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Jin Wang, PhD

Professor of Transplant Immunology in Surgery, Institute for Academic Medicine
Full Member, Research Institute
Houston Methodist
Weill Cornell Medical College


jinwang@houstonmethodist.org
Biography

We are interested in understanding the mechanisms for long-term immune memory against infections. We have found that autophagy plays a critical role in the maintenance of memory B cells against virus infection. We aim to test novel strategies to boost the efficacy of vaccination by promoting autophagy in memory T cells and memory B cells. We will define the molecular pathways that regulate autophagy in pathogen-specific immune memory cells, and how deficiency in autophagy leads to defective mitochondrion accumulation, increased oxidative stress and cell death in these cells. In the long term, we aim to use the knowledge gained from this study to improve the efficacy of vaccination against infections and cancer in humans.

We have observed that Nix, a Bcl-2 family member, regulates selective mitochondrial autophagy. We are studying how Nix and its homolog, Bnip3, protect the maintenance of memory B cells through mitochondrial autophagy. We are also using proteomics and knockout approaches to determine how Nix and Bnip3 direct the selectivity in mitochondrial autophagy. This will help to reveal the mechanisms for selective autophagy in mitochondrial quality control for the promotion of immune memory, as well as protection against cancer and neurodegenerative diseases.  

Areas Of Expertise

Immunological memory Mitochondrial autophagy
Education & Training

Postdoctoral Associate , NIH
PhD , University of Southern California
Publications

Challenges and strategies for the eradication of the HIV reservoir
Kimata, JT, Rice, AP & Wang, J 2016, Current Opinion in Immunology, vol 42, pp. 65-70. DOI: 10.1016/j.coi.2016.05.015

Requirement for autophagy in the long-term persistence but not initial formation of memory B cells
Chen, M, Kodali, S, Jang, A, Kuai, L & Wang, J 2015, Journal of Immunology, vol 194, no. 6, pp. 2607-15. DOI: 10.4049/jimmunol.1403001

Role of Nix in the Maturation of Erythroid Cells through Mitochondrial Autophagy
Sun, H, Wang, L, Wang, J & Chen, M 2014, . in Mitophagy. vol. 4, Elsevier, pp. 127-137. DOI: 10.1016/B978-0-12-405528-5.00007-9

Essential role for autophagy in the maintenance of immunological memory against influenza infection.
Chen, M, Hong, MJ, Sun, H, Wang, L, Shi, X, Gilbert, BE, Corry, DB, Kheradmand, F & Wang, J 2014, Nature Medicine, vol 20, no. 5, pp. 503-510. DOI: 10.1038/nm.3521

Analyses of programmed cell death in dendritic cells
Chen, M, Huang, L & Wang, J 2013, Methods in molecular biology (Clifton, N.J.), vol 979, pp. 51-63. DOI: 10.1007/978-1-62703-290-2_6

Cleavage of anti-apoptotic Bcl-2 family members after TCR stimulation contributes to the decision between T cell activation and apoptosis
Guerrero, AD, Welschhans, RL, Chen, M & Wang, J 2013, Journal of Immunology, vol 190, no. 1, pp. 168-73. DOI: 10.4049/jimmunol.1201610

Promotion of Caspase Activation by Caspase-9-mediated Feedback Amplification of Mitochondrial Damage
Guerrero, AD, Schmitz, I, Chen, M & Wang, J 2012, Journal of clinical & cellular immunology, vol 3, no. 3. DOI: 10.4172/2155-9899.1000126

Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, DJ, Abdalla, FC, Abeliovich, H, Abraham, RT, Acevedo-Arozena, A, Adeli, K, Agholme, L, Agnello, M, Agostinis, P, Aguirre-Ghiso, JA, Ahn, HJ, Ait-Mohamed, O, Ait-Si-Ali, S, Akematsu, T, Akira, S, Al-Younes, HM, Al-Zeer, MA, Albert, ML, Albin, RL, Alegre-Abarrategui, J, Aleo, MF, Alirezaei, M, Almasan, A, Almonte-Becerril, M, Amano, A, Amaravadi, R, Amarnath, S, Amer, AO, Andrieu-Abadie, N, Anantharam, V, Ann, DK, Anoopkumar-Dukie, S, Aoki, H, Apostolova, N, Arancia, G, Aris, JP, Asanuma, K, Asare, NYO, Ashida, H, Askanas, V, Askew, DS, Auberger, P, Baba, M, Backues, SK, Baehrecke, EH, Bahr, BA, Bai, XY, Bailly, Y, Baiocchi, R, Baldini, G, Balduini, W, Ballabio, A, Bamber, BA, Bampton, ETW, Bánhegyi, G, Bartholomew, CR, Bassham, DC, Bast, RC, Batoko, H, Bay, BH, Beau, I, Béchet, DM, Begley, TJ, Behl, C, Behrends, C, Bekri, S, Bellaire, B, Bendall, LJ, Benetti, L, Berliocchi, L, Bernardi, H, Bernassola, F, Besteiro, S, Bhatia-Kissova, I, Bi, X, Biard-Piechaczyk, M, Blum, JS, Boise, LH, Bonaldo, P, Boone, DL, Bornhauser, BC, Bortoluci, KR, Bossis, I, Bost, F, Bourquin, JP, Boya, P, Boyer-Guittaut, M, Bozhkov, PV, Brady, NR, Brancolini, C, Brech, A, Brenman, JE, Brennand, A, Bresnick, EH, Brest, P, Bridges, D, Bristol, ML, Brookes, PS, Brown, EJ, Brumell, JH, Brunetti-Pierri, N, Brunk, UT, Bulman, DE, Bultman, SJ, Bultynck, G, Burbulla, LF, Bursch, W, Butchar, JP, Buzgariu, W, Bydlowski, SP, Cadwell, K, Cahová, M, Cai, D, Cai, J, Cai, Q, Calabretta, B, Calvo-Garrido, J, Camougrand, N, Campanella, M, Campos-Salinas, J, Candi, E, Cao, L, Caplan, AB, Carding, SR, Cardoso, SM, Carew, JS, Carlin, CR, Carmignac, V, Carneiro, LAM, Carra, S, Caruso, RA, Casari, G, Casas, C, Castino, R, Cebollero, E, Cecconi, F, Celli, J, Chaachouay, H, Chae, HJ, Chai, CY, Chan, DC, Chan, EY, Chang, RCC, Che, CM, Chen, CC, Chen, GC, Chen, GQ, Chen, M, Chen, Q, Chen, SSL, Chen, W, Chen, X, Chen, X, Chen, X, Chen, YG, Chen, Y, Chen, Y, Chen, YJ, Chen, Z, Cheng, A, Cheng, CHK, Cheng, Y, Cheong, H, Cheong, JH, Cherry, S, Chess-Williams, R, Cheung, ZH, Chevet, E, Chiang, HL, Chiarelli, R, Chiba, T, Chin, LS, Chiou, SH, Chisari, FV, Cho, CH, Cho, DH, Choi, AMK, Choi, D, Choi, KS, Choi, ME, Chouaib, S, Choubey, D, Choubey, V, Chu, CT, Chuang, TH, Chueh, SH, Chun, T, Chwae, YJ, Chye, ML, Ciarcia, R, Ciriolo, MR, Clague, MJ, Clark, RSB, Clarke, PGH, Clarke, R, Codogno, P, Coller, HA, Colombo, MI, Comincini, S, Condello, M, Condorelli, F, Cookson, MR, Coombs, GH, Coppens, I, Corbalan, R, Cossart, P, Costelli, P, Costes, S, Coto-Montes, A, Couve, E, Coxon, FP, Cregg, JM, Crespo, JL, Cronjé, MJ, Cuervo, AM, Cullen, JJ, Czaja, MJ, DAmelio, M, Darfeuille-Michaud, A, Davids, LM, Davies, FE, De