Our Research


At Houston Methodist, fostering innovations with the potential for clinical application is at the very heart of what we do. Our interdisciplinary teams of clinicians and researchers are committed to streamlining the process of translating discoveries into treatments and cures for our patients. 

Learn more about how we are delivering on our commitment to leading medicine from the earliest phase of discovery in a lab to the testing new drugs or therapies in clinical trials.

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A Houston Methodist team led by Mauro Ferrari, PhD and Jenny Chang, MD has received funding from the U.S. Department of Defense to complete preclinical efficacy studies and a future clinical trial testing a breast cancer precision drug. Learn more.


Blood Test May Identify Cancer Patients at Risk for Brain Metastasis
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Houston Methodist researchers led by Dario Marchetti, PhD, have developed a blood test that can identify circulating tumor cells to predict breast cancer patients at risk for developing brain metastasis. Learn more.


RNA Therapy Reverses Effects of Aging in Progeria Cells
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Houston Methodist scientists led by John Cooke, MD, PhD used telomerase mRNA technology to reverse senescence, rejuvenating aging human cells. Learn more.

Protein Protecting T-cells Aids in Destruction of Liver Immune Cells
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A Houston Methodist research team led by Xian Li, MD, PhD, identified the surface protein OX40 as a mediator of liver inflammation and disease. Learn more.

Latest News
Thursday, March 22, 2018 Researchers identify compound that prevents breast cancer stem cells from activating in the brain
Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain.     Researchers at Houston Methodist culled through thousands of existing drugs to see if they could id...
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Wednesday, March 7, 2018 Houston Methodist Researcher Makes Bold Move by Releasing Nanotech ‘Recipe’
In a rare move, a Houston Methodist researcher is sharing his recipe for a new, more affordable way to make nanoparticles. This will empower any laboratory in the world to easily create similar nanoparticles and could lead to a whole new way of delivering biotherapeutic drugs and do it more quickly....
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