Showing 1 - 7 of 7 Amyotrophic Lateral Sclerosis (ALS)
Genomic Translation for ALS Clinical Care

Status: Enrolling

Investigator: Stanley Appel

Study Coordinator: Sharon Halton

Phone: 713.441.3420

The purpose of the this study to look for abnormal genes and gene expression profiles that help determine why a person develops amyotrophic lateral sclerosis (ALS) and related motor neuron diseases (MND) and why their symptoms present and progre ... Read more >

HEALEY ALS Platform Trial

Status: Enrolling

Investigator: Stanley Appel

Study Coordinator:

Phone:

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. ... Read more >

HEALEY ALS Platform Trial - Regimen A Zilucoplan

Status: Enrolling

Investigator: Stanley Appel

Study Coordinator:

Phone:

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. Regimen A will evaluate the safety and efficacy of a single study ... Read more >

HEALEY ALS Platform Trial - Regimen B Verdiperstat

Status: Enrolling

Investigator: Stanley Appel

Study Coordinator:

Phone:

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. Regimen B will evaluate the safety and efficacy of a single study ... Read more >

HEALEY ALS Platform Trial - Regimen C CNM-Au8

Status: Enrolling

Investigator: Stanley Appel

Study Coordinator: Bing Liao

Phone: 713.363.7310

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. Regimen C will evaluate the safety and efficacy of a single study ... Read more >

Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)

Status: Enrolling

Investigator: Sheetal Shroff

Study Coordinator:

Phone:

REFINE-ALS is a prospective, observational, longitudinal, multicenter study designed to identify biomarkers to serve as quantifiable biological non-clinical measures of Edaravone effects in ALS. Epigenetic and protein biomarkers will also be inv ... Read more >

T-regulatory Cells in ALS (Tregs in ALS)

Status: Active

Investigator: Jason Thonhoff

Study Coordinator: Patricia Mendoza

Phone: 713.441.5855

This study is a randomized, placebo-controlled, phase 2a trial to study the biological activity, safety, and tolerability of regulatory T Lymphocytes (Tregs) taken and expanded outside of the body and returned back to the same person whose Treg ... Read more >