Assaf Zinger, PhD

Adjunct Assistant Professor of Cardiovascular Sciences, Academic Institute
Adjunct Assistant Professor of Neurosurgery, Academic Institute
Houston Methodist


Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice
Baudo, G, Flinn, H, Holcomb, M, Tiwari, A, Soriano, S, Taraballi, F, Godin, B, Zinger, A & Villapol, S 2024, , Bioengineering and Translational Medicine. https://doi.org/10.1002/btm2.10647

Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications
Zinger, A 2023, , Journal of Controlled Release, vol. 358, pp. 591-600. https://doi.org/10.1016/j.jconrel.2023.04.040

Harnessing RNA Technology to Advance Therapeutic Vaccine Antigens against Chagas Disease
Mancino, C, Pollet, J, Zinger, A, Jones, KM, Villar, MJ, Leao, AC, Adhikari, R, Versteeg, L, Tyagi Kundu, R, Strych, U, Giordano, F, Hotez, PJ, Bottazzi, ME, Taraballi, F & Poveda, C 2024, , ACS Applied Materials and Interfaces, vol. 16, no. 13, 3c18830, pp. 15832–15846. https://doi.org/10.1021/acsami.3c18830

Zinger, AY & Taraballi, F Sep. 08 2022, , Patent No. US2022280428.

LDL-Based Lipid Nanoparticle Derived for Blood Plasma Accumulates Preferentially in Atherosclerotic Plaque
Boada, CA, Zinger, A, Rohen, S, Martinez, JO, Evangelopoulos, M, Molinaro, R, Lu, M, Villarreal-Leal, RA, Giordano, F, Sushnitha, M, De Rosa, E, Simonsen, JB, Shevkoplyas, S, Taraballi, F & Tasciotti, E 2021, , Frontiers in Bioengineering and Biotechnology, vol. 9, 794676. https://doi.org/10.3389/fbioe.2021.794676

Biomimetic Nanoparticles as a Theranostic Tool for Traumatic Brain Injury
Zinger, A, Soriano, S, Baudo, G, De Rosa, E, Taraballi, F & Villapol, S 2021, , Advanced Functional Materials, vol. 31, no. 30, pp. 2100722. https://doi.org/10.1002/adfm.202100722

Artificially Intelligent Nanoarray Detects Various Cancers by Liquid Biopsy of Volatile Markers
Einoch Amor, R, Zinger, A, Broza, YY, Schroeder, A & Haick, H 2022, , Advanced Healthcare Materials, vol. 11, no. 17, 2200356, pp. e2200356. https://doi.org/10.1002/adhm.202200356

Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility
Poley, M, Mora-Raimundo, P, Shammai, Y, Kaduri, M, Koren, L, Adir, O, Shklover, J, Shainsky-Roitman, J, Ramishetti, S, Man, F, De Rosales, RTM, Zinger, A, Peer, D, Ben-Aharon, I & Schroeder, A 2022, , ACS Nano, vol. 16, no. 4, pp. 5246-5257. https://doi.org/10.1021/acsnano.1c07237

Humanized Biomimetic Nanovesicles for Neuron Targeting
Zinger, A, Cvetkovic, C, Sushnitha, M, Naoi, T, Baudo, G, Anderson, M, Shetty, A, Basu, N, Covello, J, Tasciotti, E, Amit, M, Xie, T, Taraballi, F & Krencik, R 2021, , Advanced Science, vol. 8, no. 19, 2101437, pp. e2101437. https://doi.org/10.1002/advs.202101437

Humanized Biomimetic Nanovesicles for Neuron Targeting
Zinger, A, Cvetkovic, C, Sushnitha, M, Naoi, T, Baudo, G, Anderson, M, Shetty, A, Basu, N, Covello, J, Tasciotti, E, Amit, M, Xie, T, Taraballi, F & Krencik, R 2021, , Advanced Science, vol. 8, no. 19, 2101437. https://doi.org/10.1002/advs.202101437

Intravital imaging of vascular anomalies and extracellular matrix remodeling in orthotopic pancreatic tumors
Bochner, F, Mohan, V, Zinger, A, Golani, O, Schroeder, A, Sagi, I & Neeman, M 2020, , International Journal of Cancer, vol. 146, no. 8, pp. 2209-2217. https://doi.org/10.1002/ijc.32759

