Infectious Disease & Pathology Research

At Houston Methodist, our investigators follow many areas of leading-edge infectious disease research — molecular mechanisms of pathogenesis, human genetics of susceptibility to infectious agents, vaccine development, and prevention of hospital-acquired infections— in order to discover innovations that improve clinical practice.  We conduct our research in state-of-the-art facilities using genome-wide analysis methods and high-throughput technologies. Our facilities include a biosafety level 3 laboratory, confocal microscopes, gene expression microarray biochip stations and ABI sequencing capabilities. Our researchers help combat the tremendous toll infectious diseases take on human morbidity and mortality by exploring a diverse range of pathogens, including Streptococcus A and B, Mycobacterium tuberculosis, Staphylococcus aureus and Vibrio cholera, to name a few. 
Flesh-Eating Bacteria Evolution

Houston Methodist scientists have discovered how harmless bacteria can quickly turn into flesh-eating monsters. