Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Clinical Innovations and Outcomes Program

Clinical Innovation and Outcomes Program

The Clinical Innovations and Outcomes Program is a multidisciplinary program designed to foster the development of Principal Investigator-initiated clinical trials, participate and recruit for industry sponsored clinical trials and report on the outcomes of cardiovascular procedures. This program is integrated with the clinical research arm of The Methodist Hospital Research Institute (TMHRI) and provides administrative and biostatistical support for investigators to carry out clinical research in cardiovascular disease. The program offers a Research Fellowship and provides residents and students with both training and faculty mentoring in Clinical Research. The focus areas are Cardiovascular Imaging and Simulation, Minimally Invasive and Robotic Cardiovascular Surgery, Aortic Aneurysmal Disease, Dialysis Access, Lower Extremity Arterial and Venous Interventions and Vascular Progenitor Cell Therapy. Innovative collaborations occur with the Oil and Gas and Biotechnology industries through the annual Pumps and Pipes symposium that brings biomedical researchers together with oil and gas scientists to allow the free exchange of ideas and development of joint projects. The program also provides opportunities for MBA students to study Health Care Finances and the Business of Medicine.

Current funding

NSF - CPS (0932272)"Image Guided Robot-Assisted Medical Interventions"
NHLBI (U01 HL077221) "Claudication: Exercise vs. Endoluminal Revascularization (CLEVER)

Publications:

Aorta

Younes HK, Harris PW, Bismuth J, Charlton-Ouw K, Peden EK, Lumsden AB, Davies MG. Thoracic Endovascular Aortic Repair for Type B Aortic Dissection. Ann Vasc Surg 2010: 24(1):39-43.

Younes HK, Davies MG, Bismuth J, Naoum JJ, Peden EK, Reardon MJ, Lumsden AB. Hybrid thoracic endovascular aortic repair (TEVAR): Pushing the envelope? J Vasc Surg 2010; 51(1): 259-266.

Karmonik C, Bismuth J, Davies MG, Younes HK, Lumsden AB. An Image Processing Algorithm for the In-vivo Quantification and visualization of septum motion in type III B - aortic dissections with cine magnetic resonance imaging. Conf Proc IEEE Eng Med Biol Soc 2009; 1: 4391-4.

Bakken AM, Palchik E, Saad WE, Waldman DL, Davies MG. Longterm outcomes of endoluminal therapy for ostial disease of the major branches of the aortic arch. Ann Vasc Surg 2008; 22: 388-394.

Karmonik C, Bismuth JX, Davies MG, Lumsden AB. Computational Hemodynamics in the Human Aorta: a Computational Fluid Dynamics Study of Three Cases with Patient-Specific Geometries and Inflow Rates. Technol Health Care 2008: 16(5): 343-354.

Renal

Davies MG, Bismuth J, Saad WE, Naoum JJ, Peden EK, Lumsden AB. Renal parenchymal preservation after percutaneous renal angioplasty and stenting. J Vasc Surg 2010: 51(5):1222-9.

Davies MG, Bismuth J, Saad WE, Naoum JJ, Peden EK, Lumsden AB. Impact of Metabolic Syndrome on the Outcomes of Percutaneous Renal Angioplasty and Stenting. J Vasc Surg 2010: 51:926-32.

Protack CD, Bakken AM, Saad WE, Davies MG. Renal artery interventions during EVAR: a greater potential of subsequent failure? J Vasc Intervent Radiol 2010: 21(4): 459-64.

Davies MG, Saad WE, Bismuth J, Peden EK, Naoum JJ, Lumsden AB. Outcomes Of Endoluminal Re-Intervention For Restenosis After Percutaneous Renal Angioplasty And Stenting. J Vasc Surg 2009: 49:946-52.

Davies MG, Saad WE, Bismuth J, Peden EK, Naoum JJ, Lumsden AB. Endovascular Revascularization Of Renal Artery Stenosis In The Solitary Functioning Kidney. J Vasc Surg 2009: 49:953-60.

Davies MG, Saad WE, Peden EK, Naoum JJ, Mohiuddin IT, Lumsden AB. The long-term outcomes of Percutaneous Therapy for Renal Artery Fibromuscular Dysplasia. J Vasc Surg 2008: 48; 865-871.

Davies MG, Saad WE, Peden EK, Mohiuddin IT, Naoum JJ, Lumsden AB. Implications of acute renal injury following percutaneous renal artery intervention. Ann Vasc Surg 2008: 22(6):783-9.

Dialysis Access

Kaiser CL, Anaya-Ayala JE, Ismail N, Davies MG, Peden EK. Unrecognized basilic vein variation leading to complication during basilic vein transposition arteriovenous fistula creation: Case report and implications for access planning. Eur J Vasc Endovasc Surg 2010 39(5):627-9.

Lower Extremity

Davies MG, Bismuth J, Saad WE, Naoum JJ, Peden EK, Lumsden AB. Implications of in situ thrombosis and distal embolization during superficial femoral artery endoluminal intervention. Ann Vasc Surg 2010; 24(1):14-22.

Vykoukal D, Davies MG. Stent Grafting in the Superficial Femoral Artery. Ital J Vasc Endo Surg 2010: 17:23-30.

Davies MG, Bismuth J, Saad WE, Naoum JJ, Peden EK, Lumsden AB. Outcomes of Interventions for Recurrent Disease after Endoluminal Intervention for Superficial Femoral Artery Disease. J Vasc Surg 2010: 52:331-9.

Bakken AM, Protack CD, Saad WE, Rhodes JR, Hart JP, Waldman DL, Davies MG. Impact of Chronic Kidney Disease on Outcomes of Superficial Femoral Artery Endoluminal Interventions Ann Vasc Surg 2009: 23(5):560-8.

Lumsden AB, Davies MG, Peden EK. Medical and Endovascular Management of Critical Limb Ischemia. J Endovasc Ther 2009;16(supplII): II-31-II-62.

Bakken AM, Saad WEA, Davies MG. Cryo balloon angioplasty broadens the role of primary angioplasty and reduces adjuvant stenting in complex superficial femoral artery (TASC C and D) lesion. J Am Coll Surg 2008; 206(3):524-32.

Davies MG, Saad WE, Peden EK, Mohiuddin IT, Naoum JJ, Lumsden AB. Percutaneous superficial femoral artery interventions for claudication--does runoff matter? Ann Vasc Surg 2008; 22(6):790-8.

Davies MG, Saad WE, Peden EK, Mohiuddin IT, Naoum JJ, Lumsden AB. Impact of runoff on superficial femoral artery endoluminal interventions for Rest Pain and Tissue Loss. J Vasc Surg 2008; 48(3):619-25.

Carotid

Protack CD, Bakken AM, Xu J, Saad WE, Lumsden AB, Davies MG. Metabolic Syndrome: a predictor of adverse events after Carotid Revascularization J Vasc Surg 2009: 49:1172-80.

Garami ZP, Bismuth J, Charlton-Ouw K, Davies MG, Peden EK, Lumsden AB. The feasability of imultaneous pre- and post-filter transcranial doppler monitoring during carotid artery stenting J Vasc Surg 2009; 49(2): 340-345.

General

SVS Task Force on Comparative Effectiveness (Stoner M, Davies MG, Forbes T, Meissner M, LoGerfo F). Comparative Effectiveness Research in Vascular Interventions. J Vasc Surg 2009; 49(6):1592-1593.