e0128422. https://doi.org/10.1128/aac.01284-22, https://doi.org/10.1128/aac.01284-22

LiaF is required for LiaX mediated protection against daptomycin and LL-37 in Enterococcus faecalis OG1RF
Panesso, D, Singh, KV, Villegas, SG, Khan, A, Supandy, A, Nguyen, AH, Rincon, S, Wood, K, Dinh, A, Research, H, Miller, WR, Shamoo, Y, Tran, C & Arias, CA 2022, . in LiaF is required for LiaX mediated protection against daptomycin and LL-37 in Enterococcus faecalis OG1RF. <https://www.eventscribe.net/2022/IDWeek/searchGlobal.asp>

Characteristics of community-acquired carbapenem-resistant Enterobacterales
Shrestha, R, Luterbach, CL, Dai, W, Komarow, L, Earley, M, Weston, G, Herc, E, Jacob, JT, Salata, R, Wong, D, Anderson, D, Rydell, K, Arias, CA, Chen, L, VanDuin, D, Panesso, D & Tran, C 2022, , Journal of Antimicrobial Chemotherapy, vol. 77, no. 10, 10, pp. 2763-2771. https://doi.org/10.1093/jac/dkac239, https://doi.org/10.1093/jac/dkac239

Microbiologic Characterization of Clinical Enterococcus faecium Strains
Tran, C, Panesso, D & Arias, CA 2022, , 2022 MAPTA Summer Science Symposium, Houston, United States, 8/4/22 - 8/5/22.

Accesory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal groups 258 and 307 in Houston, TX
Shropshire, WC, Dinh, AQ, Earley, M, Komarow, L, Panesso, D, Rydell, K, Gomez-Villegas, SI, Miao, H, Hill, C, Chen, L, Patel, R, Fries, BC, Abbo, L, Cober, E, Revolinski, S, Luterbach, CL, Chambers, H, Fowler, VG, Bonomo, RA, VanDuin, D, Shelburne, S, Kreiswirth, BN, Hanson, BM & Arias, CA 2022, , mBio, vol. 13, no. 2.

Accessory Genomes Drive Independent Spread of Carbapenem- Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX
Shropshire, WC, Dinh, AQ, Earley, M, Komarow, L, Panesso, D, Rydell, K, Gómez-Villegas, SI, Miao, H, Hill, C, Chen, L, Patel, R, Fries, BC, Abbo, L, Cober, E, Revolinski, S, Luterbach, CL, Chambers, H, Fowler, VG, Bonomo, RA, Shelburne, SA, Kreiswirth, BN, van Duin, D, Hanson, BM & Arias, CA 2022, , mBio, vol. 13, no. 2, pp. e0049722. https://doi.org/10.1128/mbio.00497-22

LiaX, a Member of the LiaFSR System, is Essential for Cell Envelope Adaptation System in Enterococcus faecium
Tran, C, Panesso, D, Zhao, A, Khan, A, Axell-House, DB, Shamoo, Y & Arias, CA 2022, , IDWeek 2022, 10/19/22 - 10/23/22.

Polymorphisms in Key Regulatory Regions of the bla operon Correlate with the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus (MSSA)
Gomez-Villegas, SI, Rios, R, Diaz, L, Dinh, A, Panesso, D, Rincon, S, Carvajal, LP, Reyes, MI, Murray, BE, Miller, WR, Singh, KV, Reyes, J & Arias, CA 2021, . https://doi.org/doi: 10.1093/ofid/ofab466.199

Heterologous expression of liaX from Enterococcus faecium in an E. faecalis host
Tran, C, Panesso, D, Shamoo, Y & Arias, CA 2021, , 4th Annual Texas Medical Center Antimicrobial Resistance and Stewardship Conference, Houston, United States, 1/26/21 - 1/28/21.

Genomic Epidemiology of Vancomycin-Resistant Enterococcus faecium (VREfm) in Latin America: Revisiting The Global VRE Population Structure
Rios, R, Reyes, J, Carvajal, LP, Rincon, S, Panesso, D, Echeverri, AM, Dinh, A, Kolokotronis, SO, Narechania, A, Tran, TT, Munita, JM, Murray, BE, Planet, PJ, Arias, CA & Diaz, L 2020, , Scientific Reports, vol. 10, no. 1, 5636. https://doi.org/10.1038/s41598-020-62371-7

Dynamics of blaKPC-2 Dissemination from Non-CG258 Klebsiella pneumoniae to Other Enterobacterales via IncN Plasmids in an Area of High Endemicity
Rada, AM, de la Cadena, E, Agudelo, C, Capataz, C, Orozco, N, Pallares, C, Dinh, AQ, Panesso, D, Ríos, R, Diaz, L, Correa, A, Hanson, BM, Villegas, MV, Arias, CA & Restrepo, E 2020, , Antimicrobial Agents and Chemotherapy, vol. 64, no. 12, e01743-20. https://doi.org/10.1128/AAC.01743-20

Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in Enterococcus faecalis
Khan, A, Davlieva, M, Panesso, D, Rincon, S, Miller, WR, Diaz, L, Reyes, J, Cruz, MR, Pemberton, O, Nguyen, AH, Siegel, SD, Planet, PJ, Narechania, A, Latorre, M, Rios, R, Singh, KV, Ton-That, H, Garsin, DA, Tran, TT, Shamoo, Y & Arias, CA 2019, , Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 52, pp. 26925-26932. https://doi.org/10.1073/pnas.1916037116