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Omonike Olaleye, PhD

Assistant Affiliate Member, Research Institute
Houston Methodist


Publications

Characterization of 2-hydroxy-1-naphthaldehyde isonicotinoyl hydrazone as a novel inhibitor of methionine aminopeptidases from Mycobacterium tuberculosis
John, SF, Aniemeke, E, Ha, NP, Chong, CR, Gu, P, Zhou, J, Zhang, Y, Graviss, EA, Liu, JO & Olaleye, OA 2016, Tuberculosis, vol 101, pp. S73-S77. DOI:

In vitro model of mycobacteria and HIV-1 co-infection for drug discovery
Vijayakumar, S, John, SF, Nusbaum, RJ, Ferguson, MR, Cirillo, JD, Olaleye, O & Endsley, JJ 2013, Tuberculosis, vol 93, no. SUPPL.. DOI:

Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl) methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases
Bhat, S, Olaleye, O, Meyer, KJ, Shi, W, Zhang, Y & Liu, JO 2012, Bioorganic and Medicinal Chemistry, vol 20, no. 14, pp. 4507-4513. DOI:

Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis
Olaleye, O, Raghunand, TR, Bhat, S, Chong, C, Gu, P, Zhou, J, Zhang, Y, Bishai, WR & Liu, JO 2011, Tuberculosis, vol 91, no. SUPPL. 1. DOI:

Methionine Aminopeptidases from Mycobacterium tuberculosis as Novel Antimycobacterial Targets
Olaleye, O, Raghunand, TR, Bhat, S, He, J, Tyagi, S, Lamichhane, G, Gu, P, Zhou, J, Zhang, Y, Grosset, J, Bishai, WR & Liu, JO 2010, Chemistry and Biology, vol 17, no. 1, pp. 86-97. DOI:

Targeting the role of N-terminal methionine processing enzymes in Mycobacterium tuberculosis
Olaleye, OA, Bishai, WR & Liu, JO 2009, Tuberculosis, vol 89, no. SUPPL.1. DOI:

Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome
Addlagatta, A, Quillin, ML, Omotoso, O, Liu, JO & Matthews, BW 2005, Biochemistry, vol 44, no. 19, pp. 7166-7174. DOI: