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Dan Peer, PhD

Full Affiliate Member, Research Institute
Houston Methodist


Publications

Progress and challenges towards targeted delivery of cancer therapeutics
Rosenblum, D, Joshi, N, Tao, W, Karp, JM & Peer, D 2018, Nature Communications, vol 9, no. 1, 1410. DOI: 10.1038/s41467-018-03705-y

A modular platform for targeted RNAi therapeutics
Kedmi, R, Veiga, N, Ramishetti, S, Goldsmith, M, Rosenblum, D, Dammes, N, Hazan-Halevy, I, Nahary, L, Leviatan-Ben-Arye, S, Harlev, M, Behlke, M, Benhar, I, Lieberman, J & Peer, D 2018, Nature Nanotechnology, pp. 1-6. DOI: 10.1038/s41565-017-0043-5

Focus on RNA interference: From nanoformulations to in vivo delivery
Karp, JM & Peer, D 2018, Nanotechnology, vol 29, no. 1, 010201. DOI: 10.1088/1361-6528/aa98e3

Hierarchical theranostic nanomedicine: MRI contrast agents as a physical vehicle anchor for high drug loading and triggered on-demand delivery
Liu, G, Deng, J, Liu, F, Wang, Z, Peer, D & Zhao, Y 2018, Journal of Materials Chemistry B, vol 6, no. 13, pp. 1995-2003. DOI: 10.1039/c8tb00135a

Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics-An innate immune system standpoint
Granot, Y & Peer, D 2017, Seminars in Immunology. DOI: 10.1016/j.smim.2017.08.015

Next-Generation Lipids in RNA Interference Therapeutics
Rietwyk, S & Peer, D 2017, ACS Nano, vol 11, no. 8, pp. 7572-7586. DOI: 10.1021/acsnano.7b04734

Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation
Alvarez, MM, Aizenberg, J, Analoui, M, Andrews, AM, Bisker, G, Boyden, ES, Kamm, RD, Karp, JM, Mooney, DJ, Oklu, R, Peer, D, Stolzoff, M, Strano, MS, Trujillo-De Santiago, G, Webster, TJ, Weiss, PS & Khademhosseini, A 2017, ACS Nano, vol 11, no. 6, pp. 5195-5214. DOI: 10.1021/acsnano.7b01493

Comprehensive and Systematic Analysis of the Immunocompatibility of Polyelectrolyte Capsules
Zyuzin, MV, Díez, P, Goldsmith, M, Carregal-Romero, S, Teodosio, C, Rejman, J, Feliu, N, Escudero, A, Almendral, MJ, Linne, U, Peer, D, Fuentes, M & Parak, WJ 2017, Bioconjugate Chemistry, vol 28, no. 2, pp. 556-564. DOI: 10.1021/acs.bioconjchem.6b00657

Advanced strategies in immune modulation of cancer using lipid-based nanoparticles
Mizrahy, S, Hazan-Halevy, I, Landesman-Milo, D, Ng, BD & Peer, D 2017, Frontiers in Immunology, vol 8, no. FEB, 69. DOI: 10.3389/fimmu.2017.00069

Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond
Mitragotri, S, Lammers, T, Bae, YH, Schwendeman, S, De Smedt, S, Leroux, JC, Peer, D, Kwon, IC, Harashima, H, Kikuchi, A, Oh, YK, Torchilin, V, Hennink, W, Hanes, J & Park, K 2017, Journal of Controlled Release, vol 246, pp. 183-184. DOI: 10.1016/j.jconrel.2017.01.011

Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions
Anchordoquy, TJ, Barenholz, Y, Boraschi, D, Chorny, M, Decuzzi, P, Dobrovolskaia, MA, Farhangrazi, ZS, Farrell, D, Gabizon, A, Ghandehari, H, Godin, B, La-Beck, NM, Ljubimova, J, Moghimi, SM, Pagliaro, L, Park, JH, Peer, D, Ruoslahti, E, Serkova, NJ & Simberg, D 2017, ACS Nano, vol 11, no. 1, pp. 12-18. DOI: 10.1021/acsnano.6b08244

ECM-based macroporous sponges release essential factors to support the growth of hematopoietic cells
Soffer-Tsur, N, Peer, D & Dvir, T 2016, Journal of Controlled Release. DOI: 10.1016/j.jconrel.2016.09.021

Orchestrating a Symphony on a Single Conjugate: Aptamer Targeting, Gene Silencing, and Immunomodulation to Enhance Antitumor Response
Ng, BD & Peer, D 2017, Molecular Therapy, vol 25, no. 1, pp. 5-7. DOI: 10.1016/j.ymthe.2016.12.003

Current Progress in Non-viral RNAi-Based Delivery Strategies to Lymphocytes
Mizrahy, S, Hazan-Halevy, I, Dammes, N, Landesman-Milo, D & Peer, D 2017, Molecular Therapy. DOI: 10.1016/j.ymthe.2017.03.001

Immunomodulation of hematological malignancies using oligonucleotides based-nanomedicines
Hazan-Halevy, I, Landesman-Milo, D, Rosenblum, D, Mizrahy, S, Ng, BD & Peer, D 2016, Journal of Controlled Release. DOI: 10.1016/j.jconrel.2016.07.052

Harnessing nanomedicine for therapeutic intervention in glioblastoma
Gutkin, A, Cohen, ZR & Peer, D 2016, Expert Opinion on Drug Delivery, vol 13, no. 11, pp. 1573-1582. DOI: 10.1080/17425247.2016.1200557

Zooming in on selectins in cancer
Kedmi, R & Peer, D 2016, Science Translational Medicine, vol 8, no. 345, 345fs11. DOI: 10.1126/scitranslmed.aag1802

RNA nanomedicines: The next generation drugs?
Singh, MS & Peer, D 2016, Current Opinion in Biotechnology, vol 39, pp. 28-34. DOI: 10.1016/j.copbio.2015.12.011

Advances in RNAi therapeutic delivery to leukocytes using lipid nanoparticles
Ramishetti, S, Landesman-Milo, D & Peer, D 2016, Journal of Drug Targeting, pp. 1-7. DOI: 10.3109/1061186X.2016.1172587

Transforming Nanomedicines from Lab Scale Production to Novel Clinical Modality
Landesman-Milo, D & Peer, D 2016, Bioconjugate Chemistry, vol 27, no. 4, pp. 855-862. DOI: 10.1021/acs.bioconjchem.5b00607