Christof Karmonik

Christof Karmonik, PhD

Associate Research Professor of Translational Imaging, Academic Institute
Associate Research Member & Director, MRI Core, Research Institute
Houston Methodist
Weill Cornell Medical College

Research Lab

After completing his postdoctoral training in 2000, Dr. Karmonik joined the faculty at the Baylor College of Medicine in Houston, Texas as Instructor in the Department of Medicine. He became an Assistant Professor in the Department of Radiology there in 2002. In addition to his academic appointments, Dr. Karmonik was also a senior software engineer for the Schlumberger Companies. He joined Houston Methodist Hospital and Research Institute in 2005.

Description of Research

Dr. Karmonik’s research focuses on enhancing information in medical images by optimized acquisition techniques and advanced post-processing algorithms. Applications include visualization and quantification of hemodynamics in cerebral aneurysms to optimize outcome after flow diverter treatment using 4D phase contrast MRI and computational fluid dynamics together with 3D printing technology, understanding flow changes in the ascending aorta in patients with left ventricular flow devices and probing functional connectivity in the brain in health and disease. 

Areas Of Expertise

functional Magnetic Resonance Computational Fluid Dynamics Computational Surgery Brain imaging Image Processing
Education & Training

Postdoctoral Fellowship, University of Texas MD Anderson Cancer Center
Visiting Research Fellowship, National Institute of Standards and Technology
MS, University of the Saarland
PhD, University of the Saarland

Therapeutic effects of non-invasive, individualized, transcranial neuromodulation treatment for voiding dysfunction in multiple sclerosis patients: study protocol for a pilot clinical trial
Tran, K, Shi, Z, Karmonik, C, John, B, Rajab, H, Helekar, SA, Boone, T & Khavari, R 2021, , Pilot and Feasibility Studies, vol. 7, no. 1, 83.

Design, development, and temporal evaluation of a magnetic resonance imaging-compatible in vitro circulation model using a compliant abdominal aortic aneurysm phantom
Thirugnanasambandam, M, Canchi, T, Piskin, S, Karmonik, C, Kung, E, Menon, PG, Avril, S & Finol, EA 2021, , Journal of Biomechanical Engineering, vol. 143, no. 5, 051004.

High spatial correlation in brain connectivity between micturition and resting states within bladder-related networks using 7 T MRI in multiple sclerosis women with voiding dysfunction
Shi, Z, Tran, K, Karmonik, C, Boone, T & Khavari, R 2021, , World Journal of Urology.

A Dual-VENC Four-Dimensional Flow MRI Framework for Analysis of Subject-Specific Heterogeneous Nonlinear Vessel Deformation
Concannon, J, Hynes, N, McMullen, M, Smyth, E, Moerman, K, McHugh, PE, Sultan, S, Karmonik, C & McGarry, JP 2020, , Journal of Heat Transfer, vol. 142, no. 11, 114502.

Wall Enhancement, Hemodynamics, and Morphology in Unruptured Intracranial Aneurysms with High Rupture Risk
Lv, N, Karmonik, C, Chen, S, Wang, X, Fang, Y, Huang, Q & Liu, J 2020, , Translational Stroke Research, vol. 11, no. 5, pp. 882-889.

Protocol for a multicenter randomized, double blind, controlled pilot trial of higher neural function in overactive bladder patients after anticholinergic, beta-3 adrenergic agonist, or placebo
High, RA, Danford, JM, Shi, Z, Karmonik, C, Kuehl, TJ, Bird, ET & Khavari, R 2020, , Contemporary Clinical Trials Communications, vol. 19, 100621.

A pilot study using a machine-learning approach of morphological and hemodynamic parameters for predicting aneurysms enhancement
Lv, N, Karmonik, C, Shi, Z, Chen, S, Wang, X, Liu, J & Huang, Q 2020, , International Journal of Computer Assisted Radiology and Surgery, vol. 15, no. 8, pp. 1313-1321.

Growth Hormone Alters Brain Morphometry, Connectivity, and Behavior in Subjects with Fatigue after Mild Traumatic Brain Injury
Wright, T, Urban, R, Durham, W, Dillon, EL, Randolph, KM, Danesi, C, Gilkison, C, Karmonik, C, Zgaljardic, DJ, Masel, B, Bishop, J, Pyles, R, Seidler, R, Hierholzer, AH & Sheffield-Moore, M 2020, , Journal of Neurotrauma, vol. 37, no. 8, pp. 1052-1066.

Are White Matter Tract Integrities Different in Multiple Sclerosis Women With Voiding Dysfunction?
Tran, K, Karmonik, C, Boone, TB & Khavari, R 2020, , Female pelvic medicine & reconstructive surgery.

