Status: Enrolling
Investigator: Jenny Chang
Study Coordinator:
Phone:
The purpose of this research study is to test the safety and effectiveness of docetaxel chemotherapy and pembrolizumab plus adenoviral-mediated interleukin-12 (ADV/IL-12) gene therapy in patients with anthracycline-refractory, triple negative br ... Read more >
Status: Open Not Enrolling
Investigator: Jenny Chang
Study Coordinator:
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This is a pilot study is evaluating the effect of hydroxytyrosol, a component of Olive oil, on mammographic density in women at high risk of breast through assessing whether mammographic density is reduced in women at high risk of breast cancer ... Read more >
Status: Open Not Enrolling
Investigator: Jenny Chang
Study Coordinator:
Phone:
Hormone receptor positive breast cancer HRBC is the most common cause of BC-related death. HRBC is characterized by a non-immunogenic microenvironment and consequently, modest responses have been observed with immune checkpoint blockade ICB alon ... Read more >
Status: Open Not Enrolling
Investigator: Jenny Chang
Study Coordinator:
Phone:
The purpose of this exploratory biomarker study is to further our understanding of the role of cancer stem cells (CSCs) and other biomarkers in the progression of COPD to lung cancer by examining the CSC population and other related biomarkers, ... Read more >
Status: Enrolling
Investigator: Jenny Chang
Study Coordinator: Ezinne Onuoha
Phone: 832.874.9052
The study will investigate if a one month drug holiday from the CDK4/6 inhibitor drug, abemaciclib, will restore the body's sensitivity to the drug and make the subsequent treatment of abemaciclib plus fulvestrant more effective. ... Read more >
Status: Open Not Enrolling
Investigator: Jenny Chang
Study Coordinator: Toniva Boone
Phone: 713.441.0686
The purpose of this exploratory biomarker study is to further our understanding of the role of CSCs in lung cancer metastasis by examining the CSC population in metastatic tissue. ... Read more >
Status: Enrolling
Investigator: Jenny Chang
Study Coordinator:
Phone:
This is a Phase I/Ib study testing the safety and preliminary efficacy of olaparib and vorinostat when used together in participants with relapsed/refractory and or metastatic breast cancer. Cancer cells grow in an uncontrolled manner and this c ... Read more >
Status: Enrolling
Investigator: Jenny Chang
Study Coordinator:
Phone:
The purpose of this research study is to test the safety and effectiveness of using durvalumab with trastuzumab and pertuzumab in participants with human epidermal growth factor receptor 2 (HER2)-enriched breast cancer. ... Read more >
Status: Open Not Enrolling
Investigator: Jenny Chang
Study Coordinator:
Phone:
This is a Phase II trial to determine the efficacy and safety of stereotactic body radiation therapy (SBRT) and in situ oncolytic virus therapy used as a window of opportunity treatment before pembrolizumab in patients with metastatic triple neg ... Read more >
Status: Enrolling
Investigator: Jenny Chang
Study Coordinator:
Phone:
This is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single agent and in combination with pembrolizumab in participants with a ... Read more >
