Amy C. Schefler, MD, FACS

Associate Professor of Clinical Ophthalmology, Academic Institute
Associate Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Areas Of Expertise

Ocular oncology Retinablastoma Choroidal melanoma
Education & Training

Clinical Fellowship, Bascom Palmer Eye Inst & Hosp
Residency, Bascom Palmer Eye Inst & Hosp
Internship, LAC-Olive View/UCLA Medical Center
MD, Weill-Cornell Medical College
Publications

Randomized Trial of Monthly Versus As-Needed Intravitreal Ranibizumab for Radiation Retinopathy–Related Macular Edema: 1-Year Outcomes
RRR Study Group 2020, American Journal of Ophthalmology, vol. 216, pp. 165-173. https://doi.org/10.1016/j.ajo.2020.03.045

Global Retinoblastoma Presentation and Analysis by National Income Level
Fabian, ID, Abdallah, E, Abdullahi, SU, Abdulqader, RA, Adamou Boubacar, S, Ademola-Popoola, DS, Adio, A, Afshar, AR, Aggarwal, P, Aghaji, AE, Ahmad, A, Akib, MNR, Al Harby, L, Al Ani, MH, Alakbarova, A, Portabella, SA, Al-Badri, SAF, Alcasabas, APA, Al-Dahmash, SA, Alejos, A, Alemany-Rubio, E, Alfa Bio, AI, Alfonso Carreras, Y, Al-Haddad, C, Al-Hussaini, HHY, Ali, AM, Alia, DB, Al-Jadiry, MF, Al-Jumaly, U, Alkatan, HM, All-Eriksson, C, Al-Mafrachi, AARM, Almeida, AA, Alsawidi, KM, Al-Shaheen, AASM, Al-Shammary, EH, Amiruddin, PO, Antonino, R, Astbury, NJ, Atalay, HT, Atchaneeyasakul, LO, Atsiaya, R, Attaseth, T, Aung, TH, Ayala, S, Baizakova, B, Balaguer, J, Balayeva, R, Balwierz, W, Barranco, H, Bascaran, C, Beck Popovic, M, Benavides, R, Benmiloud, S, Bennani Guebessi, N, Berete, RC, Berry, JL, Bhaduri, A, Bhat, S, Biddulph, SJ, Biewald, EM, Bobrova, N, Boehme, M, Boldt, HC, Bonanomi, MTBC, Bornfeld, N, Bouda, GC, Bouguila, H, Boumedane, A, Brennan, RC, Brichard, BG, Buaboonnam, J, Calderón-Sotelo, P, Calle Jara, DA, Camuglia, JE, Cano, MR, Capra, M, Cassoux, N, Castela, G, Castillo, L, Català-Mora, J, Chantada, GL, Chaudhry, S, Chaugule, SS, Chauhan, A, Chawla, B, Chernodrinska, VS, Chiwanga, FS, Chuluunbat, T, Cieslik, K, Cockcroft, RL, Comsa, C, Correa, ZM, Correa Llano, MG, Corson, TW, Cowan-Lyn, KE, Csóka, M, Cui, X, Da Gama, IV, Dangboon, W, Das, A, Das, S, Davanzo, JM, Davidson, A, De Potter, P, Delgado, KQ, Demirci, H, Desjardins, L, Diaz Coronado, RY, Dimaras, H, Dodgshun, AJ, Donaldson, C, Donato Macedo, CR, Dragomir, MD, Du, Y, Du Bruyn, M, Edison, KS, Eka Sutyawan, IW, El Kettani, A, Elbahi, AM, Elder, JE, Elgalaly, D, Elhaddad, AM, Elhassan, MMA, Elzembely, MM, Essuman, VA, Evina, TGA, Fadoo, Z, Fandiño, AC, Faranoush, M, Fasina, O, Fernández, DDPG, Fernández-Teijeiro, A, Foster, A, Frenkel, S, Fu, LD, Fuentes-Alabi, SL, Gallie, BL, Gandiwa, M, Garcia, JL, García Aldana, D, Gassant, PY, Geel, JA, Ghassemi, F, Girón, AV, Gizachew, Z, Goenz, MA, Gold, AS, Goldberg-Lavid, M, Gole, GA, Gomel, N, Gonzalez, E, Gonzalez Perez, G, González-Rodríguez, L, Garcia Pacheco, HN, Graells, J, Green, L, Gregersen, PA, Grigorovski, NDAK, Guedenon, KM, Gunasekera, DS, Gündüz, AK, Gupta, H, Gupta, S, Hadjistilianou, T, Hamel, P, Hamid, SA, Hamzah, N, Hansen, ED, Harbour, JW, Hartnett, ME, Hasanreisoglu, M, Hassan, S, Hassan, S, Hederova, S, Hernandez, J, Hernandez, LMC, Hessissen, L, Hordofa, DF, Huang, LC, Hubbard, GB, Hummlen, M, Husakova, K, Hussein Al-Janabi, AN, Ida, R, Ilic, VR, Jairaj, V, Jeeva, I, Jenkinson, H, Ji, X, Jo, DH, Johnson, KP, Johnson, WJ, Jones, MM, Kabesha, TBA, Kabore, RL, Kaliki, S, Kalinaki, A, Kantar, M, Kao, LY, Kardava, T, Kebudi, R, Kepak, T, Keren-Froim, N, Khan, ZJ, Khaqan, HA, Khauv, P, Kheir, WJ, Khetan, V, Khodabande, A, Khotenashvili, Z, Kim, JW, Kim, JH, Kiratli, H, Kivelä, TT, Klett, A, Komba