Amy C. Schefler, MD, FACS

Associate Professor of Clinical Ophthalmology, Institute for Academic Medicine
Associate Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Areas Of Expertise

Ocular oncology Retinablastoma Choroidal melanoma
Education & Training

Clinical Fellowship, Bascom Palmer Eye Inst & Hosp
Residency, Bascom Palmer Eye Inst & Hosp
Internship, LAC-Olive View/UCLA Medical Center
MD, Weill-Cornell Medical College
Publications

Randomized Trial of Treat and Extend Ranibizumab With and Without Navigated Laser Versus Monthly Dosing for Diabetic Macular Edema: TREX-DME 2-Year Outcomes
TREX-DME Study Group 2019, American Journal of Ophthalmology, vol. 202, pp. 91-99. https://doi.org/10.1016/j.ajo.2019.02.005

Trends in Radiation Practices for Female Ocular Oncologists in North America: A Collaborative Study of the International Society of Ocular Oncology
Shah, SN, Kogachi, K, Correa, ZM, Schefler, AC, Aronow, ME, Callejo, SA, Cebulla, CM, Day-Ghafoori, S, Francis, JH, Lally, S, McCannel, TA, Paton, KE, Phan, IT, Pointdujour-Lim, R, Ramasubramanian, A, Rath, P, Shields, CL, Skalet, AH, Wells, JR, Jennelle, RL & Berry, JL 2019, Ocular Oncology and Pathology, vol. 5, no. 1, pp. 54-59. https://doi.org/10.1159/000489219

Relationship between clinical features, GEP class, and PRAME expression in uveal melanoma
Schefler, AC, Koca, E, Bernicker, EH & Correa, ZM 2019, Graefes Archive for Clinical and Experimental Ophthalmology. https://doi.org/10.1007/s00417-019-04335-w

Intraocular Metastasis in Unilateral Multifocal Uveal Melanoma without Melanocytosis or Germline BAP1 Mutations
Durante, MA, Walter, SD, Paez-Escamilla, M, Tokarev, J, Decatur, CL, Dubovy, SR, Schefler, AC & Harbour, JW 2019, JAMA ophthalmology. https://doi.org/10.1001/jamaophthalmol.2019.3941

A rare presentation of choroidal metastasis from primary esophageal adenocarcinoma successfully treated with intensity-modulated radiation therapy
Date, RC, Adams, MK, Teh, BS, Schefler, AC, Musher, BL, Farach, AM & Weng, CY 2018, American journal of ophthalmology case reports, vol. 11, pp. 19-22. https://doi.org/10.1016/j.ajoc.2018.04.021

Biopsy of a choroidal melanoma using transvitreal pars plana vitrectomy
Tang, PH, Shields, RA, Mruthyunjaya, P & Schefler, AC 2018, Ophthalmic Surgery Lasers and Imaging Retina, vol. 49, no. 8, pp. 645-647. https://doi.org/10.3928/23258160-20180803-16

Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial
TREX-AMD Study Group 2018, American Journal of Ophthalmology, vol. 192, pp. 84-90. https://doi.org/10.1016/j.ajo.2018.05.008

Yield, techniques, and complications of transvitreal and transscleral biopsies in small uveal melanoma
Kim, RS, Chévez-Barrios, P, Divatia, MK, Bretana, ME, Teh, BS & Schefler, AC 2018, JAMA Ophthalmology, vol. 136, no. 5, pp. 482-488. https://doi.org/10.1001/jamaophthalmol.2018.0561

Comparison of monthly vs treat-and-extend regimens for individuals with macular edema who respond well to anti-vascular endothelial growth factor medications: Secondary outcomes from the SCORE2 randomized clinical trial
SCORE2 Investigator Group 2018, JAMA Ophthalmology, vol. 136, no. 4, pp. 337-345. https://doi.org/10.1001/jamaophthalmol.2017.6843

