Reginald F. Munden, MD, DMD, MBA

Professor of Radiology, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Dr. Munden earned his D.M.D. in 1982 and his M.D. in 1990 from the Medical University of South Carolina in Charleston. After dental school, he was in private practice for 3 years and served as an assistant professor of dentistry at the Medical University of South Carolina Dental School for 3 years. After medical school, he remained in Charleston for his residency in Diagnostic Radiology. In 1994, Dr. Munden moved to Boston where he completed a Fellowship in Thoracic Radiology. His first radiology academic position was as an Assistant Professor of Radiology at the University of Texas Medical School in Houston. In 1997, Dr. Munden took a position at the University of Texas MD Anderson Cancer Center where he spent the next 11 years, obtaining tenure as Professor of Radiology in 2006. In 2008, he was recruited to the University of Alabama in Birmingham to become the Chair of Radiology. He held the Witten-Stanley Endowed Chair of Radiology position for 2 years. In 2010, he was recruited back to MD Anderson to lead the lung cancer screening program. He joined the Houston Methodist Hospital in 2013.

Dr. Munden is a member of and serves in leadership positions in a number of national and international radiology organizations, including the World Congress of Thoracic Imaging, Society of Thoracic Radiology, Radiological Society of North America (RSNA), American Roentgen Ray Society, American College of Radiology (ACR), American College of Radiology Imaging Network (ACRIN), and the Radiation Therapy Oncology Group. Currently, he serves as Chair of Chest Scientific Committee of the RSNA, and is a member of the ACRIN Executive Committee of the National Lung Screening Trial and the ACR Practice Guidelines for CT Screening of Lung Cancer.


Description of Research

Dr. Munden has been extensively involved in evaluating the role of imaging (including chest radiographs, CT, and PET/CT) in lung cancer and other thoracic malignancies. He has extensive experience in the application and translation of imaging research for evaluating lung cancer, esophageal cancer, and other thoracic malignancies. He has a special interest in assessing the tumor response to therapy and lung cancer screening. He has participated in over 40 clinical trials and served as the National Lung Screening Trial (NLST) site PI for the MD Anderson Cancer Center (MDACC). This site participated in targeted recruitment of underrepresented populations for the NLST and has significant experience in recruitment for lung cancer screening. His interest in screening continues with further evaluation and publication of NLST data, development of recommendations and guidelines for lung cancer screening, and biomarker utilization for screening and assessing the value of lung cancer screening.

Areas Of Expertise

Lung cancer Esophageal cancer Thoracic imaging
Education & Training

, Auburn University

A brief measure of Smokers' knowledge of lung cancer screening with low-dose computed tomography
Lowenstein, LM, Richards, VF, Leal, VB, Housten, AJ, Bevers, TB, Cantor, SB, Cinciripini, PM, Cofta-Woerpel, LM, Escoto, KH, Godoy, MCB, Linder, SK, Munden, RF & Volk, RJ 2016, Preventive Medicine Reports, vol 4, pp. 351-356. DOI:

Managing Incidental Lung Nodules in Patients With a History of Oncologic Disease: A Survey of Thoracic Radiologists
Occhipinti, M, Heidinger, BH, Pfannenberg, C, Munden, RF, Eisenberg, RL & Bankier, AA 2016, Journal of Thoracic Imaging. DOI:

Improved identification of sternal injuries with multidetector computed tomography (MDCT): Sagittal reconstructions
Terry, NLJ, Watts, JR, Sonavane, SK, Beasley, TM, Munden, R, Nath, PH & Singh, SP 2016, Clinical Imaging, vol 40, no. 4, pp. 739-744. DOI:

Normative reference values of thoracic aortic diameter in American College of Radiology Imaging Network (ACRIN 6654) arm of National Lung Screening Trial
McComb, BL, Munden, RF, Duan, F, Jain, AA, Tuite, C & Chiles, C 2016, Clinical Imaging, vol 40, no. 5, pp. 936-943. DOI:

Reply to "improved postoperative mortality rates after thoracic surgery for lung cancer" [CLM-D-16-00,187]
Munden, RF & Ginsberg, MS 2016, Clinical Imaging. DOI:

