Bin S. Teh, MD, FACR, FASTRO, FACRO

Professor of Radiation Oncology, Institute for Academic Medicine
Full Member, Research Institute
Jim and Joan Harrell Centennial Chair in Radiation Oncology, Houston Methodist
Weill Cornell Medical College


Biography

Dr. Teh is a professor and vice chair of the Department of Radiation Oncology at Houston Methodist Hospital and Weill Medical School of Cornell. Dr. Teh has contributed significantly to the field of radiation oncology – encompassing radiotherapy technology, radiation physics, molecular radiobiology and the translation of advances in these areas to clinical use. He has been instrumental in pioneering new technology in radiation oncology including APBI (accelerated partial breast irradiation), IMRT (intensity-modulated radiation therapy), IGRT (image-guided radiation therapy), SBRT (stereotactic body radiation therapy), SRS (stereotactic radiosurgery), brachytherapy as well as combined radiotherapy and gene therapy. Dr. Teh treated the first breast cancer patient in Houston with multi-lumen catheter (Contura) high dose rate brachytherapy for partial breast irradiation. This is a short course of five days irradiation, as compared to the conventional six weeks irradiation for breast cancer. Partial breast irradiation is a novel approach to spare more normal tissues.

Dr. Teh earned his medical degree from the University of Queensland in Queensland, Australia. He completed his Radiation Oncology residency, training and fellowship in IMRT at the Baylor College of Medicine in Houston, Texas. Dr. Teh is active in ASTRO (American Society of Therapeutic Radiology and Oncology), RSNA (Radiological Society of North America and ARS (American Radium Society). He is the principal investigator for RTOG (Radiation Therapy Oncology Group) at Houston Methodist Hospital. Dr. Teh has published more than 100 peer-reviewed articles on topics such as IMRT for breast cancer, editorials, 15 book chapters and a textbook on PET-CT in radiotherapy. He plays an important role in breast cancer patient care, clinical research and the education of residents and students.

Description of Research

Dr. Teh’s research focuses on the treatment of genito-urinary malignancies and unlocking the myth of radio-resistance in cancers especially renal cell carcinoma. Other research interests include Intensity modulated radiation therapy (IMRT) for prostate cancer, head and neck cancer, central nervous system tumor, pediatric cancer and breast cancer, stereotactic radiosurgery (SRS), stereotactic body radiotherapy (SBRT), stereotactic radiation therapy (SRT) and image-guided radiation therapy (IGRT), brachytherapy for prostate cancer, breast cancer and endobronchial tumors, SRS and SBRT for primary and metastatic renal cell carcinoma as well as hepatocellular carcinoma, the role of combined radiotherapy and gene therapy for cancers including prostate cancer, renal cell carcinoma, bladder cancer, pancreatic cancer, glioblastoma multiforme, cervical cancer and head and neck cancer, combining targeted therapy (AKT-inhibitor, mTOR inhibitor, tyrosine kinase inhibitor) with radiotherapy for cancer treatment, and combining oncolytic virus with radiotherapy in overcoming radio-resistant tumors in oncology.

Areas Of Expertise

Cancer stem cells Radio-resistance Prostate Movement study Post-prostatectomy IMRT Gene expression profiling in cancer Proteomics in oncology
Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship, Baylor College of Medicine
MD, University of Queensland
Publications

Comparison of outcomes between metaplastic and triple-negative breast cancer patients
Polamraju, P, Haque, WM, Cao, K, Verma, V, Schwartz, M, Klimberg, VS, Hatch, S, Niravath, PA, Butler, EB & Teh, BS 2020, Breast, vol. 49, pp. 8-16. https://doi.org/10.1016/j.breast.2019.10.003

Biopsy proven metastatic meningioma: A case report and review of the literature
Vakil, H, Tran, L, Lewis, GD, Cykowski, MD, Butler, EB & Teh, BS 2019, Reports of Practical Oncology and Radiotherapy, vol. 24, no. 6, pp. 528-532. https://doi.org/10.1016/j.rpor.2019.08.002

Socioeconomic Factors Associated with Lack of Treatment in Early Stage Non-Small Cell Lung Cancer
Dalwadi, SM, Zhang, J, Bernicker, EH, Butler, EB, Teh, BS & Farach, AM 2019, Cancer Investigation, vol. 37, no. 9, pp. 506-511. https://doi.org/10.1080/07357907.2019.1666136

Prognosis of lymphotropic invasive micropapillary breast carcinoma analyzed by using data from the National Cancer Database
Lewis, GD, Xing, Y, Haque, WM, Patel, T, Schwartz, M, Chen, A, Farach, AM, Hatch, SS, Butler, EB, Chang, JC & Teh, BS 2019, Cancer Communications, vol. 39, no. 1, 60. https://doi.org/10.1186/s40880-019-0406-4

