Clinical Trials

    Showing 1 - 7 of 7 Heart Defects

    AC-058B201 Echocardiographic Ancillary Study

    Status: Open Not Enrolling

    Investigator: Sherif Nagueh

    Study Coordinator: Nirali Patel

    Phone: 713.441.2116

    Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor Agonist, in Patients With Relapsing-remitting Mult... Read more >

    Amplatzer Amulet LAAO vs. NOAC (CATALYST)

    Status: Enrolling

    Investigator: Miguel Valderrabano

    Study Coordinator: Aneesch Martin

    Phone: 713.441.6548

    Brief Summary: The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term N... Read more >

    Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

    Status: Enrolling

    Investigator: Neal Kleiman

    Study Coordinator: Deena Victor

    Phone: 713.441.4536

    Brief Summary: To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation (DMR) who have been determined to be at prohibitive risk for mitral valve surgery by ... Read more >

    MitraClip REPAIR MR Study

    Status: Enrolling

    Investigator: Sachin Goel

    Study Coordinator: Tia McGaughy

    Phone: 346.238.4576

    Brief Summary: The objective of this randomized controlled trial (RCT) is to compare the clinical outcome of MitraClip™ device versus surgical repair in patients with severe primary MR who are at moderate surgical risk and whose mitral valve has bee... Read more >

    Transcatheter Mitral Valve Replacement With the Medtronic Intrepid TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)

    Status: Enrolling

    Investigator: Neal Kleiman

    Study Coordinator: Tia McGaughy

    Phone: 346.238.4576

    Brief Summary: Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device. Inclusion Criteria: Moderate to severe or severe symptomatic mitral regurgitation Local sit... Read more >

    TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV) (TRICAV)

    Status: Enrolling

    Investigator: Sachin Goel

    Study Coordinator: Yejide Oyewole

    Phone: 346.238.2294

    This is a prospective multicenter clinical investigation designed to evaluate the safety and effectiveness of the TricValve® Transcatheter Bicaval Valve System for improving outcomes in symptomatic subjects with severe TR deemed by the local Heart Te... Read more >

    TRILUMINATE Pivotal Trial

    Status: Open Not Enrolling

    Investigator: Stephen Little

    Study Coordinator: Padmaja Naik

    Phone: 713.441.7386

    Brief Summary: The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or great... Read more >