Philip J. Horner, PhD

  • Professor of Neuroregeneration, Houston Methodist Research Institute
  • Scientific Director, Center for Neuroregeneration, Houston Methodist Neurological Institute, Houston Methodist Research Institute
  • Co-director, Houston Methodist Regenerative & Restorative Neurosurgery, Houston Methodist Research Institute
  • Vice Chairman of Research, Houston Methodist department of neurosurgery
  • Principle Investigator, Houston Methodist Neurological Institute Center for Neuroregeneration Neuroplasticity & Repair Lab

Philip J. Horner, PhD

Areas of Expertise

  • Multiple sclerosis
  • Myelin
  • Neural stem cells
  • Neural trauma
  • Optogenetics
  • Regeneration
  • Spinal cord
  • Stroke


MS, The Ohio State University
PhD, The Ohio State University
Postdoctoral Fellowship, The Salk Institute for Biological Studies
BS, University of Nevada, Reno


Transcriptome of rat subcortical white matter and spinal cord after spinal injury and cortical stimulation
Kondiles, BR, Wei, H, Chaboub, LS, Horner, PJ, Wu, JQ & Perlmutter, SI 2021, , Scientific Data, vol. 8, no. 1, 175.

A wireless spinal stimulation system for ventral activation of the rat cervical spinal cord
Hogan, MK, Barber, SM, Rao, Z, Kondiles, BR, Huang, M, Steele, WJ, Yu, C & Horner, PJ 2021, , Scientific Reports, vol. 11, no. 1, 14900.

Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
Olmsted, ZT, Stigliano, C, Scimemi, A, Wolfe, T, Cibelli, J, Horner, PJ & Paluh, JL 2021, , iScience, vol. 24, no. 8, 102827.

Transcutaneous spinal cord stimulation improves postural stability in individuals with multiple sclerosis
Roberts, BWR, Atkinson, DA, Manson, GA, Markley, R, Kaldis, T, Britz, GW, Horner, PJ, Vette, AH & Sayenko, DG 2021, , Multiple Sclerosis and Related Disorders, vol. 52, 103009.

A micro-LED implant and technique for optogenetic stimulation of the rat spinal cord
Mondello, SE, Pedigo, BD, Sunshine, MD, Fischedick, AE, Horner, PJ & Moritz, CT 2021, , Experimental Neurology, vol. 335, 113480.

Neural Stimulation and Molecular Mechanisms of Plasticity and Regeneration: A Review
Hogan, MK, Hamilton, GF & Horner, PJ 2020, , Frontiers in Cellular Neuroscience, vol. 14, 271.

Complications of epidural spinal stimulation: lessons from the past and alternatives for the future
Taccola, G, Barber, S, Horner, PJ, Bazo, HAC & Sayenko, D 2020, , Spinal Cord, vol. 58, no. 10, pp. 1049-1059.

Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery
Olmsted, ZT, Stigliano, C, Badri, A, Zhang, F, Williams, A, Koffas, MAG, Xie, Y, Linhardt, RJ, Cibelli, J, Horner, PJ & Paluh, JL 2020, , Scientific Reports, vol. 10, no. 1, 12939.

Selective Antagonism of A1 Adenosinergic Receptors Strengthens the Neuromodulation of the Sensorimotor Network During Epidural Spinal Stimulation
Taccola, G, Salazar, BH, Apicella, R, Hogan, MK, Horner, PJ & Sayenko, D 2020, , Frontiers in Systems Neuroscience, vol. 14, 44.

Engineering the ABIO-BIO interface of neurostimulation electrodes using polypyrrole and bioactive hydrogels
Bhat, A, Graham, AR, Trivedi, H, Hogan, MK, Horner, PJ & Guiseppi-Elie, A 2020, , Pure and Applied Chemistry, vol. 92, no. 6, pp. 897-907.

Formulation of thrombin-inhibiting hydrogels: Via self-assembly of ionic peptides with peptide-modified polymers
Lee, J, Zhao, T, Peeler, DJ, Lee, DC, Pichon, TJ, Li, D, Weigandt, KM, Horner, PJ, Pozzo, LD, Sellers, DL & Pun, SH 2020, , Soft Matter, vol. 16, no. 15, pp. 3762-3768.

Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury
Peeler, DJ, Luera, N, Horner, PJ, Pun, SH & Sellers, DL 2020, , Journal of Controlled Release, vol. 322, pp. 149-156.

Quantification of Myelinated Nerve Fraction and Degeneration in Spinal Cord Neuropil by SHIFT MRI
Wolfe, T, Hoffman, K, Hogan, MK, Salazar, B, Tang, X, Chaboub, L, Quini, CC, Lu, ZL & Horner, PJ 2021, , Journal of Magnetic Resonance Imaging, vol. 53, no. 4, pp. 1162-1174.

Development of a protocol to assess cell internalization and tissue uptake of magnetic nanoparticles by AC Biosusceptometry
Quini, CC, Próspero, AG, Kondiles, BR, Chaboub, L, Hogan, MK, Baffa, O, Bakuzis, AF, Horner, PJ & Miranda, JRA 2019, , Journal of Magnetism and Magnetic Materials, vol. 473, pp. 527-533.

Common neuromuscular effects of epidural and transcutaneous lumbar spinal stimulation
Sayenko, D, Dalm, BD, Horner, PJ & Britz, GW 2019, The Spinal Cord Injury Summit, American Spinal Injury Association’s (ASIA) Annual Scientific Meeting, , Hawaii, 2019, Waikiki, United States, 4/2/15 - 4/5/19, .

Optogenetic surface stimulation of the rat cervical spinal cord
Mondello, SE, Sunshine, MD, Fischedick, AE, Dreyer, SJ, Horwitz, GD, Anikeeva, P, Horner, PJ & Moritz, CT 2018, , Journal of Neurophysiology, vol. 120, no. 2, pp. 795-811.

Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes
Krencik, R, Seo, K, van Asperen, JV, Basu, N, Cvetkovic, C, Barlas, S, Chen, R, Ludwig, C, Wang, C, Ward, ME, Gan, L, Horner, PJ, Rowitch, DH & Ullian, EM 2017, , Stem Cell Reports, vol. 9, no. 6, pp. 1745-1753.


  • English