Palet, JEK, Krivaitiene, D, Kruger, M, Kulvichit, K, Kuntorini, MW, Kyara, A, Lachmann, ES, Lam, CPS, Lam, GC, Larson, SA, Latinovic, S, Laurenti, KD, Le, BHA, Lecuona, K, Leverant, AA, Li, C, Limbu, B, Long, QB, López, JP, Lukamba, RM, Lumbroso, L, Luna-Fineman, S, Lutfi, D, Lysytsia, L, Magrath, GN, Mahajan, A, Majeed, AR, Maka, E, Makan, M, Makimbetov, EK, Manda, C, Martín Begue, N, Mason, L, Mason, JO, Matende, IO, Materin, M, Mattosinho, CCDS, Matua, M, Mayet, I, Mbumba, FB, McKenzie, JD, Medina-Sanson, A, Mehrvar, A, Mengesha, AA, Menon, V, Mercado, GJVD, Mets, MB, Midena, E, Mishra, DKC, Mndeme, FG, Mohamedani, AA, Mohammad, MT, Moll, AC, Montero, MM, Morales, RA, Moreira, C, Mruthyunjaya, P, Msina, MS, Msukwa, G, Mudaliar, SS, Muma, KI, Munier, FL, Murgoi, G, Murray, TG, Musa, KO, Mushtaq, A, Mustak, H, Muyen, OM, Naidu, G, Nair, AG, Naumenko, L, Ndoye Roth, PA, Nency, YM, Neroev, V, Ngo, H, Nieves, RM, Nikitovic, M, Nkanga, ED, Nkumbe, H, Nuruddin, M, Nyaywa, M, Obono-Obiang, G, Oguego, NC, Olechowski, A, Oliver, SCN, Osei-Bonsu, P, Ossandon, D, Paez-Escamilla, MA, Pagarra, H, Painter, SL, Paintsil, V, Paiva, L, Pal, BP, Palanivelu, MS, Papyan, R, Parrozzani, R, Parulekar, M, Pascual Morales, CR, Paton, KE, Pawinska-Wasikowska, K, PeEr, J, Peña, A, Peric, S, Pham, CTM, Philbert, R, Plager, DA, Pochop, P, Polania, RA, Polyakov, VG, Pompe, MT, Pons, JJ, Prat, D, Prom, V, Purwanto, I, Qadir, AO, Qayyum, S, Qian, J, Rahman, A, Rahman, S, Rahmat, J, Rajkarnikar, P, Ramanjulu, R, Ramasubramanian, A, Ramirez-Ortiz, MA, Raobela, L, Rashid, R, Reddy, MA, Reich, E, Renner, LA, Reynders, D, Ribadu, D, Riheia, MM, Ritter-Sovinz, P, Rojanaporn, D, Romero, L, Roy, SR, Saab, RH, Saakyan, S, Sabhan, AH, Sagoo, MS, Said, AMA, Saiju, R, Salas, B, San Román Pacheco, S, Sánchez, GL, Sayalith, P, Scanlan, TA, Schefler, AC, Schoeman, J, Sedaghat, A, Seregard, S, Seth, R, Shah, AS, Shakoor, SA, Sharma, MK, Sherief, ST, Shetye, NG, Shields, CL, Siddiqui, SN, Sidi Cheikh, S, Silva, S, Singh, AD, Singh, N, Singh, U, Singha, P, Sitorus, RS, Skalet, AH, Soebagjo, HD, Sorochynska, T, Ssali, G, Stacey, AW, Staffieri, SE, Stahl, ED, Stathopoulos, C, Stirn Kranjc, B, Stones, DK, Strahlendorf, C, Suarez, MEC, Sultana, S, Sun, X, Sundy, M, Superstein, R, Supriyadi, E, Surukrattanaskul, S, Suzuki, S, Svojgr, K, Sylla, F, Tamamyan, G, Tan, D, Tandili, A, Tarrillo Leiva, FF, Tashvighi, M, Tateshi, B, Tehuteru, ES, Teixeira, LF, Teh, KH, Theophile, T, Toledano, H, Trang, DL, Traoré, F, Trichaiyaporn, S, Tuncer, S, Tyau-Tyau, H, Umar, AB, Unal, E, Uner, OE, Urbak, SF, Ushakova, TL, Usmanov, RH, Valeina, S, Van Hoefen Wijsard, M, Varadisai, A, Vasquez, L, Vaughan, LO, Veleva-Krasteva, NV, Verma, N, Victor, AA, Viksnins, M, Villacís Chafla, EG, Vishnevskia-Dai, V, Vora, T, Wachtel, AE, Wackernagel, W, Waddell, K, Wade, PD, Wali, AH, Wang, YZ, Weiss, A, Wilson, MW, Wime, ADC, Wiwatwongwana, A, Wiwatwongwana, D, Wolley Dod, C, Wongwai, P, Xiang, D, Xiao, Y, Yam, JC, Yang, H, Yanga, JM, Yaqub, MA, Yarovaya, VA, Yarovoy, AA, Ye, H, Yousef, YA, Yuliawati, P, Zapata López, AM, Zein, E, Zhang, C, Zhang, Y, Zhao, J, Zheng, X, Zhilyaeva, K, Zia, N, Ziko, OAO, Zondervan, M & Bowman, R 2020, JAMA oncology, vol. 6, no. 5, pp. 685-695. https://doi.org/10.1001/jamaoncol.2019.6716

Practice Patterns for the Treatment of Uveal Melanoma with Iodine-125 Plaque Brachytherapy: Ocular Oncology Study Consortium Report 5
Binder, C, Mruthyunjaya, P, Schefler, AC, Seider, MI, Crilly, R, Hung, A, Meltsner, S, Mowery, Y, Kirsch, DG, Teh, BS, Jennelle, RLS, Studenski, MT, Liu, W, Lee, C, Hayman, JA, Kastner, B, Hadsell, M & Skalet, AH 2020, Ocular Oncology and Pathology, vol. 6, no. 3, pp. 210-218. https://doi.org/10.1159/000504312

CORRELATION OF GENE EXPRESSION PROFILE STATUS AND AMERICAN JOINT COMMISSION ON CANCER STAGE IN UVEAL MELANOMA
Ocular Oncology Study Consortium 2020, Retina (Philadelphia, Pa.), vol. 40, no. 2, pp. 214-224. https://doi.org/10.1097/IAE.0000000000002385

Multi-center analysis of intraocular biopsy technique and outcomes for uveal melanoma: Ocular Oncology Study Consortium report 4
Ocular Oncology Study Consortium 2020, Graefes Archive for Clinical and Experimental Ophthalmology, vol. 258, no. 2, pp. 427-435. https://doi.org/10.1007/s00417-019-04531-8

Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy: Outcomes from the Randomized RECOVERY Trial
Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy Study Group 2019, Ophthalmology Retina, vol. 3, no. 12, pp. 1076-1086. https://doi.org/10.1016/j.oret.2019.07.011

RELATIONSHIP OF CLINICAL FEATURES AND BASELINE TUMOR SIZE WITH GENE EXPRESSION PROFILE STATUS IN UVEAL MELANOMA: A Multi-institutional Study
Ocular Oncology Study Consortium 2019, Retina (Philadelphia, Pa.), vol. 39, no. 6, pp. 1154-1164. https://doi.org/10.1097/IAE.0000000000002113

Randomized Trial of Treat and Extend Ranibizumab With and Without Navigated Laser Versus Monthly Dosing for Diabetic Macular Edema: TREX-DME 2-Year Outcomes
TREX-DME Study Group 2019, American Journal of Ophthalmology, vol. 202, pp. 91-99. https://doi.org/10.1016/j.ajo.2019.02.005

