Coagulation

Clinical Coagulation Specialty Testing

More information including sample requirements can be found in our Searchable Test Catalog.

Test Request Form

Please download and fill out an HMDL Coagulation Test Requisition. Place the sample and test request form in a sealed specimen bag.

Routine Coagulation Testing

• Prothrombin Time (PT)
• Partial Thromboplastin Time (PTT)
• Thrombin Time (TT)
• Fibrinogen
• D-dimer, quantitative
• 1:1 mix (PT and PTT), with interpretation

Factor Assays

• Factor II Activity
• Factor V Activity
• Factor VII Activity
• Factor VIII Activity
• Factor IX Activity
• Factor X Activity
• Factor XI Activity

Thrombophilia Assays

• Antithrombin Activity
• Protein C Activity
• Protein S Activity
• Protein S Free Antigen
• Protein S Total Antigen
• Factor V Leiden Mutation
• Factor II (Prothrombin) Mutation
• Lupus Inhibitor

Anticoagulant Monitoring

• Direct Thrombin Inhibitor Activity (Dabigatran, Bivalirudin, Argatroban)
• Unfractionated Heparin Activity (anti-Xa)
• Low Molecular Weight Heparin Activity (anti-Xa)
• Fondaparinux Activity (anti-Xa)
• Rivaroxaban (Xarelto) Activity (anti-Xa)

Platelet Function Studies (patients must have blood drawn at Houston Methodist Hospital)

• Platelet Aggregation
• If possible please download and have the patient answer the Platelet Aggregation Assay – Patient Questionnaire and send with the patient or sample when ordering the test Verify Now P2Y12
• Verify Now Aspirin
• Platelet Function Analyzer

von Willebrand Factor Assays

• von Willebrand Factor Antigen
• von Willebrand Factor Immunofunctional Activity
• von Willebrand Factor Collagen Binding
• von Willebrand Factor Multimers
• von Willebrand Factor Ristocetin Induced Platelet Aggregation (VWD2B)
• Factor VIII Activity