Lidong Qin, PhD

  • Professor of Nanomedicine, Houston Methodist Research Institute

Lidong Qin, PhD

Areas of Expertise

  • Cancer cell biology
  • Cancer nanotechnology
  • Development of nonconventional technology platforms for cancer diagnosis and risk analysis
  • Microfluidics
  • Nanomedicine
  • Regenerative medicine
  • Translational cancer medicine


MS, Jilin University
Postdoctoral Fellowship, NanoSystems Biology Cancer Center, California Institute of Technology, Pasadena, CA
PhD, Northwestern U.


Evaluation of Single-Cell Cytokine Secretion and Cell-Cell Interactions with a Hierarchical Loading Microwell Chip
Zhou, Y, Shao, N, Bessa de Castro, R, Zhang, P, Ma, Y, Liu, X, Huang, F, Wang, RF & Qin, L 2020, , Cell Reports, vol. 31, no. 4, 107574.

Microfluidic Cell Trap Arrays for Single Hematopoietic Stem/Progenitor Cell Behavior Analysis
Han, X, Ma, Y, Zhang, K, Zhang, P, Shao, N & Qin, L 2019, , Proteomics, vol. n/a, no. n/a.

CRISPR-Cas12a Coupled with Platinum Nanoreporter for Visual Quantification of SNVs on a Volumetric Bar-Chart Chip
Shao, N, Han, X, Song, Y, Zhang, P & Qin, L 2019, Analytical Chemistry, vol. 91, no. 19, pp. 12384-12391.

High-Throughput Isolation of Cell Protrusions with Single-Cell Precision for Profiling Subcellular Gene Expression
Zhang, P, Han, X, Yao, J, Shao, N, Zhang, K, Zhou, Y, Zu, Y, Wang, B & Qin, L 2019, , Angewandte Chemie - International Edition, vol. 58, no. 39, pp. 13700-13705.

Cellular response to moderate chromatin architectural defects promotes longevity
Yu, R, Sun, L, Sun, Y, Han, X, Qin, L & Dang, W 2019, , Science Advances, vol. 5, no. 7, eaav1165.

Integrated Microfluidic Chip for Efficient Isolation and Deformability Analysis of Circulating Tumor Cells
Liu, Z, Chen, R, Li, Y, Liu, J, Wang, P, Xia, X & Qin, L 2018, , Advanced Biosystems, vol. 2, no. 10, 1800200.

Analysis of the bystander effect in cone photoreceptors via a guided neural network platform
Ma, Y, Han, X, De Castro, RB, Zhang, P, Zhang, K, Hu, Z & Qin, L 2018, , Science advances, vol. 4, no. 5, eaas9274.

PD-1 blocks lytic granule polarization with concomitant impairment of integrin outside-in signaling in the natural killer cell immunological synapse
Huang, Y, Chen, Z, Jang, JH, Baig, MS, Bertolet, G, Schroeder, C, Huang, S, Hu, Q, Zhao, Y, Lewis, DE, Qin, L, Zhu, MX & Liu, D 2018, , Journal of Allergy and Clinical Immunology, vol. 142, no. 4, pp. 1311-1321.e8.

Immunological Synapse Predicts Effectiveness of Chimeric Antigen Receptor Cells
Xiong, W, Chen, Y, Kang, X, Chen, Z, Zheng, P, Hsu, YH, Jang, JH, Qin, L, Liu, H, Dotti, G & Liu, D 2018, , Molecular Therapy, vol. 26, no. 4, pp. 963-975.

Microfluidics Cell Loading-Dock System: Ordered Cellular Array for Dynamic Lymphocyte-Communication Study
Li, Y, Jang, JH, Wang, C, He, B, Zhang, K, Zhang, P, Vu, T & Qin, L 2017, , Advanced Biosystems, vol. 1, no. 10, 1700085.

Microfluidic Mapping of Cancer Cell-Protein Binding Interaction
Liu, Z, Han, X, Chen, R, Zhang, K, Li, Y, Fruge, S, Jang, JH, Ma, Y & Qin, L 2017, , ACS Applied Materials and Interfaces, vol. 9, no. 27, pp. 22143-22148.

Integrated Microfluidic System for Gene Silencing and Cell Migration
Liu, Z, Han, X, Zhou, Q, Chen, R, Fruge, S, Jo, MC, Ma, Y, Li, Z, Yokoi, K & Qin, L 2017, , Advanced Biosystems, vol. 1, no. 6.

Highly efficient genome editing of human hematopoietic stem cells via a nano-silicon-blade delivery approach
Ma, Y, Han, X, Quintana Bustamante, O, Bessa De Castro, R, Zhang, K, Zhang, P, Li, Y, Liu, Z, Liu, X, Ferrari, M, Hu, Z, Carlos Segovia, J & Qin, L 2017, , Integrative Biology (United Kingdom), vol. 9, no. 6, pp. 548-554.

Bridging the gap: microfluidic devices for short and long distance cell-cell communication
Vu, TQ, De Castro, RMB & Qin, L 2017, , Lab on a Chip, vol. 17, no. 6, pp. 1009-1023.


  • English
  • Chinese