Edward Brian Butler, MD

Jim and Joan Harrell Chair in Radiation Oncology, Department of Radiation Oncology
Professor of Radiation Oncology, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

After completing his postdoctoral training in 1987, Dr. Butler returned to the Wilford Hall USAF Medical Center in San Antonio, Texas where he became both the Chief of Radiation Oncology and the Chief of Brachytherapy. He also joined the faculty at The University of Texas Health Science Center at San Antonio as a Clinical Assistant Professor that same year. Dr. Butler would later join the Baylor College of Medicine where he would eventually become a full professor and the Chief of Radiation Oncology for both the medical school and the VA Hospital. He became the Medical Director of Radiation Oncology at Methodist in 1991, and received his faculty appointment at the Weill Medical School in 2006.

Description of Research

Dr. Butler’s research centers on preclinical and clinical studies that combine radiation therapy and gene therapy for the treatment of prostate cancer. In recent years, he has extended these successful studies to other cancers, notably pancreatic cancer. His research interests also include three-dimensional reconstruction of body organs to assist in better localization of radiation therapy.

Areas Of Expertise

Radiation therapy Prostate cancer Gene therapy Pancreatic cancer Computer visualization techniques
Education & Training

Residency, Stanford School of Medicine
MD, Georgetown University
Patents

IMPLANTABLE NANOCHANNEL DELIVERY DEVICES

Patent Number: US2018125780, May 10 2018


IMPLANTABLE NANOCHANNEL DELIVERY DEVICES

Patent Number: WO2016187100, Nov 24 2016

Publications

Immune Cell Landscape of the Tumor Microenvironment in a Murine NSCLC Model Following Radiation and Immune Checkpoint Inhibition Therapies
Sprouse, ML, Wang, DK, Butler, EB, Grattoni, A & Filgueira, CS 2019, 2019 CSBC/PS-ON Annual Junior Investigator’s Meeting, Bethesda, United States, 8/22/19 - 8/23/19, .

Immune Cell Landscape of the Tumor Microenvironment Following Radiation and Immunotherapy
Sprouse, ML, Wang, DK, Butler, EB, Grattoni, A & Filgueira, CS 2019, 7th Annual Houston Methodist Cancer Symposium, Houston, United States, 8/16/19, .

Immune Cell Landscape of the Tumor Microenvironment Following Radiation and Immunotherapy
Sprouse, ML, Wang, DK, Butler, EB, Grattoni, A & Filgueira, CS 2019, 2019 MAPTA Summer Science Symposium, Houston, United States, 8/8/19 - 8/9/19, .

Pathologic nodal clearance and complete response following neoadjuvant chemoradiation for clinical N2 non-small cell lung cancer: Predictors and long-term outcomes
Haque, WM, Verma, V, Butler, EB & Teh, BS 2019, Lung Cancer, vol. 130, pp. 93-100. https://doi.org/10.1016/j.lungcan.2019.02.003

Postmastectomy radiation therapy for triple negative, node-negative breast cancer
Haque, WM, Verma, V, Farach, AM, Butler, EB & Teh, BS 2019, Radiotherapy and Oncology, vol. 132, pp. 48-54. https://doi.org/10.1016/j.radonc.2018.11.012

Outcomes of pleomorphic lobular carcinoma versus invasive lobular carcinoma
Haque, WM, Arms, A, Verma, V, Hatch, S, Brian Butler, E & Teh, BS 2019, Breast, vol. 43, pp. 67-73. https://doi.org/10.1016/j.breast.2018.11.007

Post-treatment mortality after definitive chemoradiotherapy versus trimodality therapy for locally advanced non-small cell lung cancer
Haque, WM, Verma, V, Butler, EB, Teh, BS & Rusthoven, CG 2019, Lung Cancer, vol. 127, pp. 76-83. https://doi.org/10.1016/j.lungcan.2018.11.026

Disparities in the Treatment and Outcome of Stage I Non–Small-Cell Lung Cancer in the 21st Century
Dalwadi, SM, Lewis, GD, Bernicker, EH, Butler, EB, Teh, BS & Farach, AM 2019, Clinical Lung Cancer. https://doi.org/10.1016/j.cllc.2018.11.004

Stereotactic radiosurgery for brain metastases from newly diagnosed small cell lung cancer: practice patterns and outcomes
Jiang, W, Haque, WM, Verma, V, Butler, EB & Teh, BS 2019, Acta Oncologica. https://doi.org/10.1080/0284186X.2018.1562207

The Role of Adjuvant Radiotherapy in the Treatment of Pleural Mesothelioma
Lewis, GD, Dalwadi, SM, Farach, AM, Butler, EB & Teh, BS 2019, Annals of Surgical Oncology. https://doi.org/10.1245/s10434-019-07235-9

Racial and Socioeconomic Disparities in the Delivery of Immunotherapy for Metastatic Melanoma in the United States
Haque, WM, Verma, V, Butler, EB & Teh, BS 2019, Journal of Immunotherapy. https://doi.org/10.1097/CJI.0000000000000264

Neoadjuvant stereotactic body radiation therapy for nonmetastatic pancreatic adenocarcinoma
Jiang, W, Haque, WM, Verma, V, Butler, EB & Teh, BS 2019, Acta Oncologica. https://doi.org/10.1080/0284186X.2019.1631472

Cancer related fatigue in prostate cancer
Randall, J, Haque, WM, Butler, EB & Teh, BS 2019, Translational Andrology and Urology, vol. 8, pp. S106-S108. https://doi.org/10.21037/tau.2018.12.06

Omission of radiation therapy following breast conservation in older (=70 years) women with T1-2N0 triple-negative breast cancer
Haque, WM, Verma, V, Hsiao, KY, Hatch, S, Arentz, C, Szeja, S, Schwartz, M, Niravath, PA, Bonefas, E, Miltenburg, D, Butler, EB & Teh, BS 2019, Breast Journal. https://doi.org/10.1111/tbj.13443

Trimodality therapy for esophageal cancer at high volume facilities is associated with improved postoperative outcomes and overall survival
Haque, WM, Verma, V, Butler, EB & Teh, BS 2019, Diseases of the Esophagus, vol. 32, no. 4. https://doi.org/10.1093/dote/doy067

Survival Outcomes and Patterns of Management for Anal Adenocarcinoma
Lewis, GD, Haque, WM, Butler, EB & Teh, BS 2019, Annals of Surgical Oncology. https://doi.org/10.1245/s10434-019-07202-4

The impact of molecular status on survival outcomes for invasive micropapillary carcinoma of the breast
Lewis, GD, Xing, Y, Haque, WM, Patel, T, Schwartz, MR, Chen, AC, Farach, AM, Hatch, SS, Butler, EB, Chang, JC & Teh, BS 2019, Breast Journal. https://doi.org/10.1111/tbj.13432

Short-term Mortality Associated with Definitive Chemoradiotherapy Versus Radical Cystectomy for Muscle-invasive Bladder Cancer
Haque, WM, Verma, V, Aghazadeh, M, Darcourt, J, Butler, EB & Teh, BS 2019, Clinical Genitourinary Cancer. https://doi.org/10.1016/j.clgc.2019.06.015

Sequencing of Chemotherapy and Radiotherapy for Newly Diagnosed Anaplastic Oligodendroglioma and Oligoastrocytoma
Ryckman, JM, Surkar, SM, Haque, WM, Butler, EB, Teh, BS & Verma, V 2019, American Journal of Clinical Oncology: Cancer Clinical Trials. https://doi.org/10.1097/COC.0000000000000511

Nanofluidic drug-eluting seed for sustained intratumoral immunotherapy for cancer treatment
Chua, CYX, Filgueira, CS & Grattoni, A 2018, SITC 33rd Annual Meeting, Washington DC, United States, 11/9/18 - 11/11/18, .

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