James C. Major, MD, PhD

Assistant Professor of Clinical Ophthalmology, Institute for Academic Medicine
Houston Methodist
Weill Cornell Medical College


Education & Training

Clinical Fellowship , Bascom Palmer Eye Inst & Hosp
Residency , Bascom Palmer Eye Inst & Hosp
Internship , Carilion Roanoke Memorial Hospital
MD , Baylor College of Medicine
Publications

THE ASSOCIATION OF EPIRETINAL MEMBRANE WITH MACULAR HOLE FORMATION AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR
Khurana, RN, Wykoff, CC, Bansal, AS, Akiyama, K, Palmer, JD, Chen, E, Chang, LK, Major, JC, Wu, C, Wang, R, Croft, DE & Wong, TP 2016, Retina. DOI:

Choroidal Neovascularization Secondary to Alexandrite Laser Exposure
Wang, R, Wykoff, CC, Christie, L, Croft, DE, Major, JC, Fish, RH & Brown, DM 2016, Retinal Cases and Brief Reports, vol 10, no. 3, pp. 244-248. DOI:

ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION: Role of Prophylactic Topical Ophthalmic Antibiotics
Li, AL, Wykoff, CC, Wang, R, Chen, E, Benz, MS, Fish, RH, Wong, TP, Major, JC, Brown, DM, Schefler, AC, Kim, RY & OMalley, RE 2015, Retina. DOI:

Diagnostic and Therapeutic Challenges
Phillis, CA, Bourke, RD & Major, JC 2015, Retina. DOI:

Aflibercept for pigment epithelial detachment for previously treated neovascular age-related macular degeneration
Major, JC , Wykoff, CC, Croft, DE, Wang, R, Mariani, AF, Lehmann, AE & Brown, DM 2015, Canadian Journal of Ophthalmology, vol 50, no. 5, 715, pp. 373-377. DOI:

5Q with James C. Major Jr, MD, PHD
Major, JC 2015, Retina Today, vol 2015, no. September2015, pp. 81-82.

Progressive retinal nonperfusion in ischemic central retinal vein occlusion
Wykoff, CC , Brown, DM, Croft, DE, Major, JC & Wong, TP 2015, Retina, vol 35, no. 1, pp. 43-47. DOI:

Comparison of spectral-domain and time-domain optical coherence tomography in the detection of neovascular age-related macular degeneration activity
Major, JC , Wykoff, CC, Mariani, AF, Chen, E, Croft, DE & Brown, DM 2014, Retina, vol 34, no. 1, pp. 48-54. DOI:

Purtscher-like retinopathy associated with pemphigus vulgaris
Mariani, AF, Major, JC, Brown, DM, Wykoff, CC, Benz, MS & Kegley, EN 2013, Retinal Cases and Brief Reports, vol 7, no. 4, pp. 304-306. DOI:

Current concepts in managing wet AMD suboptimally responsive to anti-VEGF therapy
Hariprasad, SM & Major, JC 2013, Ophthalmic Surgery Lasers and Imaging Retina, vol 44, no. 3, pp. 225-226. DOI:

SAVE (super-dose anti-VEGF) trial: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration: 1-year results
Wykoff, CC , Brown, DM , Chen, E , Major, JC, Croft, DE, Mariani, A & Wong, TP 2013, Ophthalmic Surgery Lasers and Imaging Retina, vol 44, no. 2, pp. 121-126. DOI:

Super-dose anti-VEGF (SAVE) trial: 2.0 mg Intravitreal ranibizumab for recalcitrant neovascular macular degeneration-primary end point
Brown, DM , Chen, E, Mariani, A & Major, JC 2013, Ophthalmology, vol 120, no. 2, pp. 349-354. DOI:

Use of nepafenac (Nevanac®)in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections
Chen, E, Benz, MS, Fish, RH, Brown, DM, Wong, TP, Kim, RY & Major, JC 2010, Clinical Ophthalmology, vol 4, no. 1, pp. 1249-1252. DOI:

Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the "flying saucer" sign)
Chen, E , Brown, DM, Benz, MS, Fish, RH, Wong, TP, Kim, RY & Major, JC 2010, Clinical Ophthalmology, vol 4, no. 1, pp. 1151-1158. DOI:

Retinal detachment despite aggressive management of aggressive posterior retinopathy of prematurity.
Suk, KK, Berrocal, AM, Murray, TG, Rich, R, Major, JC, Hess, D & Johnson, RA 2010, Journal of pediatric ophthalmology and strabismus, vol 47 Online.

Retinal structure of birds of prey revealed by ultra-high resolution spectral-domain optical coherence tomography
Ruggeri, M, Major, JC, McKeown, C, Knighton, RW, Puliafito, CA & Jiao, S 2010, Investigative Ophthalmology and Visual Science, vol 51, no. 11, pp. 5789-5795. DOI:

Staphylococcus aureus Endophthalmitis: Antibiotic Susceptibilities, Methicillin Resistance, and Clinical Outcomes
Major, JC, Engelbert, M, Flynn, HW, Miller, D, Smiddy, WE & Davis, JL 2010, American Journal of Ophthalmology, vol 149, no. 2. DOI:

Ultra high-resolution optical coherence tomography for ocular imaging of small animals
Ruggeri, M, Jiao, S, Major, JC, Cebulla, C, Rosenfeld, P, Gregori, G, Tsechpenakis, G, Wang, J, Murray, T & Porciatti, V 2009, . in IFMBE Proceedings. vol. 24, pp. 11-12, 25th Southern Biomedical Engineering Conference 2009, Miami, FL, United States, 15-17 May. DOI:

Ultra high-resolution optical coherence tomography for non-contact ocular imaging of small animals
Ruggeri, M, Wehbe, H, Jiao, S, Wang, J, Jockovich, ME, Rosenfeld, PJ, Major, JC, McKeown, C & Puliafito, CA 2008, . in Biomedical Optics, BIOMED 2008. Biomedical Optics, BIOMED 2008, St. Petersburg, FL, United States, 16-19 March.

In vivo imaging of raptor retina with ultra high resolution spectral domain optical coherence tomography
Ruggeri, M, Major, JC, McKeown, C, Wehbe, H, Jiao, S & Puliafito, CA 2008, . in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6844, 684402, Ophthalmic Technologies XVIII, San Jose, CA, United States, 19-21 January. DOI: