Johnson Center Core Facility

The Ann Kimball & John W. Johnson Center for Cellular Therapeutics is a 5000 sq. ft. facility that includes 1710 sq. ft. of cleanroom space, a dedicated quality control laboratory, support spaces, and material, equipment and cryogenic storage required for GMP operations. Six independent production rooms, furnished with state-of-the-art equipment allow investigators, with support from our expert personnel, to translate laboratory discoveries into cutting-edge cellular therapies for patient care. Combined with a fully-equipped, in-house quality control laboratory for comprehensive testing and release of products, the Johnson Center offers Houston Methodist the ability to deliver new cellular therapies to our patients in the safest, most cost-efficient and rapid manner.

Services
  • Cell processing/manufacturing and cryopreservation
  • Method development and validation
  • Cryostorage
  • Cell characterization
  • Sterility testing
  • Endotoxin testing
  • Mycoplasma testing
  • Autoclave sterilization
  • QC (batch release) and raw materials testing
  • Regulatory consultation

Cell Processing/Manufacturing and Cryopreservation Equipment
  • Sepax C-Pro Cell Processing System
  • CliniMACs PlusCell Depletion and Enrichment System
  • CliniMACs ProdigyAutomated Cell Processing System
  • VIA ThawCB1000
  • Cook RegentecCellseal Automated Thawing DFS
  • TSCD-II Sterile Tubing Welders
  • Carl Zeiss™ Primo Vert™ Inverted Microscopes
  • SEBRA 2380 Tube Sealer Kits
  • NUAire 6ft Biological safety cabinets
  • CO2 incubators
  • ME1002TE Precision Balances
  • VIA Freeze
  • Cryomed Controlled Rate Freezer
  • CryoPlus™ LN2 Vapor Freezers

Quality Control Equipment
  • BioMerieux BACT/ALERT 3D
  • Countess™ II FL Automated Cell Counter
  • CliniMACs Quant Flow Cytometer
  • Endosafe® nexgen-PTS™
  • Synergy HTX Multi-mode Reader
  • Lucetta 2 Luminometer
  • Previ Color Gram
  • BIOFIRE® Mycoplasma Nucleic Acid Amplification Technique (NAT)
  • CFX Opus 96 Touch Real-Time PCR Detection System
  • Mettler Toledo™ Excellence Plus XPE Analytical Balance

Autoclave Equipment
  • AMSCO® 250LS Small Steam Sterilizer