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Showing 1 - 10 of 22 Other
Multicenter, Registry Study of Avance® Nerve Graft Utilization, Evaluations and Outcomes in Peripheral Nerve Injury Repair

Status: Enrolling

Investigator: Warren Ellsworth

Study Coordinator:

Phone:

This is a multicenter registry study to collect utilization, safety, and outcomes data from medical record chart review of nerve reconstruction procedures throughout the body with Avance® Nerve Graft. Addendum 1 (MATCH) establishes a comparat ... Read more >

A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care (ISABELA1)

Status: Enrolling

Investigator: Sandeep Sahay

Study Coordinator: Royanne Holy

Phone: 713.363.7536

The main purpose of this study is to see how GLPG1690 works together with your current standard treatment on your lung function and IPF disease in general. The study will also investigate how well GLPG1690 is tolerated (for example if you get an ... Read more >

A Comparison of Quality of Life and Patient Satisfaction Between Two Headache Populations

Status: Open Not Enrolling

Investigator: Ericka Greene

Study Coordinator:

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The purpose of this study is to evaluate patient-reported outcomes (PROs) and quality of life (QoL) in two general neurology clinical populations – private pay patients at Houston Methodist Neurological institute (HMNI) and charity care patients ... Read more >

A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

Status: Enrolling

Investigator: Bincy Abraham

Study Coordinator: Alejandro De La Torre

Phone: 713.441.6396

This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label. ... Read more >

A Multicenter, Registry Study of Avance® Nerve Graft Utilization, Evaluations and Outcomes in Peripheral Nerve Injury Repair

Status: Enrolling

Investigator: Aldona Spiegel

Study Coordinator:

Phone:

This is a multicenter registry study to collect utilization, safety, and outcomes data from medical record chart review of nerve reconstruction procedures throughout the body with Avance® Nerve Graft. Addendum 1 (MATCH) establishes a comparat ... Read more >

A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

Status: Enrolling

Investigator: Monisha Singh

Study Coordinator: Caroline Fitzgerald

Phone: 713.441.3250

NGM120 is an experimental drug made by NGM Biopharmaceuticals, Inc. NGM120, given as an injection, is designed to block a factor that is associated with cancer. NGM120 has shown in various animal models of cancer to reduce tumor size and improve ... Read more >

A Prospective, Randomized, Multi-center, Single-Blinded, Placebo-Controlled, 3-Arm Clinical Study to Assess the Efficacy and Safety of Vibrant Capsule, for the Treatment of Chronic Idiopathic Constipation

Status: Enrolling

Investigator: Eamonn Quigley

Study Coordinator: Hernetta Mitchell

Phone: 281.485.3434

The study is a prospective, randomized, multicenter, adaptive design, single blinded, placebo-controlled study, to evaluate the efficacy and safety of Vibrant Capsule vs. placebo in relieving constipation in subjects with Chronic Idiopathic Cons ... Read more >

A Registry for Patients Taking Uptravi (SPHERE)

Status: Open Not Enrolling

Investigator: Zeenat Safdar

Study Coordinator: Jennifer Lee

Phone: 713.363.7537

This is a US multi-center, prospective, real world, observational drug registry enrolling patients actively treated with Uptravi. Participating patients will be followed prospectively for a maximum of 18 months from the date of enrollment into t ... Read more >

A011-09 PULSAR A Phase 2 Study of Sotatercept for the Treatment of PAH

Status: Open Not Enrolling

Investigator: Zeenat Safdar

Study Coordinator: Royanne Holy

Phone: 713.363.7536

Study A011-09 is a Phase 2, double-blind, randomized, placebo-controlled, multicenter, parallel-group study to determine the efficacy and safety of sotatercept (ACE-011) plus standard of care (SOC) versus placebo plus SOC in adults with pulmonar ... Read more >

ADAPT - A Patient Registry of the Real-world Use of Orenitram®

Status: Enrolling

Investigator: Sandeep Sahay

Study Coordinator: Jennifer Lee

Phone: 713.363.7537

This prospective, observational, multicenter, patient registry will follow patients who are receiving treatment with Orenitram for the treatment of PAH for up to 78 weeks from Orenitram initiation ... Read more >

An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis (OPAL)

Status: Enrolling

Investigator: Bincy Abraham

Study Coordinator:

Phone:

