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Christof Karmonik, PhD

Associate Research Professor of Translational Imaging, Institute for Academic Medicine
Associate Research Member & Director, MRI Core, Research Institute
Houston Methodist
Weill Cornell Medical College

Research Lab

After completing his postdoctoral training in 2000, Dr. Karmonik joined the faculty at the Baylor College of Medicine in Houston, Texas as Instructor in the Department of Medicine. He became an Assistant Professor in the Department of Radiology there in 2002. In addition to his academic appointments, Dr. Karmonik was also a senior software engineer for the Schlumberger Companies. He joined Houston Methodist Hospital and Research Institute in 2005.

Description of Research

Dr. Karmonik’s research focuses on enhancing information in medical images by optimized acquisition techniques and advanced post-processing algorithms. Applications include visualization and quantification of hemodynamics in cerebral aneurysms to optimize outcome after flow diverter treatment using 4D phase contrast MRI and computational fluid dynamics together with 3D printing technology, understanding flow changes in the ascending aorta in patients with left ventricular flow devices and probing functional connectivity in the brain in health and disease. 

Areas Of Expertise

functional Magnetic Resonance Computational Fluid Dynamics Computational Surgery Brain imaging Image Processing
Education & Training

Visiting Research Fellowship , National Institute of Standards and Technology
Postdoctoral Fellowship , University of Texas MD Anderson Cancer Center
MS , University of the Saarland
PhD , University of the Saarland

Elevated Wall Shear Stress in Aortic Type B Dissection May Relate to Retrograde Aortic Type A Dissection: A Computational Fluid Dynamics Pilot Study
Osswald, A, Karmonik, C, Anderson, JR, Rengier, F, Karck, M, Engelke, J, Kallenbach, K, Kotelis, D, Partovi, S, Böckler, D & Ruhparwar, A 2017, European Journal of Vascular and Endovascular Surgery, vol 54, no. 3, pp. 324-330. DOI: 10.1016/j.ejvs.2017.06.012

Workflow for Visualization of Neuroimaging Data with an Augmented Reality Device
Karmonik, C , Boone, TB & Khavari, R 2017, Journal of Digital Imaging, pp. 1-6. DOI: 10.1007/s10278-017-9991-4

4D Phase Contrast MRI Protocol Optimization using Patient-Specific 3D Printed Replicas for In-Vivo Imaging before and after Flow Diverter Placement
Karmonik, C, Anderson, JR, Elias, S, Klucznik, R, Diaz, O, Zhang, YJ, Grossman, RG & Britz, GW 2017, World Neurosurgery. DOI: 10.1016/j.wneu.2017.06.042

Protocol for a prospective observational study of cortical lower urinary tract control changes following intradetrusor injection of botulinum toxin-A in patients with multiple sclerosis
Elizondo, RA, Karmonik, C, Boone, TB & Khavari, R 2017, BMJ Open, vol 7, no. 2, e013225. DOI: 10.1136/bmjopen-2016-013225

Functional Magnetic Resonance Imaging with Concurrent Urodynamic Testing Identifies Brain Structures Involved in Micturition Cycle in Patients with Multiple Sclerosis
Khavari, R , Karmonik, C, Shy, M, Fletcher, S & Boone, T 2017, The Journal of Urology, vol 197, no. 2, pp. 438-444. DOI: 10.1016/j.juro.2016.09.077

Music Listening Modulates Functional Connectivity and Information Flow in the Human Brain
Karmonik, C, Brandt, A, Anderson, JR, Brooks, F, Lytle, J, Silverman, E & Frazier, JT 2016, Brain Connectivity, vol 6, no. 8, pp. 632-641. DOI: 10.1089/brain.2016.0428

Paramagnetic Gd3+ labeled red blood cells for magnetic resonance angiography
Aryal, S, Stigliano, C, Key, J, Ramirez, M, Anderson, J, Karmonik, C, Fung, S & Decuzzi, P 2016, Biomaterials, vol 98, pp. 163-170. DOI: 10.1016/j.biomaterials.2016.05.002

Imagerie de la dissection aortique de type B : ce que veut savoir le chirurgien avant et après l'intervention
Ohana, M, Labani, A, Georg, Y, Jeung, MY, Thaveau, F, Schwein, A, Karmonik, C, Bismuth, J, Chakfé, N & Roy, C 2016, Journal des Maladies Vasculaires, vol 41, no. 4, pp. 260-271. DOI: 10.1016/j.jmv.2016.05.005

Three-dimensional printing of anatomically accurate, patient specific intracranial aneurysm models
Anderson, JR, Thompson, WL, Alkattan, AK, Diaz, O, Klucznik, R, Zhang, YJ, Britz, GW, Grossman, RG & Karmonik, C 2016, Journal of NeuroInterventional Surgery, vol 8, no. 5, pp. 517-520. DOI: 10.1136/neurintsurg-2015-011686

Design and optimization of an EEG-based brain machine interface (BMI) to an upper-limb exoskeleton for stroke survivors
Bhagat, NA, Venkatakrishnan, A, Abibullaev, B, Artz, EJ, Yozbatiran, N, Blank, AA, French, J, Karmonik, C, Grossman, RG, OMalley, MK, Francisco, GE & Contreras-Vidal, JL 2016, Frontiers in Neuroscience, vol 10, no. MAR, 122. DOI: 10.3389/fnins.2016.00122

Development of a Severe Mitral Valve Stenosis Secondary to the Treatment of Mitral Regurgitation with a Single MitraClip
Osswald, A, Al Jabbari, O, Abu Saleh, WK, Barker, C, Ruhparwar, A, Karmonik, C & Loebe, M 2016, Journal of Cardiac Surgery, vol 31, no. 3, pp. 153-155. DOI: 10.1111/jocs.12692

Morphological and hemodynamic discriminators for rupture status in posterior communicating artery aneurysms
Lv, N, Wang, C, Karmonik, C, Fang, Y, Xu, J, Yu, Y, Cao, W, Liu, J & Huang, Q 2016, PloS one, vol 11, no. 2, e0149906. DOI: 10.1371/journal.pone.0149906

EEG Source Imaging Guided by Spatiotemporal Specific fMRI: Toward an Understanding of Dynamic Cognitive Processes
Nguyen, T, Potter, T, Nguyen, T, Karmonik, C, Grossman, R & Zhang, Y 2016, Neural Plasticity, vol 2016, 4182483. DOI: 10.1155/2016/4182483

The effect of SOM size and similarity measure on identification of functional and anatomical regions in fMRI data
O’Driscoll, P, Merényi, E, Karmonik, C & Grossman, R 2016, . in Advances in Intelligent Systems and Computing. vol. 428, Advances in Intelligent Systems and Computing, vol. 428, Springer Verlag, pp. 251-263, 11th International on Advances in Self-Organizing Maps and Learning Vector Quantization Workshop, WSOM 2016, Houston, United States, 1/6/16. DOI: 10.1007/978-3-319-28518-4_22

Morphological Risk Factors for Rupture of Small (
Lv, N, Feng, Z, Wang, C, Cao, W, Fang, Y, Karmonik, C, Liu, J & Huang, Q 2015, World Neurosurgery. DOI: 10.1016/j.wneu.2015.12.055

Influence of outflow cannula geometry on hemodynamics in patients with partial circulatory support: A computational fluid dynamics (CFD)-study
Engelke, J, Popov, A-F, Partovi, S, Karck, M, Karmonik, C, Simon, AR, Rengier, F & Ruhparwar, A 2015, Journal of Cardiothoracic Surgery, vol 10 Suppl 1, pp. A95. DOI: 10.1186/1749-8090-10-S1-A95

Elevated Pressures on Aortic Valve Leaflets correlate with Orientation of LVAD Outflow Graft
Karmonik, C, Kassi, M, Bhimaraj, A, Estep, J, Loebe, M & Chang, S 2015, Journal of Cardiothoracic Surgery, vol 10 Suppl 1, pp. A356. DOI: 10.1186/1749-8090-10-S1-A356

Hemodynamic and morphological characteristics of unruptured posterior communicating artery aneurysms with oculomotor nerve palsy
Lv, N, Yu, Y, Xu, J, Karmonik, C, Liu, J & Huang, Q 2015, Journal of neurosurgery, pp. 1-5. DOI: 10.3171/2015.6.JNS15267

Relationships and redundancies of selected hemodynamic and structural parameters for characterizing virtual treatment of cerebral aneurysms with flow diverter devices
Karmonik, C, Anderson, JR, Beilner, J, Ge, JJ, Partovi, S, Klucznik, RP, Diaz, O, Zhang, YJ, Britz, GW, Grossman, RG, Lv, N & Huang, Q 2015, Journal of Biomechanics. DOI: 10.1016/j.jbiomech.2015.11.035

Quantification of velocity reduction after flow diverter placement in intracranial aneurysm: An ex vivo study with 3D printed replicas
Anderson, JR, Klucznik, R, Diaz, O, Zhang, YJ, Britz, GW, Grossman, RG & Karmonik, C 2015, . in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. vol. 2015-November, 7320077, IEEE, pp. 7300-7303, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 8/25/15. DOI: 10.1109/EMBC.2015.7320077