Bin S. Teh, MD, FACR, FASTRO, FACRO

Professor of Radiation Oncology, Institute for Academic Medicine
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Teh is a professor and vice chair of the Department of Radiation Oncology at Houston Methodist Hospital and Weill Medical School of Cornell. Dr. Teh has contributed significantly to the field of radiation oncology – encompassing radiotherapy technology, radiation physics, molecular radiobiology and the translation of advances in these areas to clinical use. He has been instrumental in pioneering new technology in radiation oncology including APBI (accelerated partial breast irradiation), IMRT (intensity-modulated radiation therapy), IGRT (image-guided radiation therapy), SBRT (stereotactic body radiation therapy), SRS (stereotactic radiosurgery), brachytherapy as well as combined radiotherapy and gene therapy. Dr. Teh treated the first breast cancer patient in Houston with multi-lumen catheter (Contura) high dose rate brachytherapy for partial breast irradiation. This is a short course of five days irradiation, as compared to the conventional six weeks irradiation for breast cancer. Partial breast irradiation is a novel approach to spare more normal tissues.

Dr. Teh earned his medical degree from the University of Queensland in Queensland, Australia. He completed his Radiation Oncology residency, training and fellowship in IMRT at the Baylor College of Medicine in Houston, Texas. Dr. Teh is active in ASTRO (American Society of Therapeutic Radiology and Oncology), RSNA (Radiological Society of North America and ARS (American Radium Society). He is the principal investigator for RTOG (Radiation Therapy Oncology Group) at Houston Methodist Hospital. Dr. Teh has published more than 100 peer-reviewed articles on topics such as IMRT for breast cancer, editorials, 15 book chapters and a textbook on PET-CT in radiotherapy. He plays an important role in breast cancer patient care, clinical research and the education of residents and students.

Description of Research

Dr. Teh’s research focuses on the treatment of genito-urinary malignancies and unlocking the myth of radio-resistance in cancers especially renal cell carcinoma. Other research interests include Intensity modulated radiation therapy (IMRT) for prostate cancer, head and neck cancer, central nervous system tumor, pediatric cancer and breast cancer, stereotactic radiosurgery (SRS), stereotactic body radiotherapy (SBRT), stereotactic radiation therapy (SRT) and image-guided radiation therapy (IGRT), brachytherapy for prostate cancer, breast cancer and endobronchial tumors, SRS and SBRT for primary and metastatic renal cell carcinoma as well as hepatocellular carcinoma, the role of combined radiotherapy and gene therapy for cancers including prostate cancer, renal cell carcinoma, bladder cancer, pancreatic cancer, glioblastoma multiforme, cervical cancer and head and neck cancer, combining targeted therapy (AKT-inhibitor, mTOR inhibitor, tyrosine kinase inhibitor) with radiotherapy for cancer treatment, and combining oncolytic virus with radiotherapy in overcoming radio-resistant tumors in oncology.

Areas Of Expertise

Cancer stem cells Radio-resistance Prostate Movement study Post-prostatectomy IMRT Gene expression profiling in cancer Proteomics in oncology
Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship, Baylor College of Medicine
MD, University of Queensland
Publications

Utilization of Stereotactic Radiosurgery for Renal Cell Carcinoma Brain Metastases
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Clinical Genitourinary Cancer. DOI: 10.1016/j.clgc.2018.03.015

Response rates and pathologic complete response by breast cancer molecular subtype following neoadjuvant chemotherapy
Haque, W, Verma, V, Hatch, S, Suzanne Klimberg, V, Brian Butler, E & Teh, BS 2018, Breast Cancer Research and Treatment, pp. 1-9. DOI: 10.1007/s10549-018-4801-3

Omission of radiotherapy in elderly women with early stage metaplastic breast cancer
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Breast, vol 38, pp. 154-159. DOI: 10.1016/j.breast.2018.01.005

Utilization of radiotherapy and stereotactic body radiation therapy for renal cell cancer in the USA
Haque, W, Verma, V, Lewis, GD, Lo, SS, Butler, EB & Teh, BS 2018, Future Oncology, vol 14, no. 9, pp. 819-827. DOI: 10.2217/fon-2017-0536

Utilization of neoadjuvant intensity-modulated radiation therapy and proton beam therapy for esophageal cancer in the United States
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Journal of Gastrointestinal Oncology, vol 9, no. 2, pp. 282-294. DOI: 10.21037/jgo.2017.11.14

The impact of comorbidity on overall survival in elderly nasopharyngeal carcinoma patients: A National Cancer Data Base analysis
Huang, Y, Chen, W, Haque, W, Verma, V, Xing, Y, Teh, BS & Brian Butler, E 2018, Cancer Medicine. DOI: 10.1002/cam4.1377

