Showing 1 - 7 of 7 Coronary Artery Disease
A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen

Status: Open Not Enrolling

Investigator: Kershaw Patel

Study Coordinator: Iris Alanis

Phone: 713.441.6548

A Phase 2 trial to evaluate the blood pressure-lowering effect of lorundrostat (an aldosterone synthase inhibitor), administered on a background of a standardized anti-hypertensive (AHT) medication regimen, in subjects with uncontrolled and/or t ... Read more >

CoreValve® Expanded

Status: Open Not Enrolling

Investigator: Neal Kleiman

Study Coordinator: Deena Victor

Phone: 713.441.4536

The primary objective of the study is to evaluate the safety and effectiveness of the Medtronic CoreValve® System (MCS) in a subset of subjects excluded from the U.S. Extreme Risk Pivotal Trial population due to one or more additional co-morbidi ... Read more >

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II (COSIRA-II)

Status: Enrolling

Investigator: Alpesh Shah

Study Coordinator: Padmaja Naik

Phone: 713.441.7386

To demonstrate the safety and effectiveness of the Reducer system for treatment of patients with refractory angina pectoris treated with maximally tolerated guideline-directed medical therapy who demonstrate objective evidence of reversible myoc ... Read more >

FAME 3

Status: Open Not Enrolling

Investigator: Alpesh Shah

Study Coordinator: Iris Alanis

Phone: 713.441.6548

The purpose of this study is to determine whether Fractional flow reserve (FFR, (coronary pressure wire-based index for assessing the ischemic potential of a coronary lesion)-guided percutaneous coronary intervention (PCI) in patients with multi ... Read more >

NCT06122246

Status: Open Not Enrolling

Investigator: Khurram Nasir

Study Coordinator: Zulqarnain Javed

Phone: 346.356.1481

In this comparative effectiveness trial, the aim of this study is to answer the research question of whether a remote blood pressure (BP) management program (RBPM, inclusive of home BP monitoring and telehealth visits with a nurse or pharmacist) ... Read more >

SURTAVI

Status: Open Not Enrolling

Investigator: Neal Kleiman

Study Coordinator: Tia McGaughy

Phone: 346.238.4576

The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgic ... Read more >

The JenaValve ALIGN-AR Pivotal Trial (ALIGN-AR)

Status: Enrolling

Investigator: Michael Reardon

Study Coordinator: Yejide Oyewole

Phone: 346.238.2294

Brief Summary: To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and ... Read more >