Houston Methodist Division of Benign Hematology

The Houston Methodist Division of Benign Hematology excels in the diagnosis and treatment of non-malignant hematologic disorders. We work closely with all Houston Methodist Centers of Excellence including: the DeBakey Heart & Vascular Center, the J.C. Walter Jr. Transplant Center, the Lynda K. and David M. Underwood Center for Digestive Health, the Neurological Institute and Orthopedics & Sports Medicine. Our division ensures comprehensive patient care through collaboration with the malignant hematological specialists at the Houston Methodist Neal Cancer Center, hospitalists and with our dedicated teaching service. 

 

We are set apart by the wide range of blood disorders we manage, including Congenital TTP, Paroxysmal nocturnal hemoglobinuria (PNH) and Evans’ syndrome. Our hematologists provide answers and hope for patients whose disorders were misdiagnosed or previously unseen.  

 

We provide stewardship through our work on the system wide anticoagulation committee and the venous thromboembolism prevention task force, where we collaborate with pharmacists, nurses and colleagues form various specialties to guide anticoagulation management and provide unparallel patient safety. 

 

Through the highest level of hematologic clinical care, we conduct groundbreaking research and prioritize the education of the next generation of hematologists. 

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Peer Reviewed Publications

1

Clinical Trials

Our Team

Our nationally and internationally recognized experts in the industry are sought out, particularly for the most complex cases. We are among the most well-versed in both Houston and the nation in the types of disorders that many hematologists have yet to treat. Our team includes part-time collaborators from the Cancer Center. 


Half of the referrals to our division come from hematologists at other institutions and community clinics. Similarly sized clinics may see three or four PNH patients at a time, while we treat roughly 25 patients at the same time. 


Our faculty participate in organizations such as the American Society of Clinical Oncology, the American Society of Hematology, the American College of Physicians, the American Medical Association and the American Osteopathic Association. 


Jenny Petkova, MD leads robust research efforts in congenital coagulopathies and blood clotting disorders and has worked on more claims relating to venous embolism and thrombosis, deep vein thrombosis (DVT) and bleeding disorders than other providers in the area. 


Our Faculty ➝   Our Physicians ➝ 

Our Research

We conduct cutting-edge research on platelet and anemia disorders, and our researchers regularly publish on their numerous studies. Recent clinical studies include participation in pivotal trials of novel platelet-stimulating hormones, anticoagulants and iron-chelators, NASA-funded anemia studies (neocytolysis), erythropoietin research, and trials for drugs like crizanlizumab and deferasirox. 


Our clinicians work with the latest life-changing medications and therapies, including recent registry studies on myeloproliferative neoplasms. We have been a study center for multinational research leading to the approval of practice-changing drugs. Our innovative research has even been conducted on anemia in astronauts for NASA.  


Lawrence Rice, MD, Distinguished Chair in Hematology, is considered a world expert on heparin-induced thrombocytopenia (HIT) and frequently gives lectures and chairs national educational symposia and CME events. Dr. Rice has also received numerous teaching awards, including induction in the inaugural class of the Baylor Medicine Educator Hall of Fame and the Hematology Honorary Fellow (Outstanding Teacher) Award from graduating MD Anderson Hematology/Oncology fellows. 

Heparin-Induced Thrombocytopenia With Very High Antibody Titer Is Associated With Slower Platelet Recovery
This single-institution retrospective study of 116 HIT patients examined the effect of heparin–PF4 OD on time-to-platelet recovery, vascular thrombosis and in-hospital mortality.
Long-Term Outcomes of Light Chain Amyloidosis Patients Receiving Heart Transplant: A Single-Center Experience
Cardiac amyloidosis is a less common indication for orthotopic heart transplantation (OHT). Light chain (AL) amyloidosis specifically poses challenges. We present experience from a large contemporary series at a single center.
Interpreting Coagulation Mixing Study Results in the Era of Direct Oral Anticoagulants
Interpretation of coagulation mixing studies is complicated by interference arising from direct oral anticoagulants (DOACs), which are increasingly prescribed. In this retrospective study, we reviewed 1,035 consecutive coagulation mixing studies.
Neutrophil Production and Kinetics: Neutropenia and Neutrophilia
Changes in neutrophil count are frequently encountered in clinical medicine in that increased or decreased neutrophil counts are often seen with infections and other disorders.

Education & Training

We prioritize the education and training of the next generation of hematologists, including residents, subspecialty fellows and medical students.  

 

Our training leads students to academic medical centers and private practices across the country, where they are recognized as pillars of their communities. Our faculty receive numerous teaching awards such as the Edward C. Lynch Outstanding Teaching Award and Houston Methodist GME Teacher of the Year Award. 

 

Experts in our division train students in the growing Internal Medicine Residency program. ACGME-accredited Hematology-Oncology Fellowship students complete rotations with us as part of their didactic curriculum, which requires six months of benign hematology training. Once a month, fellows do rotations at Legacy Community Health, a federally qualified health center (FQHC) to treat a variety of benign hematologic diseases in underserved populations. 

 

Our training footprint is expansive and extends to MD Anderson Cancer Center fellows and Texas A&M University medical students. Faculty in this division frequently give lectures and chair national educational symposia and CME events. 

For Patients

For Patients

Our hematologists understand how diseases affect blood composition and function. We guide your care from diagnosis to treatment, which may involve medication, lifestyle changes or more advanced therapies such as bone marrow transplants.