Our Research


At Houston Methodist, fostering innovations with the potential for clinical application is at the very heart of what we do. Together with physicians, researchers at Houston Methodist are committed to streamlining the process of 'translating' laboratory research into treatments and cures for our patients. Our commitment to the full translational cycle from discovery to cure is how we deliver on our mission of leading medicine.

Starting from the earliest phase of discovery in a lab to testing new drugs or therapies in clinical trials, our interdisciplinary research teams are focusing on several research areas with a central objective of developing treatments with ready applicability to human disease. This emphasis is being taken even further with the 440,000-square-foot Houston Methodist Research Institute building that is connected to the Houston Methodist Hospital, and is enabling physicians and researchers to work together on rapidly translating discoveries into new diagnostics, therapies and treatments. 

We also support a global research collaboration network of teams with expertise in nontraditional platform technologies and programs, providing the administrative support, staff and facilities that are needed for translational research. 


Researchers at Houston Methodist and Weill Cornell have developed a portable, wearable system for transcranial magnetic stimulation to treat major depression. The device, a helmet cap with a handheld controller, can be used at home with a prescribed treatment protocol. Learn more. 


This trial will evaluate the safety and effectiveness of the MitraClip device for the treatment of moderate-to-severe or severe mitral valve leak, also called functional mitral regurgitation, in patients with heart failure. Learn more.

Meet Joseph Masdeu, MD, PhD

Dr. Joseph Masdeu, MD, PhD, the Graham Family Distinguished Chair for Neurological Sciences is on a mission to understand the neurobiology of Alzheimer’s disease and other neurodegenerative disorders though approaches like neuroimaging.
Learn more.

Magnetic nanoparticles could stop blood clot-caused strokeS

By loading magnetic nanoparticles with drugs and then biochemically camouflaging them, we can offer a technique that destroys blood clots 100 to 1,000 times faster than a traditional method. Learn more.