Edward Brian Butler, MD

Jim and Joan Harrell Chair in Radiation Oncology, Department of Radiation Oncology
Professor of Radiation Oncology, Academic Institute
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Butler graduated from Georgetown University School of Medicine in Washington, D.C. in 1982.  He started his residency at Wilford Hall USAF Medical Center in San Antonio, Texas in 1982 and then completed his residency as Chief Resident at Stanford University Medical Center in 1986.  After completing his postdoctoral training in 1987, Dr. Butler returned to the Wilford Hall USAF Medical Center where he became both the Chief of Radiation Oncology and the Chief of Brachytherapy. He also joined the faculty at The University of Texas Health Science Center at San Antonio as a Clinical Assistant Professor that same year. Dr. Butler would later join the Baylor College of Medicine where he would eventually become a full professor and the Chief of Radiation Oncology for both the medical school and the VA Hospital. He became the Medical Director of Radiation Oncology at Methodist in 1991, and received his faculty appointment at the Weill Medical School in 2006.  He became Chair of Radiation Oncology at Houston Methodist in 2008.  In 2016, Dr. Butler was named the Jim and Joan Harrell Chair in Radiation Oncology.

Description of Research

Dr. Butler’s research centers on preclinical and clinical studies that combine radiation therapy and gene therapy for the treatment of prostate cancer. In recent years, he has extended these successful studies to other cancers, notably pancreatic cancer. His research interests also include three-dimensional reconstruction of body organs to assist in better localization of radiation therapy.

Areas Of Expertise

Radiation therapy Prostate cancer Gene therapy Pancreatic cancer Computer visualization techniques
Education & Training

Residency, Stanford School of Medicine
MD, Georgetown University
Patents

IMPLANTABLE NANOCHANNEL DELIVERY DEVICES

Patent Number: US2018125780, May 10 2018


IMPLANTABLE NANOCHANNEL DELIVERY DEVICES

Patent Number: WO2016187100, Nov 24 2016

Publications

Approach to radiation therapy in the Jehovah's Witness patient: An overview
Jurica, JM, Messer, JA, Teh, BS, Butler, EB & Farach, AM 2020, , Reports of Practical Oncology and Radiotherapy, vol. 25, no. 6, pp. 856-859. https://doi.org/10.1016/j.rpor.2020.08.014

Prognostic role of chemotherapy, radiotherapy dose, and extent of surgical resection in adult medulloblastoma
Haque, W, Verma, V, Brian Butler, E & Teh, BS 2020, , Journal of Clinical Neuroscience, vol. 76, pp. 154-160. https://doi.org/10.1016/j.jocn.2020.04.002

Clinical presentation, national practice patterns, and outcomes of breast adenomyoepithelioma
Haque, WM, Verma, V, Suzanne Klimberg, V, Nangia, J, Schwartz, M, Butler, EB & Teh, BS 2020, Breast Journal, vol. 26, no. 4, pp. 653-660. https://doi.org/10.1111/tbj.13638

Patterns of management and outcomes of unifocal versus multifocal glioblastoma
Haque, W, Thong, Y, Verma, V, Rostomily, R, Butler, EB & Teh, BS 2020, , Journal of Clinical Neuroscience, vol. 74, pp. 155-159. https://doi.org/10.1016/j.jocn.2020.01.086

Post-treatment mortality after definitive chemoradiotherapy versus resection for esophageal cancer
Jiang, W, Verma, V, Haque, W, Moreno, AC, Koshy, M, Butler, EB & Teh, BS 2020, Diseases of the Esophagus, vol. 33, no. 4. https://doi.org/10.1093/dote/doz073

Comparison of outcomes between metaplastic and triple-negative breast cancer patients
Polamraju, P, Haque, W, Cao, K, Verma, V, Schwartz, M, Klimberg, VS, Hatch, S, Niravath, P, Butler, EB & Teh, BS 2020, , Breast, vol. 49, pp. 8-16. https://doi.org/10.1016/j.breast.2019.10.003

Controversies in the Management of Solid Tumor Bone Metastases
Farach, AM, Butler, EB & Teh, BS 2020, . in Medical Radiology. Medical Radiology, Springer, pp. 241-253. https://doi.org/10.1007/174_2019_217

Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1
Liu, HC, Viswanath, DI, Pesaresi, F, Xu, Y, Zhang, L, Di Trani, N, Paez-Mayorga, J, Hernandez, N, Wang, Y, Erm, DR, Ho, J, Susnjar, A, Liu, X, Demaria, S, Chen, SH, Teh, BS, Butler, EB, Xuan Chua, CY & Grattoni, A 2020, , International Journal of Radiation Oncology Biology Physics. https://doi.org/10.1016/j.ijrobp.2020.07.2326