Felici, M, De Groot, JF, De Haan, CAM, De Martino, L, De Milito, A, De Tata, V, Debnath, J, Degterev, A, Dehay, B, Delbridge, LMD, Demarchi, F, Deng, YZ, Dengjel, J, Dent, P, Denton, D, Deretic, V, Desai, SD, Devenish, RJ, Di Gioacchino, M, Di Paolo, G, Di Pietro, C, Díaz-Araya, G, Díaz-Laviada, I, Diaz-Meco, MT, Diaz-Nido, J, Dikic, I, Dinesh-Kumar, SP, Ding, WX, Distelhorst, CW, Diwan, A, Djavaheri-Mergny, M, Dokudovskaya, S, Dong, Z, Dorsey, FC, Dosenko, V, Dowling, JJ, Doxsey, S, Dreux, M, Drew, ME, Duan, Q, Duchosal, MA, Duff, K, Dugail, I, Durbeej, M, Duszenko, M, Edelstein, CL, Edinger, AL, Egea, G, Eichinger, L, Eissa, NT, Ekmekcioglu, S, El-Deiry, WS, Elazar, Z, Elgendy, M, Ellerby, LM, Er Eng, K, Engelbrecht, AM, Engelender, S, Erenpreisa, J, Escalante, R, Esclatine, A, Eskelinen, EL, Espert, L, Espina, V, Fan, H, Fan, J, Fan, QW, Fan, Z, Fang, S, Fang, Y, Fanto, M, Fanzani, A, Farkas, T, Farré, JC, Faure, M, Fechheimer, M, Feng, CG, Feng, J, Feng, Q, Feng, Y, Fésüs, L, Feuer, R, Figueiredo-Pereira, ME, Fimia, GM, Fingar, DC, Finkbeiner, S, Finkel, T, Finley, KD, Fiorito, F, Fisher, EA, Fisher, PB, Flajolet, M, Florez-McClure, ML, Florio, S, Fon, EA, Fornai, F, Fortunato, F, Fotedar, R, Fowler, DH, Fox, HS, Franco, R, Frankel, LB, Fransen, M, Fuentes, JM, Fueyo, J, Fujii, J, Fujisaki, K, Fujita, E, Fukuda, M, Furukawa, RH, Gaestel, M, Gailly, P, Gajewska, M, Galliot, B, Galy, V, Ganesh, S, Ganetzky, B, Ganley, IG, Gao, FB, Gao, GF, Gao, J, Garcia, L, Garcia-Manero, G, Garcia-Marcos, M, Garmyn, M, Gartel, AL, Gatti, E, Gautel, M, Gawriluk, TR, Gegg, ME, Geng, J, Germain, M, Gestwicki, JE, Gewirtz, DA, Ghavami, S, Ghosh, P, Giammarioli, AM, Giatromanolaki, AN, Gibson, SB, Gilkerson, RW, Ginger, ML, Ginsberg, HN, Golab, J, Goligorsky, MS, Golstein, P, Gomez-Manzano, C, Goncu, E, Gongora, C, Gonzalez, CD, Gonzalez, R, González-Estévez, C, González-Polo, RA, Gonzalez-Rey, E, Gorbunov, NV, Gorski, S, Goruppi, S, Gottlieb, RA, Gozuacik, D, Granato, GE, Grant, GD, Green, KN, Gregorc, A, Gros, F, Grose, C, Grunt, TW, Gual, P, Guan, JL, Guan, KL, Guichard, SM, Gukovskaya, AS, Gukovsky, I, Gunst, J, Gustafsson, AB, Halayko, AJ, Hale, AN, Halonen, SK, Hamasaki, M, Han, F, Han, T, Hancock, MK, Hansen, M, Harada, H, Harada, M, Hardt, SE, Harper, JW, Harris, AL, Harris, J, Harris, SD, Hashimoto, M, Haspel, JA, Hayashi, SI, Hazelhurst, LA, He, C, He, YW, Hébert, MJ, Heidenreich, KA, Helfrich, MH, Helgason, GV, Henske, EP, Herman, B, Herman, PK, Hetz, C, Hilfiker, S, Hill, JA, Hocking, LJ, Hofman, P, Hofmann, TG, Höhfeld, J, Holyoake, TL, Hong, MH, Hood, DA, Hotamisligil, GS, Houwerzijl, EJ, Høyer-Hansen, M, Hu, B, Hu, CAA, Hu, HM, Hua, Y, Huang, C, Huang, J, Huang, S, Huang, WP, Huber, TB, Huh, WK, Hung, TH, Hupp, TR, Hur, GM, Hurley, JB, Hussain, SNA, Hussey, PJ, Hwang, JJ, Hwang, S, Ichihara, A, Ilkhanizadeh, S, Inoki, K, Into, T, Iovane, V, Iovanna, JL, Ip, NY, Isaka, Y, Ishida, H, Isidoro, C, Isobe, KI, Iwasaki, A, Izquierdo, M, Izumi, Y, Jaakkola, PM, Jäättelä, M, Jackson, GR, Jackson, WT, Janji, B, Jendrach, M, Jeon, JH, Jeung, EB, Jiang, H, Jiang, H, Jiang, JX, Jiang, M, Jiang, Q, Jiang, X, Jiménez, A, Jin, M, Jin, S, Joe, CO, Johansen, T, Johnson, DE, Johnson, GVW, Jones, NL, Joseph, B, Joseph, SK, Joubert, AM, Juhász, G, Juillerat-Jeanneret, L, Jung, CH, Jung, YK, Kaarniranta, K, Kaasik, A, Kabuta, T, Kadowaki, M, Kagedal, K, Kamada, Y, Kaminskyy, VO, Kampinga, HH, Kanamori, H, Kang, C, Kang, KB, Il Kang, K, Kang, R, Kang, YA, Kanki, T, Kanneganti, TD, Kanno, H, Kanthasamy, AG, Kanthasamy, A, Karantza, V, Kaushal, GP, Kaushik, S, Kawazoe, Y, Ke, PY, Kehrl, JH, Kelekar, A, Kerkhoff, C, Kessel, DH, Khalil, H, Kiel, JAKW, Kiger, AA, Kihara, A, Kim, DR, Kim, DH, Kim, DH, Kim, EK, Kim, HR, Kim, JS, Kim, JH, Kim, JC, Kim, JK, Kim, PK, Kim, SW, Kim, YS, Kim, Y, Kimchi, A, Kimmelman, AC, King, JS, Kinsella, TJ, Kirkin, V, Kirshenbaum, LA, Kitamoto, K, Kitazato, K, Klein, L, Klimecki, WT, Klucken, J, Knecht, E, Ko, BCB, Koch, JC, Koga, H, Koh, JY, Koh, YH, Koike, M, Komatsu, M, Kominami, E, Kong, HJ, Kong, WJ, Korolchuk, VI, Kotake, Y, Koukourakis, MI, Kouri Flores, JB, Kovács, AL, Kraft, C, Krainc, D, Krämer, H, Kretz-Remy, C, Krichevsky, AM, Kroemer, G, Krüger, R, Krut, O, Ktistakis, NT, Kuan, CY, Kucharczyk, R, Kumar, A, Kumar, R, Kumar, S, Kundu, M, Kung, HJ, Kurz, T, Kwon, HJ, La Spada, AR, Lafont, F, Lamark, T, Landry, J, Lane, JD, Lapaquette, P, Laporte, JF, László, L, Lavandero, S, Lavoie, JN, Layfield, R, Lazo, PA, Le, W, Le