department of
cardiovascular sciences



The mission of the Department of Cardiovascular Sciences is to generate great ideas that transform cardiovascular care. In support of this mission, the Department of Cardiovascular Sciences provides resources for scientists and clinical researchers with expertise in cardiovascular and stem cell biology, genetic engineering and lipid metabolism. This enables them to collaborate and translate discoveries into clinical advances. The department includes the Center for Cardiovascular Regeneration (CCR) ,which is focused on exploring mechanisms of pluripotency, cardiovascular differentiation and rejuvenation. Another important resource is theRNAcore, which provides mmRNA constructs for induction of pluripotency, directed differentiation, and telomere extension.

The Houston Methodist culture of innovation is rooted in the noble tradition of translational medicine practiced by the renowned cardiovascular surgeon Dr. Michael DeBakey, whose innovations in cardiovascular surgery at Houston Methodist revolutionized patient care around the world. This work is being continued to date by our physicians and scientists who are advancing the practice of cardiovascular medicine, cardiothoracic surgery, and vascular surgery.
department chair

John P. Cooke, MD, PhD
Joseph C. “Rusty” Walter and Carole Walter Looke Presidential Distinguished Chair in Cardiovascular Disease Research 
Houston Methodist

common antacid increases heart attack risk 

New study by Houston Methodist and Stanford University scientists reports 16-21% increase in heart attack risk with the  use of common antacids. Learn more.


 medtronic corevalve

Michael Reardon, MD, discusses the results from the Medtronic CoreValve U.S. Pivotal High Risk Trial at the American College of Cardiology meeting. Learn more.

cell transdifferentiation

Scientists transform human scar cells into blood vessel cells — discover a new way to repair damaged tissue in Circulation. Learn more.