Eye plaque brachytherapy versus enucleation for ocular melanoma: an analysis from the National Cancer Database
Messer, JA, Zuhour, RJ, Haque, W, Lewis, GD, Schefler, AC, Wong, A, Bernicker, EH, Chevez-Barrios, P, Michelle Quan, E, Farach, A, Butler, EB, Hatch, SS & Teh, BS 2020, , Journal of Contemporary Brachytherapy, vol. 12, no. 4, pp. 303-310. https://doi.org/10.5114/jcb.2020.98108

Neoadjuvant radiation therapy for esophageal cancer: Is a higher dose better?
Haque, W, Butler, EB & Teh, BS 2019, Journal of Thoracic Disease, vol. 11, no. 12, pp. 5631-5634. https://doi.org/10.21037/jtd.2019.11.77

Toxicity of pelvic nodal radiation for localized prostate cancer
Haque, W, Butler, EB & Teh, BS 2019, Annals of translational medicine, vol. 7, no. Suppl 8, pp. S359. https://doi.org/10.21037/atm.2019.09.57

Co-registration of MR and FDG-PET imaging for stereotactic radiotherapy planning; case report in a previously irradiated brain metastasis with recurrent tumor and radiation necrosis
Scranton, RA, Sadrameli, S, Butler, EB, Farach, A, Wang, H-C, Teh, BS, Tremont-Lukats, IW, Fung, SH, Zanotti-Fregonara, P & Rostomily, RC 2019, , Practical Radiation Oncology. https://doi.org/10.1016/j.prro.2019.11.008

Omission of radiation therapy following breast conservation in older (=70 years) women with T1-2N0 triple-negative breast cancer
Haque, WM, Verma, V, Hsiao, KY, Hatch, S, Arentz, C, Szeja, S, Schwartz, M, Niravath, PA, Bonefas, E, Miltenburg, D, Butler, EB & Teh, BS 2019, Breast Journal, vol. 25, no. 6, pp. 1126-1133. https://doi.org/10.1111/tbj.13443

The impact of molecular status on survival outcomes for invasive micropapillary carcinoma of the breast
Lewis, GD, Xing, Y, Haque, WM, Patel, T, Schwartz, MR, Chen, AC, Farach, AM, Hatch, SS, Butler, EB, Chang, JC & Teh, BS 2019, Breast Journal, vol. 25, no. 6, pp. 1171-1176. https://doi.org/10.1111/tbj.13432

A matter of comprehensive informed consent: Short-term mortality rates with definitive treatment options in elderly stage i NSCLC
Dalwadi, SM, Savjani, RR, Bernicker, EH, Butler, EB, Teh, BS & Farach, AM 2019, American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 42, no. 11, pp. 851-855. https://doi.org/10.1097/COC.0000000000000606

Biopsy proven metastatic meningioma: A case report and review of the literature
Vakil, H, Tran, L, Lewis, GD, Cykowski, MD, Butler, EB & Teh, BS 2019, Reports of Practical Oncology and Radiotherapy, vol. 24, no. 6, pp. 528-532. https://doi.org/10.1016/j.rpor.2019.08.002

Socioeconomic Factors Associated with Lack of Treatment in Early Stage Non-Small Cell Lung Cancer
Dalwadi, SM, Zhang, J, Bernicker, EH, Butler, EB, Teh, BS & Farach, AM 2019, Cancer Investigation, vol. 37, no. 9, pp. 506-511. https://doi.org/10.1080/07357907.2019.1666136

Prognosis of lymphotropic invasive micropapillary breast carcinoma analyzed by using data from the National Cancer Database
Lewis, GD, Xing, Y, Haque, WM, Patel, T, Schwartz, M, Chen, A, Farach, AM, Hatch, SS, Butler, EB, Chang, JC & Teh, BS 2019, , Cancer Communications, vol. 39, no. 1, 60. https://doi.org/10.1186/s40880-019-0406-4

Short-term Mortality Associated with Definitive Chemoradiotherapy Versus Radical Cystectomy for Muscle-invasive Bladder Cancer
Haque, W, Verma, V, Aghazadeh, M, Darcourt, J, Butler, EB & Teh, BS 2019, , Clinical Genitourinary Cancer, vol. 17, no. 5, pp. e1069-e1079. https://doi.org/10.1016/j.clgc.2019.06.015

Neoadjuvant stereotactic body radiation therapy for nonmetastatic pancreatic adenocarcinoma
Jiang, W, Haque, W, Verma, V, Butler, EB & Teh, BS 2019, , Acta Oncologica, vol. 58, no. 9, pp. 1259-1266. https://doi.org/10.1080/0284186X.2019.1631472