Status: Open Not Enrolling
Investigator: Sherif Nagueh
Study Coordinator: Nirali Patel
Phone: 713.441.2116
Multicenter, Randomized, Double-blind, Parallel-group Extension to Study AC-058B201 to Investigate the Long-term Safety, Tolerability, and Efficacy of Three Doses of ACT-128800, an Oral S1P1 Receptor Agonist, in Patients With Relapsing-remitting ... Read more >
Status: Open Not Enrolling
Investigator: Michael Reardon
Study Coordinator: Iris Alanis
Phone: 713.441.6548
Brief Summary: Prospective, single-arm, multicenter study to evaluate the safety and performance of the AltaValve for the treatment of moderate to severe or severe mitral valve regurgitation in subjects who are considered high risk for mortalit ... Read more >
Status: Enrolling
Investigator: Miguel Valderrabano
Study Coordinator: Aneesch Martin
Phone: 713.441.6548
Brief Summary: The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-t ... Read more >
Status: Open Not Enrolling
Investigator: Sachin Goel
Study Coordinator: Tia McGaughy
Phone: 346.238.4576
Brief Summary: Study to evaluate the feasibility, safety and performance of the HighLife trans-septal Transcatheter Mitral Valve in patients with moderate-severe and severe mitral regurgitation who are at high risk for surgical treatment. In ... Read more >
Status: Enrolling
Investigator: Neal Kleiman
Study Coordinator: Deena Victor
Phone: 713.441.4536
Brief Summary: To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation (DMR) who have been determined to be at prohibitive risk for mitral valve surger ... Read more >
Status: Enrolling
Investigator: Sachin Goel
Study Coordinator: Tia McGaughy
Phone: 346.238.4576
Brief Summary: The objective of this randomized controlled trial (RCT) is to compare the clinical outcome of MitraClip™ device versus surgical repair in patients with severe primary MR who are at moderate surgical risk and whose mitral valve ha ... Read more >
Status: Enrolling
Investigator: Neal Kleiman
Study Coordinator: Tia McGaughy
Phone: 346.238.4576
Brief Summary: Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device. Inclusion Criteria: Moderate to severe or severe symptomatic mitral regurgitation Loca ... Read more >
Status: Open Not Enrolling
Investigator: Stephen Little
Study Coordinator: Iris Alanis
Phone: 713.441.6548
Brief Summary: The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or ... Read more >