Clinical Trials

    A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/?Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/?HER2-negative Breast Cancer

    Investigator: Kai Sun

    Study Coordinator: Jawairia Jawed

    Status: Open Not Enrolling

    ClinicalTrials.gov Number: NCT06112379

    Phone: 346.356.3603

    Protocol Number: PRO00038124

    Description


    This is a Phase III, 2-arm, randomised, open-label, multicentre, global study assessing the efficacy and safety of neoadjuvant Dato-DXd plus durvalumab followed by adjuvant durvalumab with or without chemotherapy compared with neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab with or without chemotherapy in participants with previously untreated TNBC or hormone receptor-low/HER2-negative breast cancer.