E. Brian Butler, MD

Jim and Joan Harrell Chair in Radiation Oncology, Department of Radiation Oncology
Professor of Radiation Oncology, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

After completing his postdoctoral training in 1987, Dr. Butler returned to the Wilford Hall USAF Medical Center in San Antonio, Texas where he became both the Chief of Radiation Oncology and the Chief of Brachytherapy. He also joined the faculty at The University of Texas Health Science Center at San Antonio as a Clinical Assistant Professor that same year. Dr. Butler would later join the Baylor College of Medicine where he would eventually become a full professor and the Chief of Radiation Oncology for both the medical school and the VA Hospital. He became the Medical Director of Radiation Oncology at Methodist in 1991, and received his faculty appointment at the Weill Medical School in 2006.

Description of Research

Dr. Butler’s research centers on preclinical and clinical studies that combine radiation therapy and gene therapy for the treatment of prostate cancer. In recent years, he has extended these successful studies to other cancers, notably pancreatic cancer. His research interests also include three-dimensional reconstruction of body organs to assist in better localization of radiation therapy.

Areas Of Expertise

Radiation therapy Prostate cancer Gene therapy Pancreatic cancer Computer visualization techniques
Education & Training

Residency, Stanford School of Medicine
MD, Georgetown University
Publications

Utilization of intensity modulated radiation therapy for anal cancer in the United States
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Journal of Gastrointestinal Oncology, vol 9, no. 3, pp. 466-477. DOI: 10.21037/jgo.2018.03.03

Utilization of hysterectomy following chemoradiation for IB2/IIA2 cervical cancer in the national cancer data base
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Anticancer Research, vol 38, no. 5, pp. 3175-3179. DOI: 10.21873/anticanres.12581

Response rates and pathologic complete response by breast cancer molecular subtype following neoadjuvant chemotherapy
Haque, W, Verma, V, Hatch, S, Suzanne Klimberg, V, Brian Butler, E & Teh, BS 2018, Breast Cancer Research and Treatment, pp. 1-9. DOI: 10.1007/s10549-018-4801-3

Omission of radiotherapy in elderly women with early stage metaplastic breast cancer
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Breast, vol 38, pp. 154-159. DOI: 10.1016/j.breast.2018.01.005

Utilization of radiotherapy and stereotactic body radiation therapy for renal cell cancer in the USA
Haque, W, Verma, V, Lewis, GD, Lo, SS, Butler, EB & Teh, BS 2018, Future Oncology, vol 14, no. 9, pp. 819-827. DOI: 10.2217/fon-2017-0536

Utilization of neoadjuvant intensity-modulated radiation therapy and proton beam therapy for esophageal cancer in the United States
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Journal of Gastrointestinal Oncology, vol 9, no. 2, pp. 282-294. DOI: 10.21037/jgo.2017.11.14

The impact of comorbidity on overall survival in elderly nasopharyngeal carcinoma patients: A National Cancer Data Base analysis
Huang, Y, Chen, W, Haque, W, Verma, V, Xing, Y, Teh, BS & Brian Butler, E 2018, Cancer Medicine. DOI: 10.1002/cam4.1377

Radiation Oncology in the Face of Natural Disaster: The Experience of Houston Methodist Hospital
Mireles, M, Pino, R, Teh, BS, Farach, A, Joseph, A & Butler, EB 2018, International Journal of Radiation Oncology Biology Physics, vol 100, no. 4, pp. 813-815. DOI: 10.1016/j.ijrobp.2017.12.002

Clinical benefit to regionalization of care for muscle invasive bladder cancer
Haque, W, Butler, EB & Teh, BS 2018, Translational Andrology and Urology, vol 7, pp. S98-S100. DOI: 10.21037/tau.2018.01.05

Radiation dose in neoadjuvant chemoradiation therapy for esophageal cancer: Patterns of care and outcomes from the National Cancer Data Base
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Journal of Gastrointestinal Oncology, vol 9, no. 1, pp. 80-89. DOI: 10.21037/jgo.2017.09.12

Trends in Cardiac Mortality in Patients With Locally Advanced Non-Small Cell Lung Cancer
Haque, W, Verma, V, Fakhreddine, M, Butler, EB, Teh, BS & Simone, CB 2018, International Journal of Radiation Oncology Biology Physics, vol 100, no. 2, pp. 470-477. DOI: 10.1016/j.ijrobp.2017.10.031

Metaplastic Breast Cancer: Practice Patterns, Outcomes, and the Role of Radiotherapy
Haque, W, Verma, V, Naik, N, Butler, EB & Teh, BS 2018, Annals of Surgical Oncology, pp. 1-9. DOI: 10.1245/s10434-017-6316-2

Practice Patterns and Outcomes in Elderly Stage I Non-Small-cell Lung Cancer: A 2004 to 2012 SEER Analysis
Dalwadi, SM, Szeja, SS, Bernicker, EH, Butler, EB, Teh, BS & Farach, AM 2017, Clinical Lung Cancer. DOI: 10.1016/j.cllc.2017.11.004

Utilization of Stereotactic Radiosurgery for Renal Cell Carcinoma Brain Metastases
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Clinical Genitourinary Cancer. DOI: 10.1016/j.clgc.2018.03.015

Renal cell carcinoma brain metastasis with pseudoprogression and radiation necrosis on nivolumab after previous treatment with stereotactic radiosurgery: An illustrative case report and review of the literature
Lewis, GD, Jonasch, E, Shah, AY, Fuller, GN, Farach, AM, Butler, EB & Teh, BS 2018, Practical Radiation Oncology. DOI: 10.1016/j.prro.2018.03.003

Adjuvant Management of Pathologic Node–Positive Disease After Definitive Surgery for Clinical T1-2 N0 Rectal Cancer
Polamraju, P, Haque, W, Verma, V, Wiederhold, L, Hatch, S, Butler, EB & Teh, BS 2018, Clinical Colorectal Cancer. DOI: 10.1016/j.clcc.2018.04.001

The long-term sequelae of palliative radiation therapy to lumbosacral spine using conventional PA-single portal technique
Hsiao, KY, Wang, HC, Fung, SH, Haque, W, Butler, EB & Teh, BS 2018, Practical Radiation Oncology. DOI: 10.1016/j.prro.2018.04.003

Cardiac mortality in limited-stage small cell lung cancer
Verma, V, Fakhreddine, MH, Haque, W, Butler, EB, Teh, BS & Simone, CB 2018, Radiotherapy and Oncology. DOI: 10.1016/j.radonc.2018.06.011

Management of pathologic node-positive disease following initial surgery for clinical T1-2 N0 esophageal cancer: patterns of care and outcomes from the national cancer data base
Haque, W, Verma, V, Bernicker, E, Butler, EB & Teh, BS 2017, Acta Oncologica, pp. 1-8. DOI: 10.1080/0284186X.2017.1409435

The role of adjuvant chemotherapy in locally advanced bladder cancer
Haque, W, Lewis, GD, Verma, V, Darcourt, JG, Butler, EB & Teh, BS 2017, Acta Oncologica, pp. 1-7. DOI: 10.1080/0284186X.2017.1415461