Clinical Trials

    Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/?HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

    Investigator: Kai Sun

    Study Coordinator: Milan Sheth

    Status: Open Not Enrolling

    ClinicalTrials.gov Number: NCT06797635

    Phone: 713.790.3311

    Protocol Number: PRO00039797

    Description


    Researchers are looking for new ways to treat triple-negative breast cancer (TNBC) and hormone receptor (HR) low positive/human epidermal growth factor receptor-2 (HER2) negative breast cancer. The main goals of this study are to learn: About the safety of the study treatments and if people tolerate them If people who receive patritumab deruxtecan, pembrolizumab, and chemotherapy before surgery have fewer cancer cells removed during surgery compared to those who receive only pembrolizumab (pembro) and chemotherapy.