Stanley H. Appel, MD

Neurology, Neuromuscular Medicine

Houston Methodist Stanley H. Appel Department of Neurology

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Accepting New Patients

Stanley H. Appel, MD

Houston Methodist Stanley H. Appel Department of Neurology

View Faculty Profile

About Me

Stanley H. Appel, MD is Co-director of Houston Methodist Neurological Institute, chair of the Stanley H. Appel Department of Neurology and the Peggy and Gary Edwards Distinguished Chair in ALS at Houston Methodist Hospital. He also is Professor of Neurology at Weill Cornell Medical College.

An internationally renowned researcher and neurologist, Dr. Appel is dedicated to the treatment of patients with ALS and is one of the nation's foremost experts on the disease. He has spent more than 40 years devoted to understanding the human brain. Dr. Appel is creator and director of what is now the Houston Methodist Neurological Institute's MDA/ALSA ALS Research and Clinical Center in Houston. Established in 1982, the center was the first multidisciplinary clinic dedicated to ALS patient care and research in the United States. Dr. Appel's laboratory focuses on developing new insights into ALS, Parkinson's disease, and Alzheimer's disease, and was the first to document regulatory T-lymphocytes modulate disease progression in ALS patients. His focus is on enhancing the protective immunity of T-reg cells and anti-inflammatory microglia in neurodegeneration.

Dr. Appel has written 15 books and more than 400 articles. His achievements include the Gold Medal for Excellence in Biomedical Research from Columbia College of Physicians and Surgeons, Sheila Essey Award for ALS Research, Texas Neurological Society Lifetime Achievement Award, Forbes Norris Award from the International Alliance of ALS/MND Associations and John P. McGovern Compleat Physician Award from the Houston Academy of Medicine.

Clinical Interests

Amyotrophic lateral sclerosis (ALS)
Alzheimer’s disease
Neuromuscular disease
Parkinson’s disease
Multiple system atrophy

Accepted Insurance Plans

AARP Medicare Complete
Aetna Affordable Health Choices
Aetna Choice POS / Open Choice
Aetna EPO
Aetna HMO
Aetna Health Network
Aetna International
Aetna Managed Choice / Elect Choice
Aetna Medicare Advantage HMO
Aetna Medicare Advantage PPO
Aetna Meritain Health
Aetna Open Access
Aetna POS
Aetna PPO
Aetna QPOS
Aetna Select
Aetna Signature Administrators
Aetna Signature Administrators Allied Benefits
Aetna Signature Administrators CoreSource
Aetna Student Health
Aetna Workers' Comp
All Saver/United Healthcare
Axis Global / Texas Monarch Student Accident Plan
Beech Street PPO
Best Doctors International
Blue Choice POS
Blue Choice PPO
Blue Cross Blue Shield EPO
Blue Cross Blue Shield FEP Federal Employee Plan
Blue Cross Blue Shield Medicare Advantage HMO
Blue Cross Blue Shield Medicare Advantage PPO
Blue Cross Blue Shield POS
Blue Cross Blue Shield PPO
Blue Cross Blue Shield Traditional / Par Plan
Blue Edge
Blue Essentials
Blue Essentials Access
CARDIOVASCULAR CARE PROVIDERS
Care Improvement Plus Medicare Advantage
Cigna APWU
Cigna Choice Fund
Cigna EPO
Cigna Global Health Benefits (International)
Cigna Great West
Cigna HMO
Cigna Indemnity
Cigna LocalPlus / Vantage
Cigna NALC
Cigna Network
Cigna Network Open Access
Cigna Open Access
Cigna Open Access Plus (OAP)
Cigna POS
Cigna PPO
Cigna Qualcare
Cigna Shared Administration OAP
Cigna Shared Administration PPO
Community Health Choice Marketplace
Coventry PPO
Crown International
Erickson Advantage
Evolutions HealthCare PPO
First Health PPO
Galaxy Health Network PPO
GeoBlue
HAA Preferred Partners (International)
HMO Blue
HealthSmart Accel PPO
HealthSmart PPO
HealthSmart Payors Organization
Humana HMO / EPO
Humana Medicare Advantage HMO
Humana Medicare Advantage PPO
Humana Medicare Advantage Private Fee For Service
Humana Military TRICARE-South Region
Humana POS & Preferred POS
Humana PPO & Preferred PPO
Humana TRS-Care Medicare Advantage PPO Plan
Humana/ChoiceCare Network PPO
Humana/ChoiceCare+ Network PPO
HumanaNatl POS Open Access
Imagine Health ABC Home
Imagine Health CVS Health
Independent Medical Systems PPO (IMS)
Interplan Health Group
MEDICARE ADVANTAGE : COVENTRY/FIRST HEALTH ADVANTRA
Medicare
MultiPlan PPO
National Preferred Provider Network PPO (NPPN)
Olympus Managed Care (International)
PHCS Healthy Directions
PHCS PPO
Reny Company Workers' Comp
SmartCare PNM Resources
Student Assurance Services Student Accident Plan
TexanPlus Medicare Advantage
Texas Kids First Student Accident Plan
Three Rivers Provider Network
UHC Medicare Chronic Complete
UHC Medicare Complete
UHC Medicare Solutions
UMR
US Family Health Plan
USA Managed Care PPO
United Health Integrated Services
United Healthcare Dual Complete
United Healthcare Medicare Advantage
United Healthcare Nexus ACO
United Healthcare Plan of the River Valley
UnitedHealthOne
UnitedHealthcare Choice
UnitedHealthcare ChoicePlus
UnitedHealthcare Core
UnitedHealthcare Core Plus
UnitedHealthcare EPO
UnitedHealthcare Golden Rule
UnitedHealthcare HMO
UnitedHealthcare Navigate
UnitedHealthcare Navigate Plus
UnitedHealthcare Options PPO
UnitedHealthcare Oxford
UnitedHealthcare POS
UnitedHealthcare PPO
UnitedHealthcare Select / ERS
UnitedHealthcare Student Resources
UnitedHealthcare West
WORKERS' COMP: CareWorks
Workers Comp-Beech Street
Workers' Comp: Coventry / First Health

Insurance plans may change. Please verify your plan is accepted when scheduling an appointment.

Credentials

BOARD CERTIFICATION
American Board of Psychiatry and Neurology, Neurology
MEDICAL SCHOOL
Columbia University College of Physicians and Surgeons, New York, New York | 1960
INTERNSHIP
Harvard University, Cambridge, Massachusetts
RESIDENCY
Neurology, Mount Sinai Medical Center, Miami Beach, Florida
RESEARCH FELLOWSHIP
Duke University Medical Center, Durham, North Carolina
AFFILIATED HOSPITALS
  • Houston Methodist Hospital
CENTER MEMBERSHIP
  • Houston Methodist Neurological Institute
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