Cam, L, Ledbetter, DJ, Lee, AJX, Lee, BW, Lee, GM, Lee, J, Lee, JH, Lee, M, Lee, MS, Lee, SH, Leeuwenburgh, C, Legembre, P, Legouis, R, Lehmann, M, Lei, HY, Lei, QY, Leib, DA, Leiro, J, Lemasters, JJ, Lemoine, A, Lesniak, MS, Lev, D, Levenson, VV, Levine, B, Levy, E, Li, F, Li, JL, Li, L, Li, S, Li, W, Li, XJ, Li, YB, Li, YP, Liang, C, Liang, Q, Liao, YF, Liberski, PP, Lieberman, A, Lim, HJ, Lim, KL, Lim, K, Lin, CF, Lin, FC, Lin, J, Lin, JD, Lin, K, Lin, WW, Lin, WC, Lin, YL, Linden, R, Lingor, P, Lippincott-Schwartz, J, Lisanti, MP, Liton, PB, Liu, B, Liu, CF, Liu, K, Liu, L, Liu, QA, Liu, W, Liu, YC, Liu, Y, Lockshin, RA, Lok, CN, Lonial, S, Loos, B, Lopez-Berestein, G, López-Otín, C, Lossi, L, Lotze, MT, Lõw, P, Lu, B, Lu, B, Lu, B, Lu, Z, Luciano, F, Lukacs, NW, Lund, AH, Lynch-Day, MA, Ma, Y, Macian, F, MacKeigan, JP, Macleod, KF, Madeo, F, Maiuri, L, Maiuri, MC, Malagoli, D, Malicdan, MCV, Malorni, W, Man, N, Mandelkow, EM, Manon, S, Manov, I, Mao, K, Mao, X, Mao, Z, Marambaud, P, Marazziti, D, Marcel, YL, Marchbank, K, Marchetti, P, Marciniak, SJ, Marcondes, M, Mardi, M, Marfe, G, Mariño, G, Markaki, M, Marten, MR, Martin, SJ, Martinand-Mari, C, Martinet, W, Martinez-Vicente, M, Masini, M, Matarrese, P, Matsuo, S, Matteoni, R, Mayer, A, Mazure, NM, McConkey, DJ, McConnell, MJ, McDermott, C, McDonald, C, McInerney, GM, McKenna, SL, McLaughlin, B, McLean, PJ, McMaster, CR, McQuibban, GA, Meijer, AJ, Meisler, MH, Meléndez, A, Melia, TJ, Melino, G, Mena, MA, Menendez, JA, Menna-Barreto, RFS, Menon, MB, Menzies, FM, Mercer, CA, Merighi, A, Merry, DE, Meschini, S, Meyer, CG, Meyer, TF, Miao, CY, Miao, JY, Michels, PAM, Michiels, C, Mijaljica, D, Milojkovic, A, Minucci, S, Miracco, C, Miranti, CK, Mitroulis, I, Miyazawa, K, Mizushima, N, Mograbi, B, Mohseni, S, Molero, X, Mollereau, B, Mollinedo, F, Momoi, T, Monastyrska, I, Monick, MM, Monteiro, MJ, Moore, MN, Mora, R, Moreau, K, Moreira, PI, Moriyasu, Y, Moscat, J, Mostowy, S, Mottram, JC, Motyl, T, Moussa, CEH, Müller, S, Muller, S, Münger, K, Münz, C, Murphy, LO, Murphy, ME, Musarò, A, Mysorekar, I, Nagata, E, Nagata, K, Nahimana, A, Nair, U, Nakagawa, T, Nakahira, K, Nakano, H, Nakatogawa, H, Nanjundan, M, Naqvi, NI, Narendra, DP, Narita, M, Navarro, M, Nawrocki, ST, Nazarko, TY, Nemchenko, A, Netea, MG, Neufeld, TP, Ney, PA, Nezis, IP, Nguyen, HP, Nie, D, Nishino, I, Nislow, C, Nixon, RA, Noda, T, Noegel, AA, Nogalska, A, Noguchi, S, Notterpek, L, Novak, I, Nozaki, T, Nukina, N, Nürnberger, T, Nyfeler, B, Obara, K, Oberley, TD, Oddo, S, Ogawa, M, Ohashi, T, Okamoto, K, Oleinick, NL, Oliver, FJ, Olsen, LJ, Olsson, S, Opota, O, Osborne, TF, Ostrander, GK, Otsu, K, Ou, JHJ, Ouimet, M, Overholtzer, M, Ozpolat, B, Paganetti, P, Pagnini, U, Pallet, N, Palmer, GE, Palumbo, C, Pan, T, Panaretakis, T, Pandey, UB, Papackova, Z, Papassideri, I, Paris, I, Park, J, Park, OK, Parys, JB, Parzych, KR, Patschan, S, Patterson, C, Pattingre, S, Pawelek, JM, Peng, J, Perlmutter, DH, Perrotta, I, Perry, G, Pervaiz, S, Peter, M, Peters, GJ, Petersen, M, Petrovski, G, Phang, JM, Piacentini, M, Pierre, P, Pierrefite-Carle, V, Pierron, G, Pinkas-Kramarski, R, Piras, A, Piri, N, Platanias, LC, Pöggeler, S, Poirot, M, Poletti, A, Poüs, C, Pozuelo-Rubio, M, Prætorius-Ibba, M, Prasad, A, Prescott, M, Priault, M, Produit-Zengaffinen, N, Progulske-Fox, A, Proikas-Cezanne, T, Przedborski, S, Przyklenk, K, Puertollano, R, Puyal, J, Qian, SB, Qin, L, Qin, ZH, Quaggin, SE, Raben, N, Rabinowich, H, Rabkin, SW, Rahman, I, Rami, A, Ramm, G, Randall, G, Randow, F, Rao, VA, Rathmell, JC, Ravikumar, B, Ray, SK, Reed, BH, Reed, JC, Reggiori, F, Régnier-Vigouroux, A, Reichert, AS, Reiners, JJ, Reiter, RJ, Ren, J, Revuelta, JL, Rhodes, CJ, Ritis, K, Rizzo, E, Robbins, J, Roberge, M, Roca, H, Roccheri, MC, Rocchi, S, Rodemann, HP, De Córdoba, SR, Rohrer, B, Roninson, IB, Rosen, K, Rost-Roszkowska, MM, Rouis, M, Rouschop, KMA, Rovetta, F, Rubin, BP, Rubinsztein, DC, Ruckdeschel, K, Rucker, EB, Rudich, A, Rudolf, E, Ruiz-Opazo, N, Russo, R, Rusten, TE, Ryan, KM, Ryter, SW, Sabatini, DM, Sadoshima, J, Saha, T, Saitoh, T, Sakagami, H, Sakai, Y, Salekdeh, GH, Salomoni, P, Salvaterra, PM, Salvesen, G, Salvioli, R, Sanchez, AMJ, Sánchez-Alcázar, JA, Sánchez-Prieto, R, Sandri, M, Sankar, U, Sansanwal, P, Santambrogio, L, Saran, S, Sarkar, S, Sarwal, M, Sasakawa, C, Sasnauskiene, A, Sass, M, Sato, K, Sato, M, Schapira, AHV, Scharl, M, Schätzl, HM, Scheper, W, Schiaffino, S, Schneider, C, Schneider, ME, Schneider-Stock, R, Schoenlein, PV, Schorderet, DF, Schüller, C, Schwartz, GK, Scorrano, L, Sealy, L, Seglen, PO, Segura-Aguilar, J, Seiliez, I, Seleverstov, O, Sell, C, Seo, JB, Separovic, D, Setaluri, V, Setoguchi, T, Settembre, C, Shacka, JJ, Shanmugam, M, Shapiro, IM, Shaulian, E, Shaw, RJ, Shelhamer, JH, Shen, HM, Shen, WC, Sheng, ZH, Shi, Y, Shibuya, K, Shidoji, Y, Shieh, JJ, Shih, CM, Shimada, Y, Shimizu, S, Shintani, T, Shirihai, OS, Shore, GC, Sibirny, AA, Sidhu, SB, Sikorska, B, Silva-Zacarin, ECM, Simmons, A, Simon, AK, Simon, HU, Simone, C, Simonsen, A, Sinclair, DA, Singh, R, Sinha, D, Sinicrope, FA, Sirko, A, Siu, PM, Sivridis, E, Skop, V, Skulachev, VP, Slack, RS, Smaili, SS, Smith, DR, Soengas, MS, Soldati, T, Song, X, Sood, AK, Soong, TW, Sotgia, F, Spector, SA, Spies, CD, Springer, W, Srinivasula, SM, Stefanis, L, Steffan, JS, Stendel, R, Stenmark, H, Stephanou, A, Stern, ST, Sternberg, C, Stork, B, Strålfors, P, Subauste, CS, Sui, X, Sulzer, D, Sun, J, Sun, SY, Sun, ZJ, Sung, JJY, Suzuki, K, Suzuki, T, Swanson, MS, Swanton, C, Sweeney, ST, Sy, LK, Szabadkai, G, Tabas, I, Taegtmeyer, H, Tafani, M, Takács-Vellai, K, Takano, Y, Takegawa, K, Takemura, G, Takeshita, F, Talbot, NJ, Tan, KSW, Tanaka, K, Tanaka, K, Tang, D, Tang, D, Tanida, I, Tannous, BA, Tavernarakis, N, Taylor, GS, Taylor, GA, Taylor, JP, Terada, AS, Terman, A, Tettamanti, G, Thevissen, K, Thompson, CB, Thorburn, A, Thumm, M, Tian, F, Tian, Y, Tocchini-Valentini, G, Tolkovsky, AM, Tomino, Y, Tönges, L, Tooze, SA, Tournier, C, Tower, J, Towns, R, Trajkovic, V, Travassos, LH, Tsai, TF, Tschan, MP, Tsubata, T, Tsung, A, Turk, B, Turner, LS, Tyagi, SC, Uchiyama, Y, Ueno, T, Umekawa, M, Umemiya-Shirafuji, R, Unni, VK, Vaccaro, MI, Valente, EM, Van Den Berghe, G, Van Der Klei, IJ, Van Doorn, WG, Van Dyk, LF, Van Egmond, M, Van Grunsven, LA, Vandenabeele, P, Vandenberghe, WP, Vanhorebeek, I, Vaquero, EC, Velasco, G, Vellai, T, Vicencio, JM, Vierstra, RD, Vila, M, Vindis, C, Viola, G, Viscomi, MT, Voitsekhovskaja, OV, Von Haefen, C, Votruba, M, Wada, K, Wade-Martins, R, Walker, CL, Walsh, CM, Walter, J, Wan, XB, Wang, A, Wang, C, Wang, D, Wang, F, Wang, F, Wang, G, Wang, H, Wang, HG, Wang, HD, Wang, J, Wang, K, Wang, M, Wang, RC, Wang, X, Wang, X, Wang, YJ, Wang, Y, Wang, Z, Wang, ZC, Wang, Z, Wansink, DG, Ward, DM, Watada, H, Waters, SL, Webster, P, Wei, L, Weihl, CC, Weiss, WA, Welford, SM, Wen, LP, Whitehouse, CA, Whitton, JL, Whitworth, AJ, Wileman, T, Wiley, JW, Wilkinson, S, Willbold, D, Williams, RL, Williamson, PR, Wouters, BG, Wu, C, Wu, DC, Wu, WKK, Wyttenbach, A, Xavier, RJ, Xi, Z, Xia, P, Xiao, G, Xie, Z, Xie, Z, Xu, DZ, Xu, J, Xu, L, Xu, X, Yamamoto, A, Yamamoto, A, Yamashina, S, Yamashita, M, Yan, X, Yanagida, M, Yang, DS, Yang, E, Yang, JM, Yang, SY, Yang, W, Yang, WY, Yang, Z, Yao, MC, Yao, TP, Yeganeh, B, Yen, WL, Yin, JJ, Yin, XM, Yoo, OJ, Yoon, G, Yoon, SY, Yorimitsu, T, Yoshikawa, Y, Yoshimori, T, Yoshimoto, K, You, HJ, Youle, RJ, Younes, A, Yu, L, Yu, L, Yu, SW, Yu, WH, Yuan, ZM, Yue, Z, Yun, CH, Yuzaki, M, Zabirnyk, O, Silva-Zacarin, E, David Zacks, E, Zacksenhaus, L, Zaffaroni, N, Zakeri, Z, Zeh, HJ, Zeitlin, SO, Zhang, H, Zhang, HL, Zhang, J, Zhang, JP, Zhang, L, Zhang, L, Zhang, MY, Zhang, XD, Zhao, M, Zhao, YF, Zhao, Y, Zhao, ZJ, Zheng, X, Zhivotovsky, B, Zhong, Q, Zhou, CZ, Zhu, C, Zhu, WG, Zhu, XF, Zhu, X, Zhu, Y, Zoladek, T, Zong, WX, Zorzano, A, Zschocke, J & Zuckerbraun, B 2012, Autophagy, vol 8, no. 4, pp. 445-544. DOI: 10.4161/auto.19496

Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammation
Chen, M, Felix, K & Wang, J 2012, Blood, vol 119, no. 1, pp. 127-36. DOI: 10.1182/blood-2011-06-363994

Regulation of Immune Responses by Spontaneous and T cell-mediated Dendritic Cell Death
Chen, M & Wang, J 2011, Journal of clinical & cellular immunology, vol S3. DOI: 10.4172/2155-9899.S3-005

Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells
Chen, M, Felix, K & Wang, J 2011, Journal of Immunology, vol 187, no. 11, pp. 5684-92. DOI: 10.4049/jimmunol.1101834

Programmed cell death of dendritic cells in immune regulation
Chen, M & Wang, J 2010, Immunological Reviews, vol 236, pp. 11-27. DOI: 10.1111/j.1600-065X.2010.00916.x

Selective mitochondrial autophagy during erythroid maturation
Chen, M, Sandoval, H & Wang, J 2008, Autophagy, vol 4, no. 7, pp. 926-8.

Essential role for Nix in autophagic maturation of erythroid cells
Sandoval, H, Thiagarajan, P, Dasgupta, SK, Schumacher, A, Prchal, JT, Chen, M & Wang, J 2008, Nature, vol 454, no. 7201, pp. 232-5. DOI: 10.1038/nature07006

Delineation of the caspase-9 signaling cascade
Guerrero, AD, Chen, M & Wang, J 2008, Apoptosis, vol 13, no. 1, pp. 177-86. DOI: 10.1007/s10495-007-0139-8

Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members
Chen, M, Guerrero, AD, Huang, L, Shabier, Z, Pan, M, Tan, T-H & Wang, J 2007, The Journal of biological chemistry, vol 282, no. 46, pp. 33888-95. DOI: 10.1074/jbc.M702969200

Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity
Chen, M, Huang, L & Wang, J 2007, Blood, vol 109, no. 10, pp. 4360-7. DOI: 10.1182/blood-2006-11-056424

Regulation of the lifespan in dendritic cell subsets
Chen, M, Huang, L, Shabier, Z & Wang, J 2007, Molecular immunology, vol 44, no. 10, pp. 2558-65. DOI: 10.1016/j.molimm.2006.12.020

Dendritic cell apoptosis in the maintenance of immune tolerance
Chen, M, Wang, Y-H, Wang, Y, Huang, L, Sandoval, H, Liu, Y-J & Wang, J 2006, Science (New York, N.Y.), vol 311, no. 5764, pp. 1160-4. DOI: 10.1126/science.1122545

Erratum: Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia (Proceedings of the National Academy of Sciences of the United States of America (April 13, 1999) 96, 8 (4552-4557))
Martin, DA, Zheng, L, Siegel, RM, Huang, B, Fisher, GH, Wang, J, Jackson, CE, Puck, JM, Dale, J, Straus, SE, Peter, ME, Krammer, PH, Fesik, S & Lenardo, MJ 2004, Proceedings of the National Academy of Sciences of the United States of America, vol 101, no. 20, pp. 7840. DOI: 10.1073/pnas.0402364101