The purpose of this study is to compare the incidence of lymphoma in adult participants with moderate-to-severe ulcerative colitis who are treated with Simponi versus those treated with thiopurines. ... Read more >

Corrona Inflammatory Bowel Disease (IBD) Registry

Status: Enrolling

Investigator: Bincy Abraham

Study Coordinator: Caroline Perry

Phone: 346.238.0307

This prospective, non-interventional research registry is designed to study the comparative effectiveness and comparative safety of approved treatments for IBD in a cohort of patients cared for by gastroenterologists across North America. Second ... Read more >

GORE® TAG® Thoracic Branch Endoprosthesis

Status: Enrolling

Investigator: Marvin Atkins

Study Coordinator: Kim Donlon

Phone: 713.441.9394

This study is a prospective, multicenter, non-randomized single-arm study to assess the feasibility of the treatment of DeBakey Type I/II aortic dissections with the GORE® TAG® Thoracic Branch Endoprosthesis system. ... Read more >

Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry (IPF/ILD-PRO)

Status: Enrolling

Investigator: Zeenat Safdar

Study Coordinator: Jennifer Lee

Phone: 713.363.7537

This registry will collect data on the strategies used to achieve a diagnosis of Idiopathic Pulmonary Fibrosis (IPF) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype (ILD) and the treatment and management efforts applie ... Read more >

Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso (BREEZE)

Status: Enrolling

Investigator: Sandeep Sahay

Study Coordinator: Jennifer Lee

Phone: 713.363.7537

United Therapeutics Corporation (UTC) is developing a combination drug-device product which is comprised of a dry powder formulation of Treprostinil Inhalation Powder (TreT) and a small, portable, dry powder inhaler. In this Phase 1b safety and ... Read more >

PIANO

Status: Enrolling

Investigator: Bincy Abraham

Study Coordinator: Caroline Perry

Phone: 346.238.0307

A Multicenter National Prospective Study of Pregnancy and Neonatal Outcomes in Women with Inflammatory Bowel Disease study is being conducted at the University of California San Francisco and 30 other sites around the United States who are part ... Read more >

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension standard of care or PAH-specific background therapy in subjects with World Health Organization Group 1 PAH

Status: Enrolling

Investigator: Zeenat Safdar

Study Coordinator: Royanne Holy

Phone: 713.363.7536

Study ROR-PH-301 is a multicenter, randomized, double-blind, placebo-controlled study. Subjects who meet entry criteria will be randomly allocated 1:1 to receive ralinepag or placebo, in addition to their standard of care or PAH-specific backgro ... Read more >

Study ROR-PH-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag

Status: Enrolling

Investigator: Zeenat Safdar

Study Coordinator: Royanne Holy

Phone: 713.363.7536

Study ROR-PH-303 is a multicenter, open-label extension (OLE) study for subjects with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag and who qualify for entry based upon participation in the prior study. S ... Read more >

Supraspinal Targets in Voiding Dysfunction

Status: Enrolling

Investigator: Rose Khavari

Study Coordinator:

Phone:

Difficulty in bladder emptying (Voiding dysfunction,VD) is a costly urinary condition that leads to urinary tract infections/stones, sepsis, bladder loss, and permanent kidney damage. VD can be present in patients with or without neurologic/brai ... Read more >

The MARE Study

Status: Open Not Enrolling

Investigator: Neal Kleiman

Study Coordinator:

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The purpose of this study is to determine the incidence and predictors of high degree or complete atrioventricular block (AVB) (paroxysmal or persistent) in patients with new-onset persistent left bundle branch block (NOP-LBBB) following transca ... Read more >

The MENDSII Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure (MENDSII)

Status: Open Not Enrolling

Investigator: Joshua Swan

Study Coordinator: Joy Nolte Fong

Phone: 713.441.6314

Ventilated ICU patients frequently have sepsis and the majority have delirium, a form of brain dysfunction that is an independent predictor of increased risk of dying, length of stay, costs, and prolonged cognitive impairment in survivors. Unive ... Read more >

X-linked Hypophosphatemia Disease Monitoring Program (XLH-DMP)

Status: Enrolling

Investigator: Dale Hamilton

Study Coordinator: Melissa Whipple

Phone: 713.441.3247

The XLH-DMP is a global, prospective, multicenter, longitudinal, long-term outcomes program for subjects on or off any treatment designed to characterize XLH disease presentation and progression, assess long-term safety and effectiveness of buro ... Read more >