Relationship between clinical features, GEP class, and PRAME expression in uveal melanoma
Schefler, AC, Koca, E, Bernicker, EH & Correa, ZM 2019, Graefes Archive for Clinical and Experimental Ophthalmology. https://doi.org/10.1007/s00417-019-04335-w

Trends in Radiation Practices for Female Ocular Oncologists in North America: A Collaborative Study of the International Society of Ocular Oncology
Shah, SN, Kogachi, K, Correa, ZM, Schefler, AC, Aronow, ME, Callejo, SA, Cebulla, CM, Day-Ghafoori, S, Francis, JH, Lally, S, McCannel, TA, Paton, KE, Phan, IT, Pointdujour-Lim, R, Ramasubramanian, A, Rath, P, Shields, CL, Skalet, AH, Wells, JR, Jennelle, RL & Berry, JL 2019, Ocular Oncology and Pathology, vol. 5, no. 1, pp. 54-59. https://doi.org/10.1159/000489219

Intraocular Metastasis in Unilateral Multifocal Uveal Melanoma without Melanocytosis or Germline BAP1 Mutations
Durante, MA, Walter, SD, Paez-Escamilla, M, Tokarev, J, Decatur, CL, Dubovy, SR, Schefler, AC & Harbour, JW 2019, JAMA ophthalmology. https://doi.org/10.1001/jamaophthalmol.2019.3941

A rare presentation of choroidal metastasis from primary esophageal adenocarcinoma successfully treated with intensity-modulated radiation therapy
Date, RC, Adams, MK, Teh, BS, Schefler, AC, Musher, BL, Farach, AM & Weng, CY 2018, American Journal of Ophthalmology Case Reports, vol. 11, pp. 19-22. https://doi.org/10.1016/j.ajoc.2018.04.021

Biopsy of a choroidal melanoma using transvitreal pars plana vitrectomy
Tang, PH, Shields, RA, Mruthyunjaya, P & Schefler, AC 2018, Ophthalmic Surgery Lasers and Imaging Retina, vol. 49, no. 8, pp. 645-647. https://doi.org/10.3928/23258160-20180803-16

Use of femoral artery ultrasound during intraarterial chemotherapy for children under 10 kg with retinoblastoma
Kim, RS, Dannenbaum, MJ, Lin, MW, Bretana, ME, Brown, DL & Schefler, AC 2018, Retina, vol. 38, no. 7, pp. 1420-1426. https://doi.org/10.1097/IAE.0000000000001713

Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti–Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema
Diabetic Retinopathy Clinical Research Network 2018, Ophthalmology, vol. 125, no. 7, pp. 1054-1063. https://doi.org/10.1016/j.ophtha.2018.01.019

Laser/light applications in ophthalmology: Posterior segment applications
Villegas, VM, Murray, TG, Schefler, AC & Wykoff, CC 2018, . in Lasers in Dermatology and Medicine: Dental and Medical Applications. Springer International Publishing, pp. 17-32. https://doi.org/10.1007/978-3-319-76220-3_2

Yield, techniques, and complications of transvitreal and transscleral biopsies in small uveal melanoma
Kim, RS, Chévez-Barrios, P, Divatia, MK, Bretana, ME, Teh, BS & Schefler, AC 2018, JAMA ophthalmology, vol. 136, no. 5, pp. 482-488. https://doi.org/10.1001/jamaophthalmol.2018.0561

Comparison of monthly vs treat-and-extend regimens for individuals with macular edema who respond well to anti-vascular endothelial growth factor medications: Secondary outcomes from the SCORE2 randomized clinical trial
SCORE2 Investigator Group 2018, JAMA ophthalmology, vol. 136, no. 4, pp. 337-345. https://doi.org/10.1001/jamaophthalmol.2017.6843

Recent advancements in the management of retinoblastoma and uveal melanoma [version 1; referees: 2 approved]
Schefler, AC & Kim, RS 2018, F1000Research, vol. 7, 476. https://doi.org/10.12688/f1000research.11941.1

Elevated Choroidal Thickness and Central Serous Chorioretinopathy in the Fellow Eyes of Patients with Circumscribed Choroidal Hemangioma
Kim, RS, Jain, RR, Brown, DM, Bretana, ME, Kegley, EN, Singer, MA, Aragon, AV & Schefler, AC 2018, Ocular Oncology and Pathology, vol. 4, no. 6. https://doi.org/10.1159/000486864

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