To learn more, watch our Intro Video.

The CPRIT RNACore is a key focal point of this support and is funded by a recently renewed multi-year CPRIT grant, as well as industry partnerships.  The RNACore is funded by the State of Texas to facilitate pre-clinical studies in RNA therapeutics; to generate innovative research grade constructs for the scientific community; and to produce RNA therapeutics in our onsite cGMP manufacturing facility for clinical trials.

The Center has invested in the personnel and resources to construct an assembly line to translate RNA discoveries toward the clinic.  The Center is enriched by scientists with skills in RNA construct design, synthesis, purification and validation; a GLP program to generate pre-clinical data for IND submissions; a cGMP team with clean rooms to manufacture clinical grade RNA therapeutics; a first-in-man clinical trials unit; and faculty collaborators in the Department of Nanomedicine who devise customized solutions for RNA delivery. Members of our program are funded by the National Institutes of Health, the US Department of Defense, the Cancer Prevention and Research Institute of Texas (CPRIT) and collaborations with industry partners.

Check Out Our New Brochures

• The Center for RNA Theraputics Brochure
• mRNA therapeutics for Skin Rejuvenation Brochure

Medical Director

John P. Cooke, MD, PhD
Joseph C. “Rusty” Walter and Carole Walter Looke Presidential Distinguished Chair in Cardiovascular Disease Research, Department of Cardiovascular Sciences | Chair, Department of Cardiovascular Sciences | Professor of Cardiovascular Sciences | Director, Center for Cardiovascular Regeneration | Houston Methodist | Weill Cornell Medical College

Administrative Director

Susmitha K. Gadde, MBBS, MBA, CCRP
Research Administrative Director
Center for RNA Therapeutics
Houston Methodist DeBakey Heart and Vascular Center

Education Outreach