Postoperative complications after thoracic surgery for lung cancer
Rotman, JA, Plodkowski, AJ, Hayes, SA, de Groot, PM, Shepard, JAO, Munden, RF & Ginsberg, MS 2015, Clinical Imaging, vol 39, no. 5, pp. 735-749. DOI:

Association of coronary artery calcification and mortality in the national lung screening trial: A comparison of three scoring methods
Chiles, C, Duan, F, Gladish, GW, Ravenel, JG, Baginski, SG, Snyder, BS, DeMello, S, Desjardins, SS & Munden, RF 2015, Radiology, vol 276, no. 1, pp. 82-90. DOI:

Performance of lung-RADS in the national lung screening trial: A retrospective assessment
Pinsky, PF, Gierada, DS, Black, W, Munden, R, Nath, H, Aberle, D & Kazerooni, E 2015, Annals of Internal Medicine, vol 162, no. 7, pp. 485-491. DOI:

Lung cancer screening: How to do it
Carter, BW, de Groot, PM, Godoy, MCB & Munden, RF 2015, Seminars in Roentgenology, vol 50, no. 2, pp. 82-87. DOI:

Lung cancer screening - Why do it? Tobacco, the history of screening, and future challenges
de Groot, PM, Carter, BW, Godoy, MCB & Munden, RF 2015, Seminars in Roentgenology, vol 50, no. 2, pp. 72-81. DOI:

Radiographic evaluation of the pleural fluid accumulation rate after pneumonectomy
Munden, RF, OSullivan, PJ, Liu, P & Vaporciyan, AA 2015, Clinical Imaging, vol 39, no. 2, pp. 247-250. DOI:

Marketing and branding for a radiologist
Munden, RF 2015, Journal of the American College of Radiology, vol 12, no. 2, pp. 130-131. DOI:

Early detection of lung cancer: Do we have any markers?
El-Zein, RA & Munden, RF 2015, 2nd Annual Houston Methodidst Cancer Symposium, Houston, United States, 6/19/15, .

Cost-effectiveness of CT screening in the National Lung Screening Trial
Black, WC, Gareen, IF, Soneji, SS, Sicks, JD, Keeler, EB, Aberle, DR, Naeim, A, Church, TR, Silvestri, GA, Gorelick, J, Gatsonis, C, National Lung Screening Trial Research Team & Munden, RF 2014, The New England journal of medicine, vol 371, no. 19, pp. 1793-802. DOI:

Opportunities for nanotheranosis in lung cancer and pulmonary metastasis
Key, J, Kim, YS, Tatulli, F, Palange, AL, O’Neill, B, Aryal, S, Ramirez, M, Liu, X, Ferrari, M, Munden, R & Decuzzi, P 2014, Clinical and Translational Imaging, vol 2, no. 5, pp. 427-437. DOI:

Computed tomography screening for lung cancer: a survey of society of thoracic radiology members
Eberth, JM, Qiu, R, Linder, SK, Gallant, NR & Munden, RF 2014, Journal of thoracic imaging, vol 29, no. 5, pp. 289-292. DOI:

ACR-STR practice parameter for the performance and reporting of lung cancer screening thoracic computed tomography (CT): 2014 (Resolution 4)
Kazerooni, EA, Austin, JHM, Black, WC, Dyer, DS, Hazelton, TR, Leung, AN, McNitt-Gray, MF, Munden, RF & Pipavath, S 2014, Journal of thoracic imaging, vol 29, no. 5, pp. 310-316. DOI:

Radiology and Lung Cancer Screening
De Groot, P & Munden, RF 2014, . in Lung Cancer: Fourth Edition. vol. 9781118468746, Wiley-Blackwell, pp. 176-190. DOI:

Feasibility of a patient decision aid about lung cancer screening with low-dose computed tomography
Volk, RJ, Linder, SK, Leal, VB, Rabius, V, Cinciripini, PM, Kamath, GR, Munden, RF & Bevers, TB 2014, Preventive Medicine, vol 62, pp. 60-63. DOI:

Overdiagnosis in low-dose computed tomography screening for lung cancer
Patz, EF, Pinsky, P, Gatsonis, C, Sicks, JD, Kramer, BS, Tammemägi, MC, Chiles, C, Black, WC, Aberle, DR, NLST Overdiagnosis Manuscript Writing Team & Munden, RF 2014, JAMA Internal Medicine, vol 174, no. 2, pp. 269-74. DOI: