Weiming Xia

Weiming Xia, PhD

Associate Affiliate Member, Research Institute
Houston Methodist


Publications

Reduction of Phosphorylated Tau in Alzheimer's Disease Induced Pluripotent Stem Cell-Derived Neuro-Spheroids by Rho-Associated Coiled-Coil Kinase Inhibitor Fasudil
Giunti, E, Collu, R, Daley, S, Querfurth, H, Morin, P, Killick, R, Melamed, RD, Xia, W & Wang, H 2023, , Journal of Alzheimers Disease, vol. 96, no. 4, pp. 1695-1709. https://doi.org/10.3233/JAD-230551

Rule-Based Identification of Individuals with Mild Cognitive Impairment or Alzheimer’s Disease Using Clinical Notes from the United States Veterans Affairs Healthcare System
Aguilar, BJ, Miller, D, Jasuja, G, Li, X, Shishova, E, O’Connor, MK, Nguyen, A, Morin, P, Berlowitz, D, Zhang, R, Monfared, AAT, Zhang, Q & Xia, W 2023, , Neurology and Therapy, vol. 12, no. 6, pp. 2067-2078. https://doi.org/10.1007/s40120-023-00540-2

Angiotensin-converting enzyme inhibitors and statins therapies-induced changes in omics profiles in humans and transgenic tau mice
Collu, R, Giunti, E, Daley, S, Chen, M & Xia, W 2023, , Biomedicine and Pharmacotherapy, vol. 168, 115756. https://doi.org/10.1016/j.biopha.2023.115756

Multimodal Machine Learning for 10-Year Dementia Risk Prediction: The Framingham Heart Study
Ding, H, Mandapati, A, Hamel, AP, Karjadi, C, Ang, TFA, Xia, W, Au, R & Lin, H 2023, , Journal of Alzheimers Disease, vol. 96, no. 1, pp. 277-286. https://doi.org/10.3233/JAD-230496

Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development
Zhou, J, Shi, Q, Ge, YY, He, W, Hu, X, Xia, W & Yan, R 2023, , Human Molecular Genetics, vol. 32, no. 16, pp. 2587-2599. https://doi.org/10.1093/hmg/ddad085

Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy
Kirsch, D, Shah, A, Dixon, E, Kelley, H, Cherry, JD, Xia, W, Daley, S, Aytan, N, Cormier, K, Kubilus, C, Mathias, R, Alvarez, VE, Huber, BR, McKee, AC & Stein, TD 2023, , Journal of Neuropathology and Experimental Neurology, vol. 82, no. 2, pp. 127-139. https://doi.org/10.1093/jnen/nlac122

The mevalonate suppressor d-tocotrienol increases AMPA receptor-mediated neurotransmission
Wei, W, Yount, ST, Allen, ZD, Bechdol, KF, Xia, W, Mo, H & Mabb, AM 2023, , Biochemical and Biophysical Research Communications, vol. 638, pp. 112-119. https://doi.org/10.1016/j.bbrc.2022.11.052

Clinical and Scientific Challenges to Effectiveness Studies Under Coverage with Evidence Development in Alzheimer’s Disease
Morin, PJ, Zhang, Q, Xia, W, Miller, D, Querfurth, H & Tahami Monfared, AA 2023, , Neurology and Therapy, vol. 12, no. 3, pp. 721-726. https://doi.org/10.1007/s40120-023-00462-z

The epidemiology of mild cognitive impairment, Alzheimer's disease and related dementia in U.S. veterans
Dinesh, D, Shao, Q, Palnati, M, McDannold, S, Zhang, Q, Monfared, AAT, Jasuja, GK, Davila, H, Xia, W, Moo, LR, Miller, DR & Palacios, N 2023, , Alzheimers and Dementia, vol. 19, no. 9, pp. 3977-3984. https://doi.org/10.1002/alz.13071

Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles
Alzheimers Disease Neuroimaging Initiative 2023, , Alzheimers and Dementia, vol. 19, no. 11, pp. 5173-5184. https://doi.org/10.1002/alz.13069

Vitreous Humor Biomarkers Reflect Pathological Changes in the Brain for Alzheimer's Disease and Chronic Traumatic Encephalopathy
Vig, V, Garg, I, Tuz-Zahra, F, Xu, J, Tripodis, Y, Nicks, R, Xia, W, Alvarez, VE, Alosco, ML, Stein, TD & Subramanian, ML 2023, , Journal of Alzheimers disease : JAD, vol. 93, no. 3, pp. 1181-1193. https://doi.org/10.3233/JAD-230167

Decreased myelin proteins in brain donors exposed to football-related repetitive head impacts
Alosco, ML, Ly, M, Mosaheb, S, Saltiel, N, Uretsky, M, Tripodis, Y, Martin, B, Palmisano, J, Delano-Wood, L, Bondi, MW, Meng, G, Xia, W, Daley, S, Goldstein, LE, Katz, DI, Dwyer, B, Daneshvar, DH, Nowinski, C, Cantu, RC, Kowall, NW, Stern, RA, Alvarez, VE, Mez, J, Huber, BR, McKee, AC & Stein, TD 2023, , Brain Communications, vol. 5, no. 2, fcad019, pp. fcad019. https://doi.org/10.1093/braincomms/fcad019

Upregulation of Neuroinflammatory Protein Biomarkers in Acute Rhegmatogenous Retinal Detachments
Prasad, M, Xu, J, Agranat, JS, Xia, W, Daley, S, Ness, S, Chen, X, Siegel, NH, Stein, TD, Chung, J & Subramanian, ML 2022, , Life, vol. 13, no. 1, 118. https://doi.org/10.3390/life13010118

Healthcare Resource Utilization Among Veterans with Alzheimer’s Disease
Aguilar, BJ, Li, M, Wang, Y, Morin, P, Berlowitz, D, Monfared, AAT, Zhang, Q & Xia, W 2022, , Alzheimers and Dementia, vol. 18, no. S8, e065661. https://doi.org/10.1002/alz.065661

CD8+ T cells in neurodegeneration: friend or foe?
Hu, D, Xia, W & Weiner, HL 2022, , Molecular Neurodegeneration, vol. 17, no. 1, 59. https://doi.org/10.1186/s13024-022-00563-7

Clinical Staging of Alzheimer’s Disease: Concordance of Subjective and Objective Assessments in the Veteran’s Affairs Healthcare System
Morin, P, Li, M, Wang, Y, Aguilar, BJ, Berlowitz, D, Tahami Monfared, AA, Irizarry, M, Zhang, Q & Xia, W 2022, , Neurology and Therapy, vol. 11, no. 3, pp. 1341-1352. https://doi.org/10.1007/s40120-022-00379-z

Clinical outcomes of COVID-19 infection among patients with Alzheimer's disease or mild cognitive impairment
Wang, Y, Li, M, Kazis, LE & Xia, W 2022, , Alzheimers and Dementia, vol. 18, no. 5, pp. 911-923. https://doi.org/10.1002/alz.12665

Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease
Panitch, R, Hu, J, Xia, W, Bennett, DA, Stein, TD, Farrer, LA & Jun, GR 2022, , Alzheimers Research and Therapy, vol. 14, no. 1, 30, pp. 30. https://doi.org/10.1186/s13195-022-00975-z

A comparison between tau and amyloid-ß cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease
Turk, KW, Geada, A, Alvarez, VE, Xia, W, Cherry, JD, Nicks, R, Meng, G, Daley, S, Tripodis, Y, Huber, BR, Budson, AE, Dwyer, B, Kowall, NW, Cantu, RC, Goldstein, LE, Katz, DI, Stern, RA, Alosco, ML, Mez, J, McKee, AC & Stein, TD 2022, , Alzheimers Research and Therapy, vol. 14, no. 1, 28, pp. 28. https://doi.org/10.1186/s13195-022-00976-y

Laser induced breakdown spectroscopy for the rapid detection of SARS-CoV-2 immune response in plasma
Berlo, K, Xia, W, Zwillich, F, Gibbons, E, Gaudiuso, R, Ewusi-Annan, E, Chiklis, GR & Melikechi, N 2022, , Scientific Reports, vol. 12, no. 1, 1614, pp. 1614. https://doi.org/10.1038/s41598-022-05509-z