About ALS
U.S. PATIENTS:713.441.3760
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Houston Methodist is home to the nation’s first multidisciplinary ALS Clinic . The compassionate specialists who comprise “Team Hope” offer innovative, personalized care to patients from throughout the U.S., in collaboration with the Muscular Dystrophy Association (MDA) and the ALS Association (ALSA).
Amyotrophic lateral sclerosis or ALS (also known as Lou Gehrig’s disease or motor neuron disease) is a neuromuscular disorder that causes muscle weakness and interferes with a patient’s ability to function physically. The nerve cells that control movement of muscles gradually die and muscles progressively weaken and atrophy.
Symptoms vary among patients and grow more severe over time. Early diagnosis is key to preserving function and quality of life — the more we know about your condition, the better we can customize your care plan.
Symptoms of ALS
ALS causes loss of upper and lower motor neurons — nerve cells that project from the brain to the spinal cord and from the spinal cord to the muscles. Approximately 20% of patients first notice reduced ability to speak. Muscle weakness eventually becomes the most intense symptom.
Over time, patients may experience a range of symptoms that progressively become worse:
- Cramps in arms, shoulders and tongue
- Difficulty holding their head up or maintaining good posture
- Trouble walking
- Twitching in the arms and legs
- Limited dexterity in the hands
- Weakness in legs, feet or ankles
- Slurring of speech or trouble swallowing
Pain is uncommon with ALS, and the condition usually does not affect cognition, the senses, sexual function or bowel and bladder control. However, ALS slowly diminishes the ability to control the muscles used to move, speak, eat and breathe. Most patients experience progressive muscle weakness over a three-to-five-year time frame.