David M. Brown, MD

Associate Professor of Clinical Ophthalmology, Institute for Academic Medicine
Associate Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

After completing his postdoctoral training, Dr. Brown joined the faculty at the Baylor College of Medicine as a Clinical Instructor in the Department of Ophthalmology. He received his faculty appointment at the Weill Medical College in 2006.

Description of Research

Dr. Brown’s research centers on clinical investigations to evaluate treatments for diabetic retinopathy, neovascular age-related macular degeneration, central retinal vein occlusion, and retinal detachment. Dr. Brown was a key investigator on the Anti-VEGF Antibody for the Treatment of Predominantly Classic Choroidal Neovascularization in Age-related Macular Degeneration (ANCHOR) Study and the Minimally classic/occult trial of the anti-VEGF antibody ranibizumab in the treatment of neovascular AMD (MARINA) Study which both demonstrated a statistically significant benefit of Lucentis (ranibizumab) over Visudyne (verteporfin photodynamic therapy [PDT]) in predominantly classic choroidal neovascularization (CNV). Dr. Brown is also a member of the Diabetic Retinopathy Clinical Research Network.

Areas Of Expertise

Diabetic retinopathy Neovascular age-related macular degeneration Central retinal vein occlusion Retinal detachment
Education & Training

MD, Baylor College of Medicine
Internship, Baylor College of Medicine
Clinical Fellowship
Residency, University of Iowa Hospitals and Clinics
Publications

Suprachoroidal space alterations following delivery of triamcinolone acetonide: Post-hoc analysis of the phase 1/2 HULK study of patients with diabetic macular edema
Lampen, SIR, Khurana, RN, Noronha, G, Brown, DM & Wykoff, CC 2018, Ophthalmic Surgery Lasers and Imaging Retina, vol. 49, no. 9, pp. 692-697. https://doi.org/10.3928/23258160-20180831-07

Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial
TREX-AMD Study Group 2018, American Journal of Ophthalmology, vol. 192, pp. 84-90. https://doi.org/10.1016/j.ajo.2018.05.008

Retinopathy Regression with Treat and Extend Ranibizumab for Diabetic Macular Edema
Payne, JF, Clark, WL, Bruce, BB, Wykoff, CC, Brown, DM, Menke, BM, Iverson, SM, Allen, KF, Boyer, DS & Treat & Extend Protocol in Patients with Diabetic Macular Edema Study Group 2018, Ophthalmology. https://doi.org/10.1016/j.ophtha.2018.03.046

Long-term outcomes with as-needed aflibercept in diabetic macular oedema: 2-year outcomes of the ENDURANCE extension study
Wykoff, CC, Ou, WC, Khurana, RN, Brown, DM, Lloyd Clark, W & Boyer, DS 2018, British Journal of Ophthalmology, vol. 102, no. 5, pp. 631-636. https://doi.org/10.1136/bjophthalmol-2017-310941

Changes in retinal ischaemic index correlate with recalcitrant macular oedema in retinal vein occlusion: WAVE study
Kwon, S, Wykoff, CC, Brown, DM, van Hemert, J, Fan, W & Sadda, SR 2018, British Journal of Ophthalmology, vol. 102, no. 8, pp. 1066-1071. https://doi.org/10.1136/bjophthalmol-2017-311475

Neovascular age-related macular degeneration management in the third year: Final results from the TREX-AMD randomised trial
Wykoff, CC, Ou, WC, Croft, DE, Payne, JF, Brown, DM, Clark, WL, Abdelfattah, NS & Sadda, SVR 2018, British Journal of Ophthalmology, vol. 102, no. 4, pp. 460-464. https://doi.org/10.1136/bjophthalmol-2017-310822

Comparison of monthly vs treat-and-extend regimens for individuals with macular edema who respond well to anti-vascular endothelial growth factor medications: Secondary outcomes from the SCORE2 randomized clinical trial
SCORE2 Investigator Group 2018, JAMA Ophthalmology, vol. 136, no. 4, pp. 337-345. https://doi.org/10.1001/jamaophthalmol.2017.6843

Targeted Retinal Photocoagulation for Diabetic Macular Edema with Peripheral Retinal Nonperfusion. Three-Year Randomized DAVE Trial
Brown, DM, Ou, WC, Wong, TP, Kim, RY, Croft, DE & Wykoff, CC 2018, Ophthalmology. https://doi.org/10.1016/j.ophtha.2017.11.026

Effect of adding dexamethasone to continued ranibizumab treatment in patients with persistent diabetic macular edema: A DRCR network phase 2 randomized clinical trial
Diabetic Retinopathy Clinical Research Network 2018, JAMA Ophthalmology, vol. 136, no. 1, pp. 29-38. https://doi.org/10.1001/jamaophthalmol.2017.4914

Elevated Choroidal Thickness and Central Serous Chorioretinopathy in the Fellow Eyes of Patients with Circumscribed Choroidal Hemangioma
Kim, RS, Jain, RR, Brown, DM, Bretana, ME, Kegley, EN, Singer, MA, Aragon, AV & Schefler, AC 2018, Ocular Oncology and Pathology, vol. 4, no. 6. https://doi.org/10.1159/000486864

Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17
Yu, JJ, Agrón, E, Clemons, TE, Domalpally, A, van Asten, F, Keenan, TD, Cukras, C, Chew, EY, Chew, EY, Ferris, FL, SanGiovanni, JP, Agrón, E, Clemons, T, Lindblad, A, Lindblad, R, Shah, N, Sperduto, R, McBee, W, Gensler, G, Harrington, M, Henning, A, Jones, K, Thotapally, K, Tull, D, Watson, V, Williams, K, Gentry, C, Kaufman, F, Morrison, C, Saverino, E, Schenning, S, Blodi, B, Davis, M, Domalpally, A, Glander, K, Guilfoil, G, Hubbard, LD, Johnson, K, Nardi, B, Neider, M, Robinson, N, Rosensteel, E, Wabers, H, Zhang, G, Capone, A, Dass, B, Drenser, K, Garretson, BR, Hassan, TS, Trese, M, Williams, GA, Wolfe, J, Bell, T, Zajechowski, M, Bezaire, D, McIver, F, Medina, A, Pagett, J, Smith, SH, Swartz, L, Treuter, T, Antoszyk, A, Brown, J, Browning, DJ, Holland, W, Karow, A, Stalford, K, Price, A, Ennis, S, Fredenberg, S, Herby, J, Balasubramaniam, U, Clark, L, McClain, D, McOwen, M, Watson, L, Klein, M, Bailey, ST, Hwang, TJ, Lauer, A, Stout, JT, McCollum, P, Johnson, M, Rice, PB, Kim, I, Loewenstein, J, Miller, J, Sobrin, L, Young, L, Sullivan, J, Houlihan, P, Merry, L, Lane, AM, Bator, UL, Evans, C, Brett, S, Callahan, C, Grillo, M, Walsh, D, Zimmerman, KL, Anand, R, Coors, LE, Fuller, DG, Spencer, R, Wang, RC, Duignan, K, Arceneaux, S, Aguado, H, Hesse, N, Mackens, M, Swan, B, Wong, WT, Cukras, C, Dalal, M, Jacobs-El, N, Meyerle, C, Nicholson, B, Wiley, H, Shimel, KH, Garced, A, Oparah, J, Short, G, Temple, A, Ayukawa, B, Foster, G, Hayes, D, Koutsandreas, D, Nashwinter, R, Rowan, J, Bono, M, Cunningham, D, Palmer, M, Zetina, A, Orth, DH, Rezaei, K, Civantos, J, Hasan, S, Packo, K, Figliulo, C, Stanberry, P, Farmer, T, Nelson, K, Townsend-Patrick, S, Rosenfeld, P, Chen, R, Doshi, R, Dubovy, S, Kim, BT, Lowrance, M, Moshfeghi, A, Nahas, Z, Schienbaum, G, Vishak, J, Weng, C, Yehoshua, Z, Rodriguez, B, Rebimbas, J, Gleichauf, J, Kicak, M, Mena, J, Odem, T, Sferza-Camp, E, Disgdiertt, A, Oramas, J, Rams, I, Thatcher, S, Bressler, SB, Bressler, NM, Finkelstein, D, Sherman, SH, Solomon, S, Ying, HS, Denbow, R, Phillips, D, Radcliffe, E, Belt, J, Cain, D, Emmert, D, Herring, M, McDonald, J, Hubbard, GB, Bergstrom, CS, Cribbs, B, Hendrick, A, Johnson, B, Laird, P, Mehta, S, Olsen, T, Townsend, J, Yan, J, Yeh, S, Curtis, L, Brower, J, Yi, H, Dobbs, JR, Jordan, D, Elman, MJ, Liss, RA, Starr, JA, Belz, J, Putzulo, C, Coffey, T, Davis, A, Singletary, P, Andreani, GS, Cain, T, Ketner, D