Bin S. Teh, MD, FACR, FASTRO, FACRO

Professor of Radiation Oncology, Academic Institute
Full Member, Research Institute
Jim and Joan Harrell Centennial Chair in Radiation Oncology, Houston Methodist
Weill Cornell Medical College


Biography

Dr. Teh is a professor and vice chair of the Department of Radiation Oncology at Houston Methodist Hospital and Weill Medical School of Cornell. Dr. Teh has contributed significantly to the field of radiation oncology – encompassing radiotherapy technology, radiation physics, molecular radiobiology and the translation of advances in these areas to clinical use. He has been instrumental in pioneering new technology in radiation oncology including APBI (accelerated partial breast irradiation), IMRT (intensity-modulated radiation therapy), IGRT (image-guided radiation therapy), SBRT (stereotactic body radiation therapy), SRS (stereotactic radiosurgery), brachytherapy as well as combined radiotherapy and gene therapy. Dr. Teh treated the first breast cancer patient in Houston with multi-lumen catheter (Contura) high dose rate brachytherapy for partial breast irradiation. This is a short course of five days irradiation, as compared to the conventional six weeks irradiation for breast cancer. Partial breast irradiation is a novel approach to spare more normal tissues.

Dr. Teh earned his medical degree from the University of Queensland in Queensland, Australia. He completed his Radiation Oncology residency, training and fellowship in IMRT at the Baylor College of Medicine in Houston, Texas. Dr. Teh is active in ASTRO (American Society of Therapeutic Radiology and Oncology), RSNA (Radiological Society of North America and ARS (American Radium Society). He is the principal investigator for RTOG (Radiation Therapy Oncology Group) at Houston Methodist Hospital. Dr. Teh has published more than 100 peer-reviewed articles on topics such as IMRT for breast cancer, editorials, 15 book chapters and a textbook on PET-CT in radiotherapy. He plays an important role in breast cancer patient care, clinical research and the education of residents and students.

Description of Research

Dr. Teh’s research focuses on the treatment of genito-urinary malignancies and unlocking the myth of radio-resistance in cancers especially renal cell carcinoma. Other research interests include Intensity modulated radiation therapy (IMRT) for prostate cancer, head and neck cancer, central nervous system tumor, pediatric cancer and breast cancer, stereotactic radiosurgery (SRS), stereotactic body radiotherapy (SBRT), stereotactic radiation therapy (SRT) and image-guided radiation therapy (IGRT), brachytherapy for prostate cancer, breast cancer and endobronchial tumors, SRS and SBRT for primary and metastatic renal cell carcinoma as well as hepatocellular carcinoma, the role of combined radiotherapy and gene therapy for cancers including prostate cancer, renal cell carcinoma, bladder cancer, pancreatic cancer, glioblastoma multiforme, cervical cancer and head and neck cancer, combining targeted therapy (AKT-inhibitor, mTOR inhibitor, tyrosine kinase inhibitor) with radiotherapy for cancer treatment, and combining oncolytic virus with radiotherapy in overcoming radio-resistant tumors in oncology.

Areas Of Expertise

Cancer stem cells Radio-resistance Prostate Movement study Post-prostatectomy IMRT Gene expression profiling in cancer Proteomics in oncology
Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship, Baylor College of Medicine
MD, University of Queensland
Publications

Approach to radiation therapy in the Jehovah's Witness patient: An overview
Jurica, JM, Messer, JA, Teh, BS, Butler, EB & Farach, AM 2020, , Reports of Practical Oncology and Radiotherapy, vol. 25, no. 6, pp. 856-859. https://doi.org/10.1016/j.rpor.2020.08.014

Emerging treatment strategies for breast cancer brain metastasis: from translational therapeutics to real-world experience
Ren, D, Cheng, H, Wang, X, Vishnoi, M, Teh, BS, Rostomily, R, Chang, JC, Wong, ST & Zhao, H 2020, , Therapeutic Advances in Medical Oncology, vol. 12. https://doi.org/10.1177/1758835920936151

Early evidence of pulmonary dysfunction in survivors of childhood Hodgkin lymphoma
Agrusa, JE, Kothari, VD, Brown, AL, Masand, PM, Lewis, GD, Teh, BS, Paulino, AC, Silva-Carmona, MD, Melicoff, E, Allen, CE & Gramatges, MM 2020, , Leukemia and Lymphoma, vol. 61, no. 10, pp. 1-9. https://doi.org/10.1080/10428194.2020.1772478

Prognostic role of chemotherapy, radiotherapy dose, and extent of surgical resection in adult medulloblastoma
Haque, W, Verma, V, Brian Butler, E & Teh, BS 2020, , Journal of Clinical Neuroscience, vol. 76, pp. 154-160. https://doi.org/10.1016/j.jocn.2020.04.002

Practice Patterns for the Treatment of Uveal Melanoma with Iodine-125 Plaque Brachytherapy: Ocular Oncology Study Consortium Report 5
Binder, C, Mruthyunjaya, P, Schefler, AC, Seider, MI, Crilly, R, Hung, A, Meltsner, S, Mowery, Y, Kirsch, DG, Teh, BS, Jennelle, RLS, Studenski, MT, Liu, W, Lee, C, Hayman, JA, Kastner, B, Hadsell, M & Skalet, AH 2020, , Ocular Oncology and Pathology, vol. 6, no. 3, pp. 210-218. https://doi.org/10.1159/000504312

Clinical presentation, national practice patterns, and outcomes of breast adenomyoepithelioma
Haque, WM, Verma, V, Suzanne Klimberg, V, Nangia, J, Schwartz, M, Butler, EB & Teh, BS 2020, Breast Journal, vol. 26, no. 4, pp. 653-660. https://doi.org/10.1111/tbj.13638