Stereotactic Radiotherapy as a Treatment Option for Renal Tumors in the Solitary Kidney: A Multicenter Analysis from the IROCK
Correa, RJM, Louie, AV, Staehler, M, Warner, A, Gandhidasan, S, Ponsky, L, Ellis, R, Kaplan, I, Mahadevan, A, Chu, W, Swaminath, A, Onishi, H, Teh, BS, Lo, SS, Muacevic, A & Siva, S 2019, The Journal of urology, vol. 201, no. 6, pp. 1097-1104. https://doi.org/10.1097/JU.0000000000000111

Patterns of End-of-Life Oncologic Care for Stage IV Non-small Cell Lung Cancer in the United States
Verma, V, Brian Butler, E, Teh, BS & Haque, WM 2019, Anticancer Research, vol. 39, no. 6, pp. 3137-3140. https://doi.org/10.21873/anticanres.13450

Enhanced dermatologic toxicity following concurrent treatment with palbociclib and radiation therapy: A case report
Messer, JA, Ekinci, E, Patel, TA & Teh, BS 2019, Reports of Practical Oncology and Radiotherapy, vol. 24, no. 3, pp. 276-280. https://doi.org/10.1016/j.rpor.2019.03.001

Pathologic nodal clearance and complete response following neoadjuvant chemoradiation for clinical N2 non-small cell lung cancer: Predictors and long-term outcomes
Haque, WM, Verma, V, Butler, EB & Teh, BS 2019, Lung Cancer, vol. 130, pp. 93-100. https://doi.org/10.1016/j.lungcan.2019.02.003

Postmastectomy radiation therapy for triple negative, node-negative breast cancer
Haque, WM, Verma, V, Farach, AM, Butler, EB & Teh, BS 2019, Radiotherapy and Oncology, vol. 132, pp. 48-54. https://doi.org/10.1016/j.radonc.2018.11.012

The Value of Surgical Exposure in Radiation Oncology Training
Dalwadi, SM, Teh, BS & Love, JD 2019, International Journal of Radiation Oncology Biology Physics, vol. 103, no. 3, pp. 775. https://doi.org/10.1016/j.ijrobp.2018.10.019

Outcomes of pleomorphic lobular carcinoma versus invasive lobular carcinoma
Haque, WM, Arms, A, Verma, V, Hatch, S, Brian Butler, E & Teh, BS 2019, Breast, vol. 43, pp. 67-73. https://doi.org/10.1016/j.breast.2018.11.007

Reply to the letter “Pure or mixed type invasive lobular carcinoma; are they different from each other?”
Haque, WM & Teh, BS 2019, Breast, vol. 43, pp. 151-152. https://doi.org/10.1016/j.breast.2018.12.006

Sequencing of Chemotherapy and Radiotherapy for Newly Diagnosed Anaplastic Oligodendroglioma and Oligoastrocytoma
Ryckman, JM, Surkar, SM, Haque, WM, Butler, EB, Teh, BS & Verma, V 2019, American Journal of Clinical Oncology: Cancer Clinical Trials. https://doi.org/10.1097/COC.0000000000000511

Post-treatment mortality after definitive chemoradiotherapy versus trimodality therapy for locally advanced non-small cell lung cancer
Haque, WM, Verma, V, Butler, EB, Teh, BS & Rusthoven, CG 2019, Lung Cancer, vol. 127, pp. 76-83. https://doi.org/10.1016/j.lungcan.2018.11.026

Disparities in the Treatment and Outcome of Stage I Non–Small-Cell Lung Cancer in the 21st Century
Dalwadi, SM, Lewis, GD, Bernicker, EH, Butler, EB, Teh, BS & Farach, AM 2019, Clinical Lung Cancer. https://doi.org/10.1016/j.cllc.2018.11.004

Stereotactic radiosurgery for brain metastases from newly diagnosed small cell lung cancer: practice patterns and outcomes
Jiang, W, Haque, WM, Verma, V, Butler, EB & Teh, BS 2019, Acta Oncologica. https://doi.org/10.1080/0284186X.2018.1562207

Survival Outcomes and Patterns of Management for Anal Adenocarcinoma
Lewis, GD, Haque, WM, Butler, EB & Teh, BS 2019, Annals of Surgical Oncology. https://doi.org/10.1245/s10434-019-07202-4

The Role of Adjuvant Radiotherapy in the Treatment of Pleural Mesothelioma
Lewis, GD, Dalwadi, SM, Farach, AM, Butler, EB & Teh, BS 2019, Annals of Surgical Oncology. https://doi.org/10.1245/s10434-019-07235-9

ASO Author Reflections: Optimal Management of Anal Adenocarcinoma: Clues from a Large, National Database
Lewis, GD & Teh, BS 2019, Annals of Surgical Oncology. https://doi.org/10.1245/s10434-019-07466-w

The Emerging Role of Stereotactic Ablative Radiotherapy for Primary Renal Cell Carcinoma: A Systematic Review and Meta-Analysis
Correa, RJM, Louie, AV, Zaorsky, NG, Lehrer, EJ, Ellis, R, Ponsky, L, Kaplan, I, Mahadevan, A, Chu, W, Hannan, R, Onishi, H, Teh, BS, Muacevic, A, Lo, SS, Staehler, M & Siva, S 2019, European Urology Focus. https://doi.org/10.1016/j.euf.2019.06.002

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