R. M. Ghobrial, MD, PhD, FACS, FRCS

  • Houston Methodist liver transplant surgeon
  • Sherrie and Alan Conover Chair for Excellence in Liver Transplantation, Houston Methodist Hospital Sherrie and Alan Conover Center for Liver Disease & Transplantation
  • Professor of surgery, Weill Cornell Medical College
Media Contact: Amy Rose , 412.613.1428

R. M. Ghobrial, MD, PhD, FACS, FRCS

Request Interview
Media Contact: Amy Rose , 412.613.1428

Areas of Expertise

  • Biliary disease
  • Hepatology
  • Liver biopsy
  • Liver surgery
  • Liver transplant
  • Liver/biliary diseases
  • Transplant surgery

Credentials

BOARD CERTIFICATION
American Board of Surgery
MEDICAL SCHOOL
Cairo University School of Medicine-Cairo, Egypt | 1980
RESIDENCY
University of Texas Health Science Center, Houston, TX
INTERNSHIP
Massachusetts General Hospital, Boston, MA
FELLOWSHIP
Liver Transplant Uni. of California at Los Angeles (UCLA) 96-98

Publications

Disparities in liver transplantation for metabolic dysfunction-associated steatohepatitis-associated hepatocellular carcinoma
Victor, DW, Kodali, S, Noureddin, M, Brombosz, EW, Lopez, A, Basra, T, Graviss, EA, Nguyen, DT, Saharia, A, Connor, AA, Abdelrahim, M, Cheah, YL, Simon, CJ, Hobeika, MJ, Mobley, CM & Ghobrial, RM 2025, , World Journal of Transplantation, vol. 15, no. 3, 101997. https://doi.org/10.5500/wjt.v15.i3.101997

Outcomes for Early Liver Transplantation for Alcohol-associated Liver Disease in High-acuity Liver Transplant Recipients with Alcohol Use Disorder
Meinders, AM, Connor, AA, Ontiveros, J, Elaileh, A, Patel, K, Todd, J, Nottage, DL, Brombosz, EW, Moore, LW, Simon, CJ, Cheah, YL, Hobeika, MJ, Mobley, CM, Saharia, A, Basra, T, Kodali, S, Victor, DW, Lee, BP, Terrault, N, Li, XC, Gaber, AO & Ghobrial, RM 2025, , Transplantation Direct, vol. 11, no. 4, e1776. https://doi.org/10.1097/TXD.0000000000001776

Transplantation for Peri-Hilar and Intrahepatic Cholangiocarcinoma With mTOR Immunosuppression
Semaan, S, Connor, AA, Saharia, A, Kodali, S, Elaileh, A, Patel, K, Soliman, N, Basra, T, Victor, DW, Simon, CJ, Cheah, YL, Hobeika, MJ, Mobley, CM, Dhingra, S, Schwartz, MR, Maqsood, A, Heyne, K, Abdelrahim, M, Li, XC, Javle, M, Vauthey, JN, Gaber, AO & Ghobrial, RM 2025, , Transplantation Proceedings, vol. 57, no. 2, pp. 255-263. https://doi.org/10.1016/j.transproceed.2025.02.001

Neoadjuvant Multiagent Systemic Therapy Approach to Liver Transplantation for Perihilar Cholangiocarcinoma
Soliman, N, Connor, AA, Saharia, A, Kodali, S, Elaileh, A, Patel, K, Semaan, S, Basra, T, Victor, DW, Simon, CJ, Cheah, YL, Hobeika, MJ, Mobley, CM, Divatia, M, Dhingra, S, Schwartz, M, Maqsood, A, Heyne, K, Abdelrahim, M, Javle, M, Vauthey, JN, Gaber, AO & Ghobrial, RM 2025, , Transplantation Direct, vol. 11, no. 3, e1760, pp. e1760. https://doi.org/10.1097/TXD.0000000000001760

Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models
Xiao, X, Du, Y, Sun, S, Su, X, Xing, J, Wang, G, Elzein, SM, Zou, D, Minze, LJ, Mao, Z, Ghobrial, RM, Connor, AA, Chen, W, Zhang, Z & Li, XC 2025, , Journal of Clinical Investigation, vol. 135, no. 4, e183671. https://doi.org/10.1172/JCI183671

Transplant oncology: keeping the patient's perspective in mind
Bachini, M & Ghobrial, RM 2025, , Current opinion in organ transplantation, vol. 30, no. 1, pp. 1-2. https://doi.org/10.1097/MOT.0000000000001186

Sorafenib as Adjuvant Therapy Post-Liver Transplant: A Single-center Experience
Hassanain, H, Connor, AA, Brombosz, EW, Patel, K, Elaileh, A, Basra, T, Kodali, S, Victor, DW, Simon, CJ, Cheah, YL, Hobeika, MJ, Mobley, CM, Saharia, A, Dhingra, S, Schwartz, M, Maqsood, A, Heyne, K, Kaseb, AO, Vauthey, JN, Gaber, AO, Abdelrahim, M & Ghobrial, RM 2025, , Transplantation Direct, vol. 11, no. 2, pp. e1746. https://doi.org/10.1097/TXD.0000000000001746

Transarterial chemoembolisation combined with lenvatinib plus pembrolizumab versus dual placebo for unresectable, non-metastatic hepatocellular carcinoma (LEAP-012): a multicentre, randomised, double-blind, phase 3 study
Kudo, M, Ren, Z, Guo, Y, Han, G, Lin, H, Zheng, J, Ogasawara, S, Kim, JH, Zhao, H, Li, C, Madoff, DC, Ghobrial, RM, Kawaoka, T, Gerolami, R, Ikeda, M, Kumada, H, El-Khoueiry, AB, Vogel, A, Peng, X, Mody, K, Dutcus, C, Dubrovsky, L, Siegel, AB, Finn, RS & Llovet, JM 2025, , The Lancet, vol. 405, no. 10474, pp. 203-215. https://doi.org/10.1016/S0140-6736(24)02575-3

The 2024 ILTS-ILCA consensus recommendations for liver transplantation for HCC and intrahepatic cholangiocarcinoma
Kodali, S, Kulik, L, DAllessio, A, De Martin, E, Hakeem, AR, Lewinska, M, Lindsey, S, Liu, K, Maravic, Z, Patel, MS, Pinato, D, Rammohan, A, Rich, N, Sanduzzi Zamparelli, M, Victor, DW, Vinaxia, C, Brombosz, EW, Villanueva, A, Meyer, T, Selzner, N, Ghobrial, RM, Rela, M, Sapisochin, G, Abdelrahim, M, Agopian, V, Balci, D, Bruix, J, Bekaii-Saab, TS, Berenguer, M, Bhangui, P, Bhoori, S, Chan, ACY, Chan, SL, Chieh, AKW, Durand, F, Eghtesad, B, Elsabbagh, A, Halazun, KJ, Javle, M, Hibi, T, Jung, DH, Khalili, K, Lee, JM, Lewandowski, R, Line, PD, Llovet, JM, Mazzaferro, V, Mas, V, Mehta, N, Morement, H, OKane, G, Paradis, V, Parikh, N, Pillai, A, Polak, W, Pomposelli, J, Rimassa, L, Singal, A, Soin, AS, Tabrizian, P, Toso, C, Valle, J, Vibert, E, Vogel, A, Rossi, JZ, Watt, K & Woods, AW 2025, , Liver Transplantation, vol. 31, no. 6, pp. 815-831. https://doi.org/10.1097/LVT.0000000000000589

The feasibility of personalized and tumor-informed ctDNA assay for early recurrence detection in post-liver transplantation patients with hepatocellular carcinoma.
Abdelrahim, M, Mejia, A, Esmail, A, Barrera-Gutierrez, JC, Ouf, M, Franses, JW, Bhan, I, Kodali, S, Saharia, A, Mahipal, A, Naleid, N, Bridges, C, Tin, A, Brewer, CM, Aushev, VN, Fungtammasan, A, Jurdi, AA, Liu, MC, Ghobrial, RM & He, AR 2025, , Journal of Clinical Oncology, vol. 43, no. 16suppl, pp. e16283-e16283. https://doi.org/10.1200/JCO.2025.43.16suppl.e16283

Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models
Xiao, X, Du, Y, Sun, S, Su, X, Xing, J, Wang, G, Elzein, SM, Zou, D, Minze, LJ, Mao, Z, Ghobrial, RM, Connor, AA, Chen, W, Zhang, Z & Li, XC 2024, , The Journal of clinical investigation, vol. 135, no. 4, e183671. https://doi.org/10.1172/JCI183671, https://doi.org/10.1172/JCI183671

Outcomes of Patients with Hepatocellular Carcinoma Undergoing Liver Transplantation Utilizing Extended Criteria Donor Grafts
Brombosz, EW, Hobeika, MJ, Kodali, S, Connor, AA, Saharia, A, Mobley, CM, Simon, CJ, Cheah, YL, Abdelrahim, M, Victor, DW, Graviss, EA, Nguyen, DT, Moore, LW & Ghobrial, RM 2024, , Transplantation Proceedings, vol. 56, no. 10, pp. 2203-2212. https://doi.org/10.1016/j.transproceed.2024.10.039

Genome-wide association study identifies high-impact susceptibility loci for HCC in North America
Hassan, MM, Li, D, Han, Y, Byun, J, Hatia, RI, Long, E, Choi, J, Kelley, RK, Cleary, SP, Lok, AS, Bracci, P, Permuth, JB, Bucur, R, Yuan, JM, Singal, AG, Jalal, PK, Ghobrial, RM, Santella, RM, Kono, Y, Shah, DP, Nguyen, MH, Liu, G, Parikh, ND, Kim, R, Wu, HC, El-Serag, H, Chang, P, Li, Y, Chun, YS, Lee, SS, Gu, J, Hawk, E, Sun, R, Huff, C, Rashid, A, Amin, HM, Beretta, L, Wolff, RA, Antwi, SO, Patt, Y, Hwang, LY, Klein, AP, Zhang, K, Schmidt, MA, White, DL, Goss, JA, Khaderi, SA, Marrero, JA, Cigarroa, FG, Shah, PK, Kaseb, AO, Roberts, LR & Amos, CI 2024, , Hepatology, vol. 80, no. 1, pp. 87-101. https://doi.org/10.1097/HEP.0000000000000800


Utilization of Immunotherapy as a Neoadjuvant Therapy for Liver Transplant Recipients with Hepatocellular Carcinoma
Abdelrahim, M, Esmail, A, Divatia, MK, Xu, J, Kodali, S, Victor, DW, Brombosz, E, Connor, AA, Saharia, A, Elaileh, A, Kaseb, AO & Ghobrial, RM 2024, , Journal of Clinical Medicine, vol. 13, no. 11, 3068. https://doi.org/10.3390/jcm13113068

Macrophage niche imprinting as a determinant of macrophage identity and function
Kloc, M, Halasa, M & Ghobrial, RM 2024, , Cellular Immunology, vol. 399-400, 104825. https://doi.org/10.1016/j.cellimm.2024.104825

Reunited: A vision for the future
Brown, RS & Ghobrial, RM 2024, , Liver Transplantation, vol. 30, no. 5, pp. 460. https://doi.org/10.1097/LVT.0000000000000347

Proceedings of the 28th Annual Congress of the International Liver Transplantation Society
Shaji Mathew, J, Shingina, A, Khan, MQ, Wilson, E, Syn, N, Rammohan, A, Alconchel, F, Hakeem, AR, Shankar, S, Patel, D, Keskin, O, Liu, J, Nasralla, D, Mazzola, A, Patel, MS, Tanaka, T, Victor, D, Yoon, U, Yoon, YI, Vinaixa, C, Kirchner, V, De Martin, E, Ghobrial, RM & Chadha, R 2024, , Liver Transplantation, vol. 30, no. 5, pp. 544-554. https://doi.org/10.1097/LVT.0000000000000330

Single-center Outcomes After Liver Transplantation With SARS-CoV-2–Positive Donors: An Argument for Increased Utilization
Connor, AA, Adelman, MW, Mobley, CM, Moaddab, M, Erhardt, AJ, Hsu, DE, Brombosz, EW, Sanghvi, M, Lee Cheah, Y, Simon, CJ, Hobeika, MJ, Saharia, AS, Victor, DW, Kodali, S, Basra, T, Graviss, EA, Nguyen, DT, Elsaiey, A, Moore, LW, Nigo, M, Drews, AL, Grimes, KA, Arias, CA, Li, XC, Gaber, AO & Ghobrial, RM 2024, , Transplantation Direct, vol. 10, no. 4, pp. E1590. https://doi.org/10.1097/TXD.0000000000001590

Effect of a Hispanic outreach program on referral and liver transplantation volume at a single center
Kodali, S, Mobley, CM, Brombosz, EW, Lopez, A, Graves, R, Ontiveros, J, Velazquez, M, Saharia, A, Cheah, YL, Simon, CJ, Valverde, C, Brown, A, Corkrean, J, Moore, LW, Graviss, EA, Victor, DW, Maresh, K, Hobeika, MJ, Egwim, C & Ghobrial, RM 2024, , Transplant Immunology, vol. 84, 102034, pp. 102034. https://doi.org/10.1016/j.trim.2024.102034

Languages

  • English