Clinical Trials

    CREST-2

    Investigator: David Chiu

    Study Coordinator:

    Status: Enrolling

    ClinicalTrials.gov Number: NCT02089217

    Phone:

    Protocol Number: Pro00012292

    Description


    Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed.