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Stanley H. Appel, MD

Neurology, Neuromuscular Medicine

Co-Director Houston Methodist Neurological Institute

Houston Methodist Stanley H. Appel Department of Neurology

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Accepting New Patients

Stanley H. Appel, MD

Co-Director Houston Methodist Neurological Institute

Houston Methodist Stanley H. Appel Department of Neurology

View Faculty Profile

About Me

Stanley H. Appel, MD is Co-director of Houston Methodist Neurological Institute, chair of the Stanley H. Appel Department of Neurology and the Peggy and Gary Edwards Distinguished Chair in ALS at Houston Methodist Hospital. He also is Professor of Neurology at Weill Cornell Medical College.

An internationally renowned researcher and neurologist, Dr. Appel is dedicated to the treatment of patients with ALS and is one of the nation's foremost experts on the disease. He has spent more than 40 years devoted to understanding the human brain. Dr. Appel is creator and director of what is now the Houston Methodist Neurological Institute's MDA/ALSA ALS Research and Clinical Center in Houston. Established in 1982, the center was the first multidisciplinary clinic dedicated to ALS patient care and research in the United States. Dr. Appel's laboratory focuses on developing new insights into ALS, Parkinson's disease, and Alzheimer's disease, and was the first to document regulatory T-lymphocytes modulate disease progression in ALS patients. His focus is on enhancing the protective immunity of T-reg cells and anti-inflammatory microglia in neurodegeneration.

Dr. Appel has written 15 books and more than 400 articles. His achievements include the Gold Medal for Excellence in Biomedical Research from Columbia College of Physicians and Surgeons, Sheila Essey Award for ALS Research, Texas Neurological Society Lifetime Achievement Award, Forbes Norris Award from the International Alliance of ALS/MND Associations and John P. McGovern Compleat Physician Award from the Houston Academy of Medicine.

Clinical Interests

Amyotrophic lateral sclerosis (ALS)
Alzheimer’s disease
Neuromuscular disease
Parkinson’s disease
Multiple system atrophy

Accepted Insurance Plans

90 Degree/Entrust
Aetna Affordable Health Choices
Aetna Choice POS / Open Choice
Aetna Common Spirit Health KelseyCare
Aetna Common Spirit Minimum Value Plan
Aetna CommonSpirit Health KelseyCare
Aetna EPO
Aetna HMO
Aetna Health Network
Aetna International
Aetna Managed Choice / Elect Choice
Aetna Medicare Advantage HMO
Aetna Medicare Advantage PPO
Aetna Meritain Health
Aetna Open Access
Aetna POS
Aetna PPO
Aetna QPOS
Aetna Select
Aetna Signature Administrators
Aetna Signature Administrators Allied Benefits
Aetna Signature Administrators CoreSource
Aetna Signature Administrators TX Annual Conf of UMC
Aetna Student Health
Aetna Transplant
Aetna Workers' Comp
All Saver/United Healthcare
Beech Street PPO
Best Doctors International
Blue Choice POS
Blue Choice PPO
Blue Cross Blue Shield EPO
Blue Cross Blue Shield FEP Federal Employee Plan
Blue Cross Blue Shield Medicare Advantage HMO
Blue Cross Blue Shield Medicare Advantage PPO
Blue Cross Blue Shield POS
Blue Cross Blue Shield PPO
Blue Edge
Blue Essentials
Blue Essentials Access
Care Improvement Plus Medicare Advantage
CareWorks Workers' Comp
Cigna APWU
Cigna Allegiance Houston Methodist Employee Medical Plan
Cigna Allegiance OAP
Cigna Allegiance PPO
Cigna Choice Fund
Cigna EPO
Cigna Global Health Benefits (International)
Cigna Great West
Cigna HMO
Cigna HealthSpring Medicare Advantage HMO
Cigna HealthSpring Medicare Advantage PPO
Cigna Indemnity
Cigna LocalPlus
Cigna NALC
Cigna Network
Cigna Network Open Access
Cigna Open Access
Cigna Open Access Plus (OAP)
Cigna POS
Cigna PPO
Cigna Qualcare
Cigna Shared Administration OAP
Cigna Shared Administration PPO
Cigna SureFit
Community Health Choice Marketplace
Coventry PPO
DEVOTED HEALTH CORE GREATER HOUSTON HMO
DEVOTED HEALTH PRIME GREATER HOUSTON HMO
Erickson Advantage
Evolutions HealthCare PPO
First Health PPO
Galaxy Health Network PPO
GeoBlue
HAA Preferred Partners (International)
HMO Blue
HealthSmart Accel PPO
HealthSmart PPO
HealthSmart Payors Organization
Humana HMO / EPO
Humana Medicare Advantage Choice PPO
Humana Medicare Advantage Gold Plus/Choice
Humana Medicare Advantage HMO
Humana Medicare Advantage PPO
Humana Military TRICARE-East Region
Humana Natl POS Open Access
Humana POS & Preferred POS
Humana PPO & Preferred PPO
Humana/ChoiceCare Network PPO
Humana/ChoiceCare+ Network PPO
Imagine Health
Imagine Health GPA
Imagine Health Trustmark
Imagine Health/SISCO
Independent Medical Systems PPO (IMS)
Kelsey Seybold Affiliate Network
Medica-UnitedHealthcare Choice Plus
Medicare
Medicare Railroad
MultiPlan PPO
National Preferred Provider Network PPO (NPPN)
Olympus Managed Care (International)
Oscar Easy Care Medicare Advantage
PHCS Healthy Directions
PHCS PPO
Provider Select PPO
Reny Company Workers' Comp
Student Assurance Services Student Accident Plan
TRS-ActiveCare 2 Group 385002
TRS-ActiveCare Fully Insured Plan-South Texas Region Group 295430
TRS-ActiveCare Fully Insured Plan-West Texas Region Group 295781
TRS-ActiveCare HD Group 385000
TRS-ActiveCare Primary Group 385003
TRS-ActiveCare Primary Plus Group 385001
TRS-Care Medicare Advantage
TRS-Care Standard ALT A I Group 485002
TRS-Care Standard ALT A II Group 485003
TRS-Care Standard ALT B I Group 485005
TRS-Care Standard ALT B II Group 485006
TRS-Care Standard CMED Group 485001
TRS-Care Standard Group 485000
TexanPlus/Wellcare Medicare Advantage
Texas Kids First /Fidelity Security Student Accident Plan
Texas Monarch/Web TPA Student Accident Plan
Three Rivers Provider Network
UHC Dual Complete MCR
UHC Medicare Chronic Complete
UHC Medicare Complete
UHC Medicare Solutions
UMR
US Family Health Plan
USA Managed Care PPO
United Health Integrated Services
United Healthcare Medicare Advantage
United Healthcare Nexus ACO
United Healthcare Plan of the River Valley
UnitedHealthOne
UnitedHealthcare Choice
UnitedHealthcare ChoicePlus
UnitedHealthcare Core
UnitedHealthcare Core Plus
UnitedHealthcare EPO
UnitedHealthcare Golden Rule
UnitedHealthcare HMO
UnitedHealthcare Navigate
UnitedHealthcare Navigate Plus
UnitedHealthcare Options PPO
UnitedHealthcare Oxford
UnitedHealthcare POS
UnitedHealthcare PPO
UnitedHealthcare Select / ERS
UnitedHealthcare Student Resources
UnitedHealthcare West
WellMed AARP Medicare Advantage Plan
WellMed AARP Medicare Complete
WellMed United Healthcare Dual Complete
Workers Comp-Beech Street
Workers' Comp: Coventry / First Health

Insurance plans may change. Please verify your plan is accepted when scheduling an appointment.

Credentials

BOARD CERTIFICATION
Neurology | American Board of Psychiatry and Neurology
MEDICAL SCHOOL
Columbia University College of Physicians and Surgeons - New York, NY | 1960
INTERNSHIP
Harvard University - Cambridge, MA
RESIDENCY
Neurology | Mount Sinai Medical Center - Miami Beach, FL
RESEARCH FELLOWSHIP
Duke University Medical Center - Durham, NC
AFFILIATED HOSPITALS
  • Houston Methodist Hospital
CENTER MEMBERSHIP
  • Houston Methodist Neurological Institute

Languages

  • English
Languages listed are spoken by doctor and/or office staff.