A. Osama Gaber, MD, FACS

J.C. Walter Jr. Presidential Distinguished Chair & Director, J.C. Walter Jr. Transplant Center
Professor of Surgery, Institute for Academic Medicine
Full Member, Research Institute
Program Director, Transplant Surgery Residency, Department of Surgery
Houston Methodist
Weill Cornell Medical College


Transplantation Surgery Fellowship


Biography

Dr. Gaber received his first academic appointment in 1987, as an Assistant Professor in the Department of Surgery at the University of Tennessee in Memphis. He became an Associate Professor there in 1991, and received his full professorship and was named to the Baptist Memorial Health Care Foundation chair of excellence in transplantation in 1994. While at the University of Tennessee, Dr. Gaber also held professorships in the Departments of Pharmacy and in the College of Nursing. He was also the Medical Director for the University of Tennessee Bowld Hospital, and the Methodist University Transplant Institute.

Dr. Gaber is a prolific researcher and has authored over 270 scientific papers, as well as more than 340 abstracts and numerous book chapters,and his research has been funded by numerous grants from the National Institutes of Health, the Juvenile Diabetes Research Foundation, and several national and local foundations. Dr. Gaber assumed his positions at the Houston Methodist Hospital and Research Institute in Houston in 2006.

Description of Research

While also conducting transplant immunotherapy research for liver and kidney whole organ transplants and allografts, the main focus of Dr. Gaber´s research is in the transplantation of islets to alleviate diabetic complications. He and his collaborators have developed the protocol for long term islet culture and described the clinical transplantation of islets through the intestinal veins. Dr. Gaber´s current studies center on the testing of gene therapy and other approaches to test for islet viability and assist the transplanted islets to develop a sustaining blood supply and resist rejection by the recipient´s immune system.

Areas Of Expertise

Diabetes Transplant immunotherapy Islet cells Cell isolation protocols Kidney transplant Pancreas transplant Liver transplant Kidney disorders
Education & Training

Clinical Fellowship, University of Chicago
Residency, Boston University Medical Center
Internship, Washington Hospital Center
MD, Ain Shams University School of Medicine
Publications

Pre-Transplant Serum Chemokines As Biomarkers for Prediction of Futility Following Liver Transplantation in High Acuity Recipients
Lunsford, KE, Moore, LW, Nguyen, DTM, Graviss, EA, Manner, CJ, Vyas, H, Thomas, JV, Minze, LJ, Dorman, SA, Saharia, A, Mobley, CM, Hobeika, MJ, Victor, III, DW, McFadden, RS, Gaber, AO, Li, XC & Ghobrial, RM 2018, American Association for the study of Liver Diseases - AASLD 2018, San Francisco, United States, 11/9/18 - 11/13/18, .

Survival and Recidivism in Patients Undergoing Early Liver Transplant for Acute Alcoholic Hepatitis: A Single Center Analysis
Thomas, JV, Lunsford, KE, Victor, III, DW, Theriot, L, Ontiveros, J, Nguyen, DTM, Graviss, EA, Saharia, A, Mobley, CM, Hobeika, MJ, Corkrean, J, Balogh, J, Galati, J, Ankoma-Sey, V, Egwim, C, Duchini, A, Li, XC, McFadden, RS, Monsour, Jr. HP, Gaber, AO & Ghobrial, RM 2018, American Association for the study of Liver Diseases - AASLD 2018, San Francisco, United States, 11/9/18 - 11/13/18, .

Variability in endocrine cell identity in patients with chronic pancreatitis undergoing islet auto-transplantation
Beamish, C, Gaber, AO, Afshar, S, Fraga, DW, Hamilton, DJ & Sabek, O 2018, American Journal of Transplantation.

Change in QTC Interval after Kidney Transplantation; Mechanisms and Outcomes
Lai, E, Acharya, V, Nguyen, DTM, Graviss, EA, Gaber, AO & Suki, WN 2018, Experimental and Clinical Transplantation, vol. 3, no. 121. DOI: 10.4172/2475-7640.1000121

Suitability of Estimated Glomerular Filtration Rate for Live Kidney Donor Selection
Akhimiona, CO, Nguyen, DT, Graviss, EA, Gaber, AO & Suki, WN 2018, Transplantation Proceedings. DOI: 10.1016/j.transproceed.2018.09.013

Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells
Farina, M, Chua, CYX, Ballerini, A, Thekkedath, U, Alexander, JF, Rhudy, JR, Torchio, G, Fraga, D, Pathak, RR, Villanueva, M, Shin, CS, Niles, JA, Sesana, R, Demarchi, D, Sikora, AG, Acharya, GS, Gaber, AO, Nichols, JE & Grattoni, A 2018, Biomaterials, vol. 177, pp. 125-138. DOI: 10.1016/j.biomaterials.2018.05.047

Liver transplantation for locally advanced intrahepatic cholangiocarcinoma – Authors' reply
Lunsford, KE, Javle, M, Gaber, AO, Vauthey, JN & Ghobrial, RM 2018, The Lancet Gastroenterology and Hepatology, vol. 3, no. 8, pp. 529-530. DOI: 10.1016/S2468-1253(18)30167-5

De Novo DSA in the Setting of Stable Renal Allograft Function is a Benign Finding
Knight, RJ, Eagar, TN, Nguyen, DTM, Graviss, EA, Kuten, SA, Patel, SJ, Moore, LW & Gaber, AO 2018, 27th International Congress of The Transplantation Society, Madrid, Spain, 6/30/18 - 7/5/18, .

Short- and midterm results for internal jugular vein extension for short right renal vein kidney transplant
Lu, T, Yi, SG, Bismuth, J, Knight, RJ, Gaber, AO & Bechara, CF 2018, Clinical Transplantation, vol. 32, no. 8, e13312, pp. e13312. DOI: 10.1111/ctr.13312

Ciprofloxacin for BK Viremia Prophylaxis in Kidney Transplant Recipients: Results of a Prospective, Randomized Controlled Trial
Patel, SJ, Nguyen, DTM, Graviss, EA, Nolte, JV, Agboli, I, Moore, LW, Kuten, SA, Pham, C, Gaber, AO & Knight, RJ 2018, 2018 American Transplant Congress (ATC), Seattle, United States, 6/2/18 - 6/6/18, .

Prevalence of Metabolic Syndrome (MetS) and Insulin Resistance in Living Kidney Donors
Agboli, I, Moore, LW, Nguyen, DTM, Graviss, EA, Ibrahim, H, Gaber, AO & Sadhu, A 2018, 2018 American Transplant Congress (ATC), Seattle, United States, 6/2/18 - 6/6/18, .

Transplantation for Hepatocellular carcinoma is there a tumor size limit?
Ahmed, D, Larry, T, Mark, GR, Edward, G, Sherif, M, Amany, S, Mostafa, E-S & Osama, GA 2018, Transplantation Proceedings. DOI: 10.1016/j.transproceed.2018.04.038

Liver transplantation for locally advanced intrahepatic cholangiocarcinoma treated with neoadjuvant therapy: a prospective case-series
Lunsford, KE, Javle, M, Heyne, K, Shroff, RT, Abdel-Wahab, R, Gupta, N, Mobley, CM, Saharia, A, Victor, DW, Nguyen, DT, Graviss, EA, Kaseb, AO, McFadden, RS, Aloia, TA, Conrad, C, Li, XC, Monsour, HP, Gaber, AO, Vauthey, J-N, Ghobrial, RM & Methodist–MD Anderson Joint Cholangiocarcinoma Collaborative Committee (MMAJCCC) 2018, The lancet. Gastroenterology & hepatology. DOI: 10.1016/S2468-1253(18)30045-1

Transplantation in value-based care for patients with renal failure
Gaber, O, Reed, A, Pruett, T & Emond, J 2018, American Journal of Transplantation. DOI: 10.1111/ajt.14878

Conversion from tacrolimus-mycophenolate mofetil to tacrolimus-mTOR immunosuppression after kidney-pancreas transplantation reduces the incidence of both BK and CMV viremia
Knight, RJ, Graviss, EA, Nguyen, DT, Kuten, SA, Patel, SJ, Gaber, L & Gaber, AO 2018, Clinical Transplantation, pp. e13265. DOI: 10.1111/ctr.13265

Unexplained fever after pancreas transplantation
Klasek, R, Kuten, SA, Patel, SJ, Graviss, EA, Nguyen, DT, Hobeika, MJ, Gaber, OA, Podder, H & Knight, RJ 2018, Clinical Transplantation, pp. e13351. DOI: 10.1111/ctr.13351

Treatment of Refractory Gastrointestinal Bleeding in Patients With Portal Hypertension: A Case Series and Treatment Algorithm
Balogh, J, Gordon-Burroughs, S, Schwarz, P, Galati, J, McFadden, RA, Cusick, M, Snyder, MJ, Bailey, HR, Weiner, M, Wong, A, Ochoa, RA, Saharia, A, Gaber, AO & Ghobrial, RM 2017, Transplantation proceedings, vol. 49, no. 8, pp. 1864-1869. DOI: 10.1016/j.transproceed.2017.06.022

Belatacept conversion in an HIV-positive kidney transplant recipient following anti-thymocyte globulin induction
Kuten, SA, Patel, SJ, Baru, A, Gaber, AO, Crutchley, RD, Ramanathan, V & Knight, RJ 2017, Transplant Infectious Disease, vol. 19, no. 5, e12748. DOI: 10.1111/tid.12748

Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism
Mukherjee, A, Morales-Scheihing, D, Salvadores, N, Moreno-Gonzalez, I, Gonzalez, C, Taylor-Presse, K, Mendez, N, Shahnawaz, M, Gaber, AO, Sabek, OM, Fraga, DW & Soto, C 2017, The Journal of experimental medicine. DOI: 10.1084/jem.20161134

Optimal cut points of plasma and urine neutrophil gelatinase-associated lipocalin for the prediction of acute kidney injury among critically ill adults: Retrospective determination and clinical validation of a prospective multicentre study
Tecson, KM, Erhardtsen, E, Eriksen, PM, Gaber, AO, Germain, M, Golestaneh, L, De Los Angeles Lavoria, M, Moore, LW & McCullough, PA 2017, BMJ Open, vol. 7, no. 7, e016028. DOI: 10.1136/bmjopen-2017-016028