Loss of p53 drives neuron reprogramming in head and neck cancer
Amit, M, Takahashi, H, Dragomir, MP, Lindemann, A, Gleber-Netto, FO, Pickering, CR, Anfossi, S, Osman, AA, Cai, Y, Wang, R, Knutsen, E, Shimizu, M, Ivan, C, Rao, X, Wang, J, Silverman, DA, Tam, S, Zhao, M, Caulin, C, Zinger, A, Tasciotti, E, Dougherty, PM, El-Naggar, A, Calin, GA & Myers, JN 2020, , Nature, vol. 578, no. 7795, pp. 449-454. https://doi.org/10.1038/s41586-020-1996-3

Leukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma
Molinaro, R, Martinez, JO, Zinger, A, De Vita, A, Storci, G, Arrighetti, N, De Rosa, E, Hartman, KA, Basu, N, Taghipour, N, Corbo, C & Tasciotti, E 2020, , Biomaterials Science, vol. 8, no. 1, pp. 333-341. https://doi.org/10.1039/c9bm01766f

Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors
Zinger, A, Koren, L, Adir, O, Poley, M, Alyan, M, Yaari, Z, Noor, N, Krinsky, N, Simon, A, Gibori, H, Krayem, M, Mumblat, Y, Kasten, S, Ofir, S, Fridman, E, Milman, N, Lübtow, MM, Liba, L, Shklover, J, Shainsky-Roitman, J, Binenbaum, Y, Hershkovitz, D, Gil, Z, Dvir, T, Luxenhofer, R, Satchi-Fainaro, R & Schroeder, A 2019, , ACS Nano, vol. 13, no. 10, pp. 11008-11021. https://doi.org/10.1021/acsnano.9b02395

Tailoring the lipid composition of nanoparticles modulates their cellular uptake and affects the viability of triple negative breast cancer cells
Abumanhal-Masarweh, H, da Silva, D, Poley, M, Zinger, A, Goldman, E, Krinsky, N, Kleiner, R, Shenbach, G, Schroeder, JE, Shklover, J, Shainsky-Roitman, J & Schroeder, A 2019, , Journal of Controlled Release, vol. 307, pp. 331-341. https://doi.org/10.1016/j.jconrel.2019.06.025

Macrophage-derived nanovesicles exert intrinsic anti-inflammatory properties and prolong survival in sepsis through a direct interaction with macrophages
Molinaro, R, Pastò, A, Corbo, C, Taraballi, F, Giordano, F, Martinez, JO, Zhao, P, Wang, X, Zinger, A, Boada, C, Hartman, KA & Tasciotti, E 2019, , Nanoscale, vol. 11, no. 28, pp. 13576-13586. https://doi.org/10.1039/c9nr04253a

Sodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin
Abumanhal-Masarweh, H, Koren, L, Zinger, A, Yaari, Z, Krinsky, N, Kaneti, G, Dahan, N, Lupu-Haber, Y, Suss-Toby, E, Weiss-Messer, E, Schlesinger-Laufer, M, Shainsky-Roitman, J & Schroeder, A 2019, , Journal of Controlled Release, vol. 296, pp. 1-13. https://doi.org/10.1016/j.jconrel.2019.01.004

Therapeutic nanoparticles penetrate leaves and deliver nutrients to agricultural crops
Karny, A, Zinger, A, Kajal, A, Shainsky-Roitman, J & Schroeder, A 2018, , Scientific Reports, vol. 8, no. 1, 7589. https://doi.org/10.1038/s41598-018-25197-y

Synthetic Cells Synthesize Therapeutic Proteins inside Tumors
Krinsky, N, Kaduri, M, Zinger, A, Shainsky-Roitman, J, Goldfeder, M, Benhar, I, Hershkovitz, D & Schroeder, A 2018, , Advanced Healthcare Materials, vol. 7, no. 9, 1701163. https://doi.org/10.1002/adhm.201701163

Proteolytic Nanoparticles Replace a Surgical Blade by Controllably Remodeling the Oral Connective Tissue
Zinger, A, Adir, O, Alper, M, Simon, A, Poley, M, Tzror, C, Yaari, Z, Krayem, M, Kasten, S, Nawy, G, Herman, A, Nir, Y, Akrish, S, Klein, T, Shainsky-Roitman, J, Hershkovitz, D & Schroeder, A 2018, , ACS Nano, vol. 12, no. 2, pp. 1482-1490. https://doi.org/10.1021/acsnano.7b07983