, Sotirakos, P, Chandra, S, Blodi, BA, Altaweel, MM, Danis, RP, Gottlieb, JL, Ip, M, Klein, R, Nork, TM, Stevens, TS, Burke, K, Olson, S, Dietzman, K, Soderling, B, Somers, G, Wealti, A, Krolnik, D, Peterson, J, Reed, S, Friberg, T, Eller, A, Gallagher, D, Labriola, L, Pokrifka, M, Gedansky, A, Anthony, N, Grzybowski, C, Matthews, D, Murajda-Jumba, S, Toro, J, Callanan, DG, Solley, WA, Williams, P, Lash, S, Boleman, B, Dock, C, Fish, GE, Shami, M, Arrington, B, Meeks, A, Margherio, AR, Raphaelian, P, Markus, D, Langdon, J, Truax, E, Lewis, S, Terry, B, Ruby, AJ, Noffke, A, Oh, K, Sarrafizadeh, R, Sneed, S, Hammersley, J, Neal, S, Doran, M, Jones, N, Preston, L, Jessick, H, Marsh, TT, Tolentino, M, Berger, A, Hamilton, R, Misch, D, Moon, SJ, Sutherland, D, Dilts, V, Henderson, S, Medina, E, Trueman, D, Holm, L, Strickland, J, Ie, D, Lipkowitz, JL, Shah, KB, Geraghty, S, Sannazzaro, B, Harper, M, Bayer, K, Lansing, MB, Fox, LB, Lee, R, Stallman, JB, Jacobson, M, Koh, S, Lampert, S, Miller, J, Rivellese, M, Sharma, A, Stoltz, RA, Vanderveldt, S, Marcus, L, Hendricks, S, Hollman, R, Betanzos, G, Ellorin, L, Fulbright, S, McCormick, D, Edwards, PA, Hall, J, Monk, M, Gutkowski, M, Mazurek, M, Murphy, J, Gusas, K, Moffett, C, Burley, D, Chesney, N, Kilgo, K, Rusinek, B, Stern, B, Troszak, T, Baker-Levingston, R, Baker, CW, Caldwell, T, Walker, T, Lambert, LF, Martin, T, Palmer, MJ, Williams, T, Novak, MA, Coney, J, Miller, DG, Pendergast, S, Singerman, L, Zakov, N, Zegarra, H, DuBois, K, Rath, S, Revella, L, Brink, T, Drury, K, Hogue, L, Ilc, M, Keller, C, McNamara, E, Tanner, V, Cunningham, T, DuBois, J, Greanoff, G, Nitzsche, T, Smith-Brewer, S, Isernhagen, RD, Kitchens, JW, Stone, TW, Wood, WJ, Holcomb, D, Therrien, V, Buck, M, Van Arsdall, J, Slade, E, Schneiderman, TE, Spinak, DJ, Gaedke, J, Brown, HD, Helgren, D, Pangelinan, JG, Halperin, L, Anagnoste, S, Dhalla, M, Rosenberg, K, Taney, B, Thompson, WS, Lopez, J, Hamlin, M, Lopez, M, Mariano, J, Quinchia, E, Aramayo, P, Veksler, R, Lee, M, Dreyer, R, Handelman, I, Ma, C, Peters, M, Hobbs, S, Milliron, A, Kopfer, M, Connaughton, M, Hoerner, AC, Logan, RJ, Wohlsein, HJ, Boyer, D, Chu, TG, Dayani, P, Liao, D, Novack, RL, Rahhal, FM, Roe, R, Tabandeh, H, Bayramyan, J, Gasparyan, T, Hoang, C, Kurokouchi, J, Lo, TE, Ngo, R, Nguyen, MA, Peyton, M, Yoon, C, Sierra, J, Zamboni, A, Kessinger, J, Protacio, E, Smucker, A, Rath, P, Bergren, R, Doft, B, Liu, J, Olsen, K, Merlotti, L, Ingram, W, Marfisi, K, Yeckel, K, Carmelo, HS, Fec, A, McBroom, K, Steinberg, D, Levy, M, Abrams, J, Chen, M, Torres, W, Jelemensky, P, Prybylski, M, Raphael, T, Appleby, D, Rodman, C, Sneath, M, Rosa, RH, Hoelscher, V, Castano, A, Parker, J, Hoskins, J, Anderson, N, Googe, J, McMillan, TA, Miller, J, Perkins, S, Oliver, K, Beerbower, J, Gilliland, B, Hunt, C, Jacobus, M, Lince, R, Morris, C, Oelrich, S, Whetstone, J, Chan, CK, Lin, S, Brown, DM, Gonzales, T, Myers, L, Fish, RH, Kim, RY, Major, JC, Wong, TP, Fish, RH, Kim, RY, Major, J, Wong, TP, Wycoff, C, Cone, C, Gilaspia, DG, Landaverde, N, Smith, R, Zamora, D, Sneed, V, Vela, M, Kegley, E, Greven, C, Kurup, S, Richards, C, Slusher, M, Everhart, C, Fish, J, Miller, D, Tyler, M, Jumper, JM, Fu, AD, Johnson, RN, Lujan, B, McDonald, HR, Rodriguez, R, Ansari, N, Joaquin, J, Linares, S, Lopez, L, Sabio, J, Grout, S, Indermill, C, Urias, Y, Zimmerman, R, Margulies, L, Schmidt, SJ, Meier, JL, Hadley, SL, Rosenthal, W, Johnson, B, Swafford, L, Shields, R, Varner, RS, Rosen, R, Gentile, R, Rivas, M, Tai, KW, Carrasquillo-Boyd, W, Masini, R, Stoller, G, Carnevale, K, LaRosa, DM, Burger, B, Conway, T, Del Castillo, C, Diaz, J, Jones, S, Mondoc, N, Balfour, C, Vitha, CH, Lutz, J, McGinley, B, El Baba, F, Lavorna, AM, Jones, R, Lewis, J, Tenzler, R, Salvas-Mladek, M, Van Kesteren, D, McLean, WC, Bridges, WZ, Stone, C, Ammons, D, Lamy, M, Menzel, A, Raymer, LD, Campbell, B, Hawkins, L, Rickman, L, Sherlin, L, Price, P, Sinyai, A, Kingsley, R, Bradford, RH, Leonard, RE, Icks, S, Bergman, V, Ross, B, Burris, R, Butt, A, Richmond, R, Lyon, A, Gill, M, Jampol, L, Mizra, R, Rozenbajgier, Z, Chapman, J, Kaminski, L, Degillio, A, Simjanoski, E, Heier, J, Cho, H, Cleary, TS, Goldman, D, Shah, C, Topping, T, Weber, M, Wiegand, T, Schindelheim, J, Bankert, J, Stone, J, Nowak, A, Chong, S, Williams, L, Bennett, S, Donovan, D, Graham, M, Jones, C, Fung, A, Bayabo, JK, Bosch, R, Cruz, E, Emerson, A, Fleming, A, Barsness, D, Rodriguez, J, Soboleva, M, Scott, IU, Bowie, E, Neely, KA, Quillen, DA, Walter, L, Bennett, T, Strong, J, Wells, J, Clark, L, Miller, P, Taylor, M, Swinford, T, Spivey, R, Banach, M, Ho, L, Lanning, R, Pheasant, TR, Prensky, JG, Truong, S, Teatsworth, J, Dietrich, M, Wasilus, A, Miller, A, Rakes, M, Slagle, T, Richards, M, Schuessler, P, Stover, L, Beer, P, Falk, NS, Shannon, MB, Olmeda, J, Berdeen, D, Fisher, JF, Folk, J, Russell, S, Taylor, B, Hinz, C, Walshire, J, Stockman, H, Critser, B, Karakas, S, Montague, C, Verdick, R, Gupta, O, Maguire, J, Brady, C, DeCroos, FC, Dollin, M, Garg, S, Gerstenblith, A, Haller, J, Ho, AC, Hsu, J, Kaiser, R, Pitcher, J, Regillo, C, Shah, R, Spirn, M, Tasman, W, Vander, J, Senderowitsch, N, Formoso, M, Markun, M, George, C, Centinaro, C, Grande, L, Carey, S, Liebenbaum, E, Sadda, SV, Humayun, M, Sierra, R, Corona, E, Padilla, M, Nu, M, Ramos, S, Barnett, C, Currie, G, Gottlieb, C, Garfinkel, R, Berinstein, D, Colyer, M, Deegan, W, Min-Shyue Lai, M, Murphy, R, Osman, M, Rivers, M, Sanders, R, von Fricken, MA, Oliver, D, Kirshon, J, Snowden, TA, Blondo, T, Cronise, A, Denny, V, Mendez, K, Newgen, J, Davis, J, Flory, M, Frantz, R, Murphy, B, Rauch, S, Kim, JE, Bachman, J, Connor, TB, Han, DP, Stepian, K, Weinberg, DV, Wirostko, WJ, Packard, K, Kaczanowski, T, Williams, V, Barwick, V, Flanders, J, Backes, D, Beringer, J, Keller, K, Selchert, K, Bernstein, P, Teske, M, Vitale, A, Allman, S, Carlstrom, B, Wegner, K, Haroldsen, A, Harrison, D, Fry, C, Gilman, J, Jenkins, G, Morris, P, Rauser, M, Fan, J, Suthar, M, Santiago, G, Halsey, KR, Quesada, C, Kiernan, W, Knabb, J, Lewis, RA, Dorenbach, C, Spencer, S, Barnett, D, Morales, J, Fishburne, BC, Gross, JG, Magee, MA, Flowers, A, McDowell, A, Price, R, Huang, S, Tang, J, Wilker, S, Hornsby, C, Ferguson, L, Krogstad, K, Adamovsky, R, Allchin, P, Carlton, K, Clow, C, Sholtis, K, Burke, S, Harrod, M, Hrvatin, S, Pankhurst, G, Sabates, NR, Cassell, M, Desai, K, Poulose, A, Sabates, F, Chen, Y, Gallimore, G, Konior, Y, Kim, N, Uwaydat, S, Troillett, D, Aletter, K, Frank, RN, Abrams, G, Puklin, J, Tewari, A, Milanovic, C, Bailey, M, Griffith, D, McDonald, D, Morehead, K, Sadikovic, Z, Schillace, L, Silvis, E, Joondeph, B, Christmas, N, Johnson, D, Kimura, A, Liu, M, Petty, S, Zilis, J, Benitez, J, Catlett, CB, Fluegel, E, Mowry, S, Nguyen, H, Reflow, D, Houghton, OM, Garg, S, Landers, MB, Meredith, T, Barnhart, S, Karmalkar, M, Cantrell, D, Esquejo-Leon, RL, Manor, L, Pope, S, Stines, D, Stokely, A, Hainsworth, D, Helming, D, Eichelberger, D, Leaton, MP, Hamm, C, Chaum, E, Iannaccone, A, Jennings, B, Murray, T, Mastellone, J, Millay, R, Kim, B, Goddard, T, Beaudette, LJ, Changelian-Aitken, N, Corrada, F, Dubuque, J, Iezzi, R, Bakri, SJ, Pulido, JS, Vogen, D, Nielsen, R, Berg, K, Burrington, J, Howard, S, Overend, J, Krason, Z, Lewison, D, Link, T, Blinder, KJ, Engelbrecht, NE, Grand, MG, Joseph, DP, Shah, GK, Smith, B, Thomas, M, Weeks, R, Boyd, L, Gabel, D, Adelman, R, Huang, J, Kempton, J, Parnes, A, Dupont, J, Perotti, E, Donaldson, V, Fong, K, Ossorio, P, Agarwal, A, Sternberg, P, Owings, S, Adkins, T, Lok, E, Munn, G, Skellie, B, Bhagat, N, Roy, MS, Zarbin, M, Fay, C, Lazar, M, Malpica, B, Mikheyav, T, Ulanski, L, Lim, J, Niec, M, Johnson, T, Ovando, Y, Carroll, CN, Janowicz, M, Schwartz, S, Cupp, D, Gorin, M, Heilweil, G, Hosseini, H, Hubschman, JP, Kreiger, A, McCannel, TY, Pan, C, Sarraf, D, Tsui, I, Udoetek, J, Voleti, V, Hitchcock, L, Ostrick, R, Chun, M, Kageyama, J, Davila, N, Lipka, K, Shin, C, Owsley, C, Albert, M, Feist, R, Mason, J, Thomley, M, Johnson, A, Clark, M, Emond, T, Hamela, J, Marsh, A, Searcey, K, Rookard, K, He, YG, Ufret-Vincenty, RL, Molai, M, Anderson, W, Horna, J, Letson, A, Cebulla, C, Chang, S, Davidorf, F, Salerno, J, Sladoje, L, Stetson, C, Perry, J, Savage, S, Toth, C, Jaffe, G, Schuman, S, Sarin, N, Crowell, J, Keaton, T, Kelly, M, Lutman, B, Skelly, M, Welch, L, Morse, L, Hunter, A, Soon-Chun Park, S, Wallace, C, Dhillon, E, Salvador, M, Holderreed, B, Chandra, K, Kaur, S, Redenbo, E, Hom, S, Cooney, M, Barbazetto, I, Klancnik, JM, Sorenson, JA, Yannuzzi, L, Scolaro, M, Agresta, E, Gonzalez, N, Grover, S, Chalam, KV, Gupta, S, Lyons, C, Li, W, Patel, C, Carrion, J, Ferreyra, H, Rodriguez, A, Molina, I, Balea, G, Emory, P, Rico, M, Siqueiros, G, Brucker, AJ, Dunaief, J, Grunwald, J, Kim, B, Maguire, AM, VanderBeek, B, Drossner, S, DuPont, J, Salvo, R, Berger, J, Devine, C, Nyberg, B, Weeney, L, DiLoreto, D, Chung, M, Davis, V, MacDowell, P, Gara, GO, Castillo, D, Czubinski, A, Keim, M, Hardy, B, Hollar, RG, Schueckler, L, Lyon, AT, Weinberg, A, Shiloach, M, Pelkofer, N, Zhou, Q, McPoland, L, Apte, R, Rao, PK, Pistorius, S, Kambarian, J, Adcock, E, Gould, S, Quinn, M, Curtis, R, Frost, A, Meyer, C & Rathert, G 2018, Ophthalmology. https://doi.org/10.1016/j.ophtha.2018.08.017

Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema
Jampol, LM, Glassman, AR, Liu, D, Aiello, LP, Bressler, NM, Duh, EJ, Quaggin, S, Wells, JA & Brown, DM 2018, Ophthalmology. https://doi.org/10.1016/j.ophtha.2018.01.019

Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema
Jampol, LM, Glassman, AR, Liu, D, Aiello, LP, Bressler, NM, Duh, EJ, Quaggin, S, Wells, JA & Brown, DM 2018, Ophthalmology. https://doi.org/10.1016/j.ophtha.2018.01.019

Intravitreal aflibercept for proliferative diabetic retinopathy
Brown, DM & Wykoff, CC 2017, The Lancet, vol. 390, no. 10108. https://doi.org/10.1016/S0140-6736(17)32445-5

Relationship Between Visual Acuity and Retinal Thickness During Anti–Vascular Endothelial Growth Factor Therapy for Retinal Diseases
Ou, WC, Brown, DM, Payne, JF & Wykoff, CC 2017, American Journal of Ophthalmology, vol. 180, pp. 8-17. https://doi.org/10.1016/j.ajo.2017.05.014

Randomized Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: 2-Year Results of the TREX-AMD Study
TREX-AMD Study Group 2017, Kidney International Reports, vol. 2, no. 4, pp. 314-321. https://doi.org/10.1016/j.oret.2016.12.004

Oral tyrosine kinase inhibitor for neovascular age-related macular degeneration: A phase 1 dose-escalation study
Jackson, TL, Boyer, D, Brown, DM, Chaudhry, N, Elman, M, Liang, C, OShaughnessy, D, Parsons, EC, Patel, S, Slakter, JS & Rosenfeld, PJ 2017, JAMA Ophthalmology, vol. 135, no. 7, pp. 761-767. https://doi.org/10.1001/jamaophthalmol.2017.1571

Reply
Wykoff, CC, Le, RT, Khurana, RN, Brown, DM, Ou, WC, Wang, R, Clark, WL & Boyer, DS 2017, American Journal of Ophthalmology, vol. 177, pp. 236-237. https://doi.org/10.1016/j.ajo.2017.02.024

The potential importance of detection of neovascular age-related macular degeneration when visual acuity is relatively good
Ho, AC, Albini, TA, Brown, DM, Boyer, DS, Regillo, CD & Heier, JS 2017, JAMA Ophthalmology, vol. 135, no. 3, pp. 268-273. https://doi.org/10.1001/jamaophthalmol.2016.5314

Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial
Abdelfattah, NS, Al-Sheikh, M, Pitetta, S, Mousa, A, Sadda, SVR, Wykoff, CC, Wykoff, CC, Croft, DE, Brown, DM, Wang, R, Payne, JF, Clark, L, Abdelfattah, NS, Sadda, SVR, Chen, E, Fish, RH, Fish, RH, Kim, RY, Major, JC, Major, JC, Schefler, AC, Shah, AR, Shah, AR, Vance, SK, Wong, TP & Wong, TP 2017, Ophthalmology, vol. 124, no. 2, pp. 215-223. https://doi.org/10.1016/j.ophtha.2016.10.002

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