Showing 1 - 10 of 13 Heart and Blood Diseases

Status: Enrolling

Investigator: Dipan Shah

Study Coordinator: Nirali Patel

Phone: 713.441.2116

This study is designed to evaluate the efficacy of Dotarem enhanced MRI compared to Magnevist and Gadavist enhanced MRI in identifying myocardial infarct. Eighty patients will be recruited for this study. Patients with known CAD and undergoing c ... Read more >

Status: Open Not Enrolling

Investigator: Sherif Nagueh

Study Coordinator: Nirali Patel

Phone: 713.441.2116

Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor Agonist, in Patients With Relapsing-remitting ... Read more >

Status: Open Not Enrolling

Investigator: Orlando Diaz

Study Coordinator:

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The primary objective of this study is to demonstrate effectiveness and safety of the NeuroForm Atlas stent system for use with bare metal embolic coils ... Read more >

Status: Enrolling

Investigator: Mahwash Kassi

Study Coordinator:

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To evaluate the efficacy of eplontersen compared to placebo for 120 weeks in patients with ATTR-CM receiving available standard of care (SoC). For more information, please visit https://www.cardio-ttransform.com. ... Read more >

Status: Open Not Enrolling

Investigator: Neal Kleiman

Study Coordinator: Patricia Brinegar

Phone: 713.441.3506

The primary objective of the study is to evaluate the safety and effectiveness of the Medtronic CoreValve® System (MCS) in a subset of subjects excluded from the U.S. Extreme Risk Pivotal Trial population due to one or more additional co-morbidi ... Read more >

Status: Open Not Enrolling

Investigator: Mahendra Jain

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To evaluate whether long-term treatment with bempedoic acid 180 mg/day versus placebo reduces the risk of major adverse cardiovascular events (MACE) in patients with, or at high risk for, cardiovascular disease (CVD) who are statin intolerant. ... Read more >

Status: Open Not Enrolling

Investigator: Alpesh Shah

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The purpose of this study is to determine whether Fractional flow reserve (FFR, (coronary pressure wire-based index for assessing the ischemic potential of a coronary lesion)-guided percutaneous coronary intervention (PCI) in patients with multi ... Read more >

Status: Enrolling

Investigator: Sherif Nagueh

Study Coordinator: Nirali Patel

Phone: 713.441.2116

Hypertrophic cardiomyopathy (HCM) is the most common monogenic heart disease and the most frequent cause of sudden cardiac death (SCD) in the young. It is characterized by unexplained left ventricular hypertrophy (LVH), diffuse and patchy fibros ... Read more >

Status: Open Not Enrolling

Investigator: Mahwash Kassi

Study Coordinator: Tamer Yahya

Phone: 713.441.3576

This study will evaluate the efficacy and safety of vutrisiran 25 mg administered subcutaneously (SC) once every 3 months (q3M) compared to placebo in patients with ATTR amyloidosis with cardiomyopathy. ... Read more >

Status: Enrolling

Investigator: Vivek Misra

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he primary efficacy objective of the MOST trial is to determine if argatroban (100µg/kg bolus followed by 3µg/kg per minute for 12 hours) or eptifibatide (135µg/kg bolus followed by 0.75µg/kg/min infusion for two hours) results in improved 90-da ... Read more >

Status: Enrolling

Investigator: David Chiu

Study Coordinator:

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A Phase 3 study to examine the safety and effectiveness of the allogeneic, adult stem cell investigational product, MultiStem, in adults who have suffered an acute ischemic stroke in the previous 18-36 hours. ... Read more >

Status: Enrolling

Investigator: Michael Reardon

Study Coordinator: Patricia Brinegar

Phone: 713.441.3506

To evaluate the safety and effectiveness of the Model 400 bovine pericardial stented aortic bioprosthesis in a patient population undergoing surgical aortic valve replacement. The collected data will be used to support regulatory applications in ... Read more >

Status: Open Not Enrolling

Investigator: Neal Kleiman

Study Coordinator: Patricia Brinegar

Phone: 713.441.3506

The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgic ... Read more >