Showing 1 - 10 of 10 Blood and Lymph Conditions

Status: Open Not Enrolling

Investigator: Maen Abdelrahim

Study Coordinator: Sharell Cornett-Risher

Phone: 713.441.3250

This is an open-label, dose-escalation/dose-expansion study of INCB057643 in subjects with advanced malignancies. Part 1 will determine the maximum tolerated dose of INCB057643 and/or a tolerated dose that demonstrates sufficient pharmacologic a ... Read more >

Status: Enrolling

Investigator: Sai ravi kiran Pingali

Study Coordinator: Sharell Cornett-Risher

Phone: 713.441.3250

This study will evaluate the safety, efficacy, and pharmacokinetics of atezolizumab alone and in combination with various immunomodulatory agents in patients with relapsed/refractory multiple myeloma or patients with myeloma who have measureabl ... Read more >

Status: Open Not Enrolling

Investigator: Monisha Singh

Study Coordinator: Ashley Towne

Phone: 346.238.2006

This study is an open-label, multicenter, phase 1, dose escalation study of TAK-659 in adult patients with advanced solid tumor and lymphoma malignancies. This study will be the first to administer TAK-659 to humans. The patient population durin ... Read more >

Status: Enrolling

Investigator: Brian Bruckner

Study Coordinator: Deborah Barr

Phone: 713.441.3916

This study is evaluating the effectiveness of PleuraFlow System Active Clearance Technology (ACT) in the management of blood evacuation. The Pleuraflow System ACT is a guided wire with a distal loop that rests at the end of a chest tube. The sys ... Read more >

Status: Enrolling

Investigator: Maen Abdelrahim

Study Coordinator: Ashley Towne

Phone: 346.238.2006

Open label, multi-center dose escalation and dose expansion study designed to evaluate safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor effects of ALRN-6924 in patients with advanced solid tumors or lymphomas with wild-typ ... Read more >

Status: Enrolling

Investigator: Jasleen Randhawa

Study Coordinator: Ashley Towne

Phone: 346.238.2006

Multicenter, randomized, open-label, crossover PK study of ASTX727 versus IV decitabine. Adult subjects who are candidates to receive IV decitabine will be randomized 1:1 to receive the ASTX727 tablet Daily×5 in Cycle 1 followed by IV decitabine ... Read more >

Status: Open Not Enrolling

Investigator: Sai ravi kiran Pingali

Study Coordinator: Erick Villarreal-Williams

Phone: 713.441.9775

A clinical research study to find out if it is safe to stop the drug nilotinib (Tasigna) in chronic myeloid leukemia (CML) patients. Patients who started treatment with imatinib (Gleevec) when they were first diagnosed with CML, then switched to ... Read more >

Status: Open Not Enrolling

Investigator: Alpesh Shah

Study Coordinator: Patricia Brinegar

Phone: 713.441.3506

This is a prospective, multi-center, non-randomized, single arm clinical trial that will be conducted at up to 40 sites in the United States and OUS. A minimum of 40% of total patients will be enrolled in the US. This study will enroll patient ... Read more >

Status: Enrolling

Investigator: Alan Lumsden

Study Coordinator: Kim Donlon

Phone: 713.441.9394

This prospective, multicenter, single-arm clinical study will further evaluate the safety and effectiveness of Cook's permanent and retrievable inferior vena cava (IVC) filters (specifically, the Günther Tulip® Vena Cava Filter and Cook Celect® ... Read more >

Status: Active

Investigator: Swaminathan Iyer

Study Coordinator: Sharell Cornett-Risher

Phone: 713.441.3250

This is a Phase 2, open-label, multicenter trial designed to evaluate the efficacy and safety of CUDC-907 monotherapy and R-907 (rituximab in combination with CUDC-907) in subjects 18 years and older with Relapsed/Refractory (RR) MYC-altered Dif ... Read more >