Clinical Trials

    A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

    Investigator: Hanh Mai

    Study Coordinator: Jawairia Jawed

    Status: Open Not Enrolling

    ClinicalTrials.gov Number: NCT05629585

    Phone: 346.356.3603

    Protocol Number: PRO00037085

    Description


    This is a Phase III, randomized, open-label, 3-arm, multicenter, international study assessing the efficacy and safety of Dato-DXd with or without durvalumab compared with ICT in participants with stage I to III TNBC with residual invasive disease in the breast and/or axillary lymph nodes at surgical resection following neoadjuvant systemic therapy.