Patterns of management and outcomes of unifocal versus multifocal glioblastoma
Haque, W, Thong, Y, Verma, V, Rostomily, R, Butler, EB & Teh, BS 2020, , Journal of Clinical Neuroscience, vol. 74, pp. 155-159. https://doi.org/10.1016/j.jocn.2020.01.086

Post-treatment mortality after definitive chemoradiotherapy versus resection for esophageal cancer
Jiang, W, Verma, V, Haque, W, Moreno, AC, Koshy, M, Butler, EB & Teh, BS 2020, Diseases of the Esophagus, vol. 33, no. 4. https://doi.org/10.1093/dote/doz073

Comparison of outcomes between metaplastic and triple-negative breast cancer patients
Polamraju, P, Haque, W, Cao, K, Verma, V, Schwartz, M, Klimberg, VS, Hatch, S, Niravath, P, Butler, EB & Teh, BS 2020, , Breast, vol. 49, pp. 8-16. https://doi.org/10.1016/j.breast.2019.10.003

Reply to Francesco Montorsi, Alessandro Larcher, and Umberto Capitanio's Letter to the Editor re: Rohann J.M. Correa, Alexander V. Louie, Nicholas G. Zaorsky, et al. The Emerging Role of Stereotactic Ablative Radiotherapy for Primary Renal Cell Carcinoma: A Systematic Review and Meta-Analysis. Eur Urol Focus. 2019 Jun 24. pii: S2405-4569(19)30157-9. https://doi.org/10.1016/j.euf.2019.06.002. [Epub ahead of print]
Correa, RJM, Louie, AV, Zaorsky, NG, Lehrer, EJ, Ellis, R, Ponsky, L, Kaplan, I, Mahadevan, A, Chu, W, Swaminath, A, Hannan, R, Onishi, H, Teh, BS, Muacevic, A, Lo, SS, Staehler, M & Siva, S 2020, , European Urology Focus. https://doi.org/10.1016/j.euf.2019.10.004

Controversies in the Management of Solid Tumor Bone Metastases
Farach, AM, Butler, EB & Teh, BS 2020, . in Medical Radiology. Medical Radiology, Springer, pp. 241-253. https://doi.org/10.1007/174_2019_217

Stereotactic Ablative Radiotherapy for =T1b Primary Renal Cell Carcinoma: A Report From the International Radiosurgery Oncology Consortium for Kidney (IROCK)
Siva, S, Correa, RJM, Warner, A, Staehler, M, Ellis, RJ, Ponsky, L, Kaplan, ID, Mahadevan, A, Chu, W, Gandhidasan, S, Swaminath, A, Onishi, H, Teh, BS, Lo, SS, Muacevic, A & Louie, AV 2020, , International Journal of Radiation Oncology Biology Physics, vol. 108, no. 4, pp. 941-949. https://doi.org/10.1016/j.ijrobp.2020.06.014

Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1
Liu, HC, Viswanath, DI, Pesaresi, F, Xu, Y, Zhang, L, Di Trani, N, Paez-Mayorga, J, Hernandez, N, Wang, Y, Erm, DR, Ho, J, Susnjar, A, Liu, X, Demaria, S, Chen, SH, Teh, BS, Butler, EB, Xuan Chua, CY & Grattoni, A 2020, , International Journal of Radiation Oncology Biology Physics. https://doi.org/10.1016/j.ijrobp.2020.07.2326

Eye plaque brachytherapy versus enucleation for ocular melanoma: an analysis from the National Cancer Database
Messer, JA, Zuhour, RJ, Haque, W, Lewis, GD, Schefler, AC, Wong, A, Bernicker, EH, Chevez-Barrios, P, Michelle Quan, E, Farach, A, Butler, EB, Hatch, SS & Teh, BS 2020, , Journal of Contemporary Brachytherapy, vol. 12, no. 4, pp. 303-310. https://doi.org/10.5114/jcb.2020.98108

Neoadjuvant radiation therapy for esophageal cancer: Is a higher dose better?
Haque, W, Butler, EB & Teh, BS 2019, Journal of Thoracic Disease, vol. 11, no. 12, pp. 5631-5634. https://doi.org/10.21037/jtd.2019.11.77

Lomustine and temozolomide for newly diagnosed glioblastoma with methylated MGMT promoter: Lessons from the CeTeG/NOA-09 trial
Tremont-Lukats, IW & Teh, BS 2019, Translational Cancer Research, vol. 8, pp. S589-S591. https://doi.org/10.21037/tcr.2019.06.43

ASO Author Reflections: Optimal Management of Anal Adenocarcinoma: Clues from a Large, National Database
Lewis, GD & Teh, BS 2019, Annals of Surgical Oncology, vol. 26. https://doi.org/10.1245/s10434-019-07466-w

Toxicity of pelvic nodal radiation for localized prostate cancer
Haque, W, Butler, EB & Teh, BS 2019, Annals of translational medicine, vol. 7, no. Suppl 8, pp. S359. https://doi.org/10.21037/atm.2019.09.57

ASO Author Reflections: Postoperative Radiotherapy for Patients with Mesothelioma—Past, Present, and Future
Lewis, GD & Teh, BS 2019, Annals of Surgical Oncology, vol. 26, pp. 635-636. https://doi.org/10.1245/s10434-019-07467-9

Co-registration of MR and FDG-PET imaging for stereotactic radiotherapy planning; case report in a previously irradiated brain metastasis with recurrent tumor and radiation necrosis
Scranton, RA, Sadrameli, S, Butler, EB, Farach, A, Wang, H-C, Teh, BS, Tremont-Lukats, IW, Fung, SH, Zanotti-Fregonara, P & Rostomily, RC 2019, , Practical Radiation Oncology. https://doi.org/10.1016/j.prro.2019.11.008