Higher neural contribution underlying persistent lower urinary tract symptoms in men with Benign Prostatic Hyperplasia undergoing bladder outlet procedures
Khavari, R, Hernandez, N, Karmonik, C, Shi, Z, Miles, BJ & Gonzalez, RR 2020, , Contemporary Clinical Trials Communications, vol. 17, 100498.

Brain activation patterns of female multiple sclerosis patients with voiding dysfunction
Khavari, R, Chen, J, Boone, TB & Karmonik, C 2020, , Neurourology and Urodynamics, vol. 39, no. 3, pp. 969-977.

Multimodal 18F-AV-1451 and MRI findings in nonfluent variant of primary progressive aphasia: Possible insights on nodal propagation of tau protein across the syntactic network
Pascual, B, Funk, Q, Zanotti-Fregonara, P, Pal, N, Rockers, E, Yu, MM, Spann, B, Román, GC, Schulz, PE, Karmonik, C, Appel, SH & Masdeu, JC 2020, , Journal of Nuclear Medicine, vol. 61, no. 2, pp. 263-269.

Similarity of individual functional brain connectivity patterns formed by music listening quantified with a data-driven approach
Karmonik, C, Brandt, A, Elias, S, Townsend, J, Silverman, E, Shi, Z & Frazier, JT 2019, , International Journal of Computer Assisted Radiology and Surgery, vol. 15, no. 4, pp. 703-713.

Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment
Berg, P, Voß, S, Janiga, G, Saalfeld, S, Bergersen, AW, Valen-Sendstad, K, Bruening, J, Goubergrits, L, Spuler, A, Chiu, TL, Tsang, ACO, Copelli, G, Csippa, B, Paál, G, Závodszky, G, Detmer, FJ, Chung, BJ, Cebral, JR, Fujimura, S, Takao, H, Karmonik, C, Elias, S, Cancelliere, NM, Najafi, M, Steinman, DA, Pereira, VM, Piskin, S, Finol, EA, Pravdivtseva, M, Velvaluri, P, Rajabzadeh-Oghaz, H, Paliwal, N, Meng, H, Seshadhri, S, Venguru, S, Shojima, M, Sindeev, S, Frolov, S, Qian, Y, Wu, YA, Carlson, KD, Kallmes, DF, Dragomir-Daescu, D & Beuing, O 2019, , International Journal of Computer Assisted Radiology and Surgery, vol. 14, no. 10, pp. 1795-1804.

In Reply: Relationship between Aneurysm Wall Enhancement in Vessel Wall Magnetic Resonance Imaging and Rupture Risk of Unruptured Intracranial Aneurysms
Lv, N, Karmonik, C, Huang, Q & Liu, J 2019, , Clinical Neurosurgery, vol. 84, no. 3, pp. E234.

Characterization of functional brain connectivity towards optimization of music selection for therapy: a fMRI study
Wu, K, Anderson, J, Townsend, J, Frazier, T, Brandt, A & Karmonik, C 2019, , International Journal of Neuroscience, pp. 1-9.

Data-driven machine-learning quantifies differences in the voiding initiation network in neurogenic voiding dysfunction in women with multiple sclerosis
Karmonik, C, Boone, T & Khavari, R 2019, , International Neurourology Journal, vol. 23, no. 3, pp. 195-204.

An Exploratory Pilot Study of Brain Activation and Functional Connectivity Induced by the “Goldberg” Variations 276 years after their Commission
Karmonik, C, Hirata, M, Elias, S & Frazier, JT 2019, , Medical Problems of Performing Artists, vol. 34, no. 4, pp. 191-197A.

Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: Segmentation
Berg, P, Voß, S, Saalfeld, S, Janiga, G, Bergersen, AW, Valen-Sendstad, K, Bruening, J, Goubergrits, L, Spuler, A, Cancelliere, NM, Steinman, DA, Pereira, VM, Chiu, TL, Tsang, ACO, Chung, BJ, Cebral, JR, Cito, S, Pallarès, J, Copelli, G, Csippa, B, Paál, G, Fujimura, S, Takao, H, Hodis, S, Hille, G, Karmonik, C, Elias, S, Kellermann, K, Khan, MO, Marsden, AL, Morales, HG, Piskin, S, Finol, EA, Pravdivtseva, M, Rajabzadeh-Oghaz, H, Paliwal, N, Meng, H, Seshadhri, S, Howard, M, Shojima, M, Sugiyama, SI, Niizuma, K, Sindeev, S, Frolov, S, Wagner, T, Brawanski, A, Qian, Y, Wu, YA, Carlson, KD, Dragomir-Daescu, D & Beuing, O 2018, , Cardiovascular Engineering and Technology, vol. 9, no. 4, pp. 565-581.

Similarity of functional connectivity patterns in patients with multiple sclerosis who void spontaneously versus patients with voiding dysfunction
Khavari, R, Elias, SN, Boone, T & Karmonik, C 2018, Neurourology and Urodynamics. DOI: 10.1002/nau.23837