Showing 1 - 8 of 8 Digestive System Diseases

Status: Open Not Enrolling

Investigator: Maen Abdelrahim

Study Coordinator: Daniel (cancer) Le (cancer)

Phone: 346.238.5655

A Phase 2, multicenter, open-label, 2-stage study to assess the safety, tolerability, and efficacy of XERMELO in combination with first-line (1L) therapy (cisplatin [cis] plus gemcitabine [gem]) in patients with unresectable, locally advanced, r ... Read more >

Status: Enrolling

Investigator: Maen Abdelrahim

Study Coordinator: Juan Morales Viera

Phone: 786.803.2333

The purpose of this study is to evaluate the efficacy of zolbetuximab plus capecitabine and oxaliplatin (CAPOX) compared with placebo plus CAPOX (as first-line treatment) as measured by Progression Free Survival (PFS). This study will also ev ... Read more >

Status: Open Not Enrolling

Investigator: Maen Abdelrahim

Study Coordinator:

Phone:

The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall survival and assess the safety and tolerability of the combination treatment. This study will also ... Read more >

Status: Enrolling

Investigator: Maen Abdelrahim

Study Coordinator: Jose Cruz

Phone: 713.441.4457

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement. < ... Read more >

Status: Open Not Enrolling

Investigator: Mahendra Jain

Study Coordinator: Bela Jain

Phone: 281.485.3434

To evaluate whether selonsertib (SEL) can slow the decline in kidney function, reduce the risk of kidney failure, or reduce the risk of death due to kidney disease in subjects with diabetic kidney disease (DKD) ... Read more >

Status: Open Not Enrolling

Investigator: Mahendra Jain

Study Coordinator: Bela Jain

Phone: 281.485.3434

In patients with diabetes and high triglycerides, subjects will be given pemafibrate to help reduce triglycerides level and cardiovascular outcomes. ... Read more >

Status: Enrolling

Investigator: Kirk Heyne

Study Coordinator: Caroline Fitzgerald

Phone: 713.441.3250

The purpose of this study is to investigate nivolumab combined with Debio 1143. The study will focus on subjects with specific solid tumors for whom tumors were previously treated with anti-PD-1/PD-L1 therapy as a single therapy (or when used wi ... Read more >

Status: Enrolling

Investigator: Mark Sultenfuss

Study Coordinator:

Phone:

This research registry studies Yttrium Y 90 resin microspheres in collecting data from patients with liver cancer not capable of being removed by surgery (unresectable) for the radiation-emitting Selective Internal Radiation-Spheres (SIR-spheres ... Read more >