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Stephen H. Little, MD

John S. Dunn Chair in Clinical Cardiovascular Research and Education
Houston Methodist DeBakey Cardiology Associates


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Phone: 713-441-1100


6550 Fannin St. Suite 1901
Smith Tower
Houston, TX 77030

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Dr. Little, a cardiologist, is medical director of the Valve Clinic – a multidisciplinary medical clinic at the Houston Methodist DeBakey Heart & Vascular Center focused on the assessment and treatment of complex valvular heart disease.

Dr. Little's recent research activities and peer-reviewed publications have focused on novel use of 3D echocardiography for the quantification of native and prosthetic valve dysfunction as well as imaging guidance for percutaneous structural heart interventions. In collaboration with research scientists and mathematicians, Dr. Little’s research group creates complex heart valve constructs to address an increasingly important clinical need - to improve our understanding of heart valve dysfunction by employing multimodality imaging to better characterize and quantify these complex intra-cardiac flow conditions.

He received his medical degree from McMaster University and completed postgraduate training in internal medicine and cardiology at the University of Western Ontario. Dr. Little completed research fellowships in echocardiography at the University of Ottawa Heart Institute and at Baylor College of Medicine in Houston. He is a fellow of the Royal College of Physicians and Surgeons of Canada, the American College of Cardiology and the American Society of Echocardiography. He is an associate professor of clinical medicine at Weill Cornell Medical College and adjunct associate professor at Rice University in the Department of Bioengineering.

Interests & Special Procedures

Aortic Aneurysms
Cardiovascular Surgery
Myocardial Infarction
Blood Conservation
Mitral Valve Disease
Cardiovascular Disease
Mitral Valve Prolapse
Education & Training

Medical School: McMaster University-Hamilton, Ontario, Canada - 1997
Internship: London Health Sciences Center - London, Canada - 1997
Residency: London Health Sciences Center - London, Canada - 2000
office Locations
6550 Fannin St. Suite 1901
Smith Tower
Houston, TX 77030
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6550 Fannin St. Suite 1401
Valve Clinic - Smith Tower
Houston, TX 77030
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Houston Methodist Hospital
6565 Fannin Street
Houston, TX 77030
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