Philip J. Horner, PhD

  • Professor of Neuroregeneration, Houston Methodist Research Institute
  • Scientific Director, Center for Neuroregeneration, Houston Methodist Neurological Institute, Houston Methodist Research Institute
  • Co-director, Houston Methodist Regenerative & Restorative Neurosurgery, Houston Methodist Research Institute
  • Vice Chairman of Research, Houston Methodist department of neurosurgery
  • Principle Investigator, Houston Methodist Neurological Institute Center for Neuroregeneration Neuroplasticity & Repair Lab

Philip J. Horner, PhD

Areas of Expertise

  • Multiple sclerosis
  • Myelin
  • Neural stem cells
  • Neural trauma
  • Optogenetics
  • Regeneration
  • Spinal cord
  • Stroke

Credentials

MS, The Ohio State University
PhD, The Ohio State University
Postdoctoral Fellowship, The Salk Institute for Biological Studies
BS, University of Nevada, Reno

Publications

Complications of epidural spinal stimulation: lessons from the past and alternatives for the future
Taccola, G, Barber, S, Horner, PJ, Bazo, HAC & Sayenko, D 2020, , Spinal Cord, vol. 58, no. 10, pp. 1049-1059. https://doi.org/10.1038/s41393-020-0505-8

Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery
Olmsted, ZT, Stigliano, C, Badri, A, Zhang, F, Williams, A, Koffas, MAG, Xie, Y, Linhardt, RJ, Cibelli, J, Horner, PJ & Paluh, JL 2020, , Scientific Reports, vol. 10, no. 1, 12939. https://doi.org/10.1038/s41598-020-69274-7

Selective Antagonism of A1 Adenosinergic Receptors Strengthens the Neuromodulation of the Sensorimotor Network During Epidural Spinal Stimulation
Taccola, G, Salazar, BH, Apicella, R, Hogan, MK, Horner, PJ & Sayenko, D 2020, , Frontiers in Systems Neuroscience, vol. 14, 44. https://doi.org/10.3389/fnsys.2020.00044

Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury
Peeler, DJ, Luera, N, Horner, PJ, Pun, SH & Sellers, DL 2020, Journal of Controlled Release, vol. 322, pp. 149-156. https://doi.org/10.1016/j.jconrel.2020.03.025

Engineering the ABIO-BIO interface of neurostimulation electrodes using polypyrrole and bioactive hydrogels
Bhat, A, Graham, AR, Trivedi, H, Hogan, MK, Horner, PJ & Guiseppi-Elie, A 2020, , Pure and Applied Chemistry, vol. 92, no. 6, pp. 897-907. https://doi.org/10.1515/pac-2019-1107

Formulation of thrombin-inhibiting hydrogels: Via self-assembly of ionic peptides with peptide-modified polymers
Lee, J, Zhao, T, Peeler, DJ, Lee, DC, Pichon, TJ, Li, D, Weigandt, KM, Horner, PJ, Pozzo, LD, Sellers, DL & Pun, SH 2020, Soft Matter, vol. 16, no. 15, pp. 3762-3768. https://doi.org/10.1039/d0sm00209g

Development of a protocol to assess cell internalization and tissue uptake of magnetic nanoparticles by AC Biosusceptometry
Quini, CC, Próspero, AG, Kondiles, BR, Chaboub, L, Hogan, MK, Baffa, O, Bakuzis, AF, Horner, PJ & Miranda, JRA 2019, , Journal of Magnetism and Magnetic Materials, vol. 473, pp. 527-533. https://doi.org/10.1016/j.jmmm.2018.10.064


Common neuromuscular effects of epidural and transcutaneous lumbar spinal stimulation
Sayenko, D, Dalm, BD, Horner, PJ & Britz, GW 2019, The Spinal Cord Injury Summit, American Spinal Injury Association’s (ASIA) Annual Scientific Meeting, , Hawaii, 2019, Waikiki, United States, 4/2/15 - 4/5/19, .

Optogenetic surface stimulation of the rat cervical spinal cord
Mondello, SE, Sunshine, MD, Fischedick, AE, Dreyer, SJ, Horwitz, GD, Anikeeva, P, Horner, PJ & Moritz, CT 2018, , Journal of Neurophysiology, vol. 120, no. 2, pp. 795-811. https://doi.org/10.1152/jn.00461.2017


Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes
Krencik, R, Seo, K, van Asperen, JV, Basu, N, Cvetkovic, C, Barlas, S, Chen, R, Ludwig, C, Wang, C, Ward, ME, Gan, L, Horner, PJ, Rowitch, DH & Ullian, EM 2017, , Stem Cell Reports, vol. 9, no. 6, pp. 1745-1753. https://doi.org/10.1016/j.stemcr.2017.10.026

Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression
Nivison, MP, Ericson, NG, Green, VM, Bielas, JH, Campbell, JS & Horner, PJ 2017, , Experimental Neurology, vol. 296, pp. 49-61. https://doi.org/10.1016/j.expneurol.2017.07.001

Myelin plasticity, neural activity, and traumatic neural injury
Kondiles, BR & Horner, PJ 2018, , Developmental Neurobiology, vol. 78, no. 2, pp. 108-122. https://doi.org/10.1002/dneu.22540


Fabrication of multipoint side-firing optical fiber by laser micro-ablation
Nguyen, H, Arnob, MMP, Becker, AT, Wolfe, JC, Hogan, MK, Horner, PJ & Shih, WC 2017, , Optics Letters, vol. 42, no. 9, pp. 1808-1811. https://doi.org/10.1364/OL.42.001808


3D Printed Vascularized Device for Subcutaneous Transplantation of Human Islets
Farina, M, Ballerini, A, Fraga, DW, Nicolov, E, Hogan, M, Demarchi, D, Scaglione, F, Sabek, OM, Horner, P, Thekkedath, U, Gaber, OA & Grattoni, A 2017, , Biotechnology Journal, vol. 12, no. 9, 1700169. https://doi.org/10.1002/biot.201700169

Microbubbles and ultrasound increase intraventricular polyplex gene transfer to the brain
Tan, JKY, Pham, B, Zong, Y, Perez, C, Maris, DO, Hemphill, A, Miao, CH, Matula, TJ, Mourad, PD, Wei, H, Sellers, DL, Horner, PJ & Pun, SH 2016, , Journal of Controlled Release, vol. 231, pp. 86-93. https://doi.org/10.1016/j.jconrel.2016.02.003

Targeted axonal import (TAxI) peptide delivers functional proteins into spinal cord motor neurons after peripheral administration
Sellers, DL, Bergen, JM, Johnson, RN, Back, H, Ravits, JM, Horner, PJ & Pun, SH 2016, , Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 9, pp. 2514-2519. https://doi.org/10.1073/pnas.1515526113

Languages

  • English