RELATIONSHIP OF CLINICAL FEATURES AND BASELINE TUMOR SIZE WITH GENE EXPRESSION PROFILE STATUS IN UVEAL MELANOMA: A Multi-institutional Study
Ocular Oncology Study Consortium 2019, Retina (Philadelphia, Pa.), vol. 39, no. 6, pp. 1154-1164. https://doi.org/10.1097/IAE.0000000000002113

Recent advancements in the management of retinoblastoma and uveal melanoma [version 1; referees: 2 approved]
Schefler, AC & Kim, RS 2018, F1000Research, vol. 7, 476. https://doi.org/10.12688/f1000research.11941.1

Elevated Choroidal Thickness and Central Serous Chorioretinopathy in the Fellow Eyes of Patients with Circumscribed Choroidal Hemangioma
Kim, RS, Jain, RR, Brown, DM, Bretana, ME, Kegley, EN, Singer, MA, Aragon, AV & Schefler, AC 2018, Ocular Oncology and Pathology, vol. 4, no. 6. https://doi.org/10.1159/000486864

Risk of extraocular extension in eyes with retinoblastoma receiving intravitreous chemotherapy
Francis, JH, Abramson, DH, Ji, X, Shields, CL, Teixeira, LF, Schefler, AC, Cassoux, N, Hadjistilianou, D, Berry, JL, Frenkel, S & Munier, FL 2017, JAMA Ophthalmology, vol. 135, no. 12, pp. 1426-1429. https://doi.org/10.1001/jamaophthalmol.2017.4600

Association between traditional clinical high-risk features and gene expression profile classification in uveal melanoma
Nguyen, BT, Kim, RS, Bretana, ME, Kegley, E & Schefler, AC 2017, Graefes Archive for Clinical and Experimental Ophthalmology, pp. 1-7. https://doi.org/10.1007/s00417-017-3856-x

USE OF FEMORAL ARTERY ULTRASOUND DURING INTRAARTERIAL CHEMOTHERAPY FOR CHILDREN UNDER 10 KG WITH RETINOBLASTOMA
Kim, RS, Dannenbaum, MJ, Lin, MW, Bretana, ME, Brown, DL & Schefler, AC 2017, Retina. https://doi.org/10.1097/IAE.0000000000001713

Histopathologic Analysis of Transvitreal Fine Needle Aspiration Biopsy Needle Tracts for Uveal Melanoma
Kim, RS, Chevez-Barrios, P, Bretana, ME, Wong, TP, Teh, BS & Schefler, AC 2017, American Journal of Ophthalmology, vol. 174, pp. 9-16. https://doi.org/10.1016/j.ajo.2016.10.019

Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial
Abdelfattah, NS, Al-Sheikh, M, Pitetta, S, Mousa, A, Sadda, SVR, Wykoff, CC, Wykoff, CC, Croft, DE, Brown, DM, Wang, R, Payne, JF, Clark, L, Abdelfattah, NS, Sadda, SVR, Chen, E, Fish, RH, Fish, RH, Kim, RY, Major, JC, Major, JC, Schefler, AC, Shah, AR, Shah, AR, Vance, SK, Wong, TP & Wong, TP 2017, Ophthalmology, vol. 124, no. 2, pp. 215-223. https://doi.org/10.1016/j.ophtha.2016.10.002

Early outcomes of uveal melanoma treated with intraoperative ultrasound guided brachytherapy using custom built plaques
Tann, AW, Teh, BS, Scarboro, SB, Lewis, GD, Bretana, ME, Croft, PC, Raizen, Y, Butler, EB, Kim, RS, Chevez-Barrios, P & Schefler, AC 2017, Practical radiation oncology. https://doi.org/10.1016/j.prro.2017.01.002

Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma
Mruthyunjaya, P, Seider, MI, Stinnett, S & Schefler, AC 2016, Ophthalmology. https://doi.org/10.1016/j.ophtha.2017.04.013

Intraarterial chemotherapy for retinoblastoma: History, technique, and update on outcomes
Kim, RS, Dannenbaum, MJ & Schefler, AC 2016, Retina Today, vol. 2016July-August, pp. 65-70.

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