Physical Sciences-Oncology Center

At the Center for Transport Oncophysics (CTO) at Houston Methodist, our scientists and researchers work diligently to uncover the physics of mass transport within a cancer lesion and mass exchanges between cancer and surrounding host biology. As we understand the mechanisms, our goal is to use that knowledge to develop and improve cancer diagnosis and treatment. The approach we use to study transport oncophysics is to integrate mathematics, engineered transport probes and state-of-the-art imaging.

Our team is focused on two specific cancer types — colorectal cancer (the second leading cause of cancer death in the U.S.) and liver metastasis (the most common site of metastatic disease). One of our major projects includes investigating the physical barriers to the evolution of liver metastasis from colorectal cancer by applying new and innovative carriers in an attempt to breach these barriers.

The center is 1 of 12 supported by the National Cancer Institute (NCI) as part of a collaborative network dedicated to exploring new and innovative approaches to improve understanding and control of cancer.