Radiation Oncology in the Face of Natural Disaster: The Experience of Houston Methodist Hospital
Mireles, M, Pino, R, Teh, BS, Farach, A, Joseph, A & Butler, EB 2018, International Journal of Radiation Oncology Biology Physics, vol 100, no. 4, pp. 813-815. DOI: 10.1016/j.ijrobp.2017.12.002

Clinical benefit to regionalization of care for muscle invasive bladder cancer
Haque, W, Butler, EB & Teh, BS 2018, Translational Andrology and Urology, vol 7, pp. S98-S100. DOI: 10.21037/tau.2018.01.05

Radiation dose in neoadjuvant chemoradiation therapy for esophageal cancer: Patterns of care and outcomes from the National Cancer Data Base
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, Journal of Gastrointestinal Oncology, vol 9, no. 1, pp. 80-89. DOI: 10.21037/jgo.2017.09.12

Trends in Cardiac Mortality in Patients With Locally Advanced Non-Small Cell Lung Cancer
Haque, W, Verma, V, Fakhreddine, M, Butler, EB, Teh, BS & Simone, CB 2018, International Journal of Radiation Oncology Biology Physics, vol 100, no. 2, pp. 470-477. DOI: 10.1016/j.ijrobp.2017.10.031

Metaplastic Breast Cancer: Practice Patterns, Outcomes, and the Role of Radiotherapy
Haque, W, Verma, V, Naik, N, Butler, EB & Teh, BS 2018, Annals of Surgical Oncology, pp. 1-9. DOI: 10.1245/s10434-017-6316-2

The role of adjuvant chemotherapy in locally advanced bladder cancer
Haque, W, Lewis, GD, Verma, V, Darcourt, JG, Butler, EB & Teh, BS 2017, Acta Oncologica, pp. 1-7. DOI: 10.1080/0284186X.2017.1415461

Practice Patterns and Outcomes in Elderly Stage I Non-Small-cell Lung Cancer: A 2004 to 2012 SEER Analysis
Dalwadi, SM, Szeja, SS, Bernicker, EH, Butler, EB, Teh, BS & Farach, AM 2017, Clinical Lung Cancer. DOI: 10.1016/j.cllc.2017.11.004

Patterns of Care and Outcomes of Hypofractionated Chemoradiation Versus Conventionally Fractionated Chemoradiation for Glioblastoma in the Elderly Population
Haque, W, Verma, V, Butler, EB & Teh, BS 2018, American Journal of Clinical Oncology: Cancer Clinical Trials, vol 41, no. 2, pp. 167-172. DOI: 10.1097/COC.0000000000000417

Management of pathologic node-positive disease following initial surgery for clinical T1-2 N0 esophageal cancer: patterns of care and outcomes from the national cancer data base
Haque, W, Verma, V, Bernicker, E, Butler, EB & Teh, BS 2017, Acta Oncologica, pp. 1-8. DOI: 10.1080/0284186X.2017.1409435

Addition of chemotherapy to hypofractionated radiotherapy for glioblastoma: practice patterns, outcomes, and predictors of survival
Haque, W, Verma, V, Butler, EB & Teh, BS 2017, Journal of Neuro-Oncology, pp. 1-9. DOI: 10.1007/s11060-017-2654-y

National Practice Patterns and Outcomes for T4b Urothelial Cancer of the Bladder
Haque, W, Verma, V, Butler, EB & Teh, BS 2017, Clinical Genitourinary Cancer. DOI: 10.1016/j.clgc.2017.08.013

Treatment Outcomes and Prognostic Factors in Male Patients With Stage IV Breast Cancer: A Population-based Study
Chen, W, Huang, Y, Lewis, GD, Szeja, SS, Hatch, SS, Farach, A, Miltenburg, D, Butler, EB, Chang, JC & Teh, BS 2017, Clinical Breast Cancer. DOI: 10.1016/j.clbc.2017.07.005

Radiation therapy utilization and outcomes for older women with breast cancer: Impact of molecular subtype and tumor grade
Haque, W, Kee Yuan, DM, Verma, V, Butler, EB, Teh, BS, Wiederhold, L & Hatch, S 2017, Breast, vol 35, pp. 34-41. DOI: 10.1016/j.breast.2017.06.011

Radical cystectomy versus chemoradiation for muscle-invasive bladder cancer: Impact of treatment facility and sociodemographics
Haque, W, Verma, V, Butler, EB & Teh, BS 2017, Anticancer Research, vol 37, no. 10, pp. 5603-5608. DOI: 10.21873/anticanres.11994