Nantz National Alzheimer's Center

Alzheimer's is one of the most common neurodegenerative diseases, robbing those affected of their independence, cherished memories, and, ultimately, their lives. .Since its inception in 2011, the Nantz National Alzheimer Center (NNAC) has become a world-renowned referral center, treating thousands of patients each year. Its goal: slow memory loss progression and improve the quality of life for every patient.

The NNAC provides an environment of comprehensive, compassionate care for patients and their families. The center's interdisciplinary team thoroughly evaluates each patient to ensure all medical conditions affecting memory loss, including hydrocephalus, vascular disease and sleep disorders, are diagnosed and treated. This approach has resulted in dramatic improvements in cognition for many patients.

The center is led by Director Joseph C. Masdeu, MD, PhD, and is part of the Houston Methodist Neurological Institute, led by directors Stanley Appel, MD, chair of the Department of Neurology and Gavin Britz, MBBCh chair of the Department of Neurosurgery. The institute brings together experts in neurology, neurosurgery, neuroradiology, neurophysiology, physical medicine and rehabilitation to provide multidisciplinary perspectives on dementia-related illnesses. 

Hear Janice's story: How Alzheimer's affects families

Research and Clinical Trials
Dr. Philip Noble, Ph.D. research study on Alzheimer's disease

Our interdisciplinary teams combine forces to understand the underlying disease process that causes the death of brain cells, including discovering how to target the beta amyloid plaques that are the hallmark of the disease, preventing the tau protein from tangling, exploring the role inflammation plays in Alzheimer’s, uncovering the connection between cardiovascular conditions and Alzheimer’s disease and creating ways to reduce the drug-development cycle.  

Learn more about our research> 

How to Participate

Using neuroimaging techniques, we study the brain of healthy people and of people with diseases leading to dementia or who are predisposed to them. These studies are critical to discover new and better treatments for these diseases. If you or someone close to you is interested in participating in our studies, please call 713-441-1150 or e-mail

Nantz: Calling for a Cure

Jim Nantz: Calling For a Cure For Alzheimer’s Disease
“Hello friends, I’m Jim Nantz,” is a greeting millions of sports fans have heard thousands of times over the last decade and a half. 

Noble Study

You may be interested in participating in the study of a new investigational drug. 

Jim and Courtney Nantz
Emmy Award-winning sports commentator, Jim Nantz and his wife Courtney, partnered with the Houston Methodist Neurological Institute to create the Nantz National Alzheimer Center as a lasting tribute to Jim’s father, Jim Nantz Jr., who battled Alzheimer’s disease for 13 years. As part of their ongoing work with the center, Jim and Courtney work tirelessly to increase funding and generate awareness of the effects of concussions and traumatic brain injuries, as well as dementia disorders and Alzheimer's disease. Learn more>

Houston Methodist Neurological Institute 
6560 Fannin St., Suite 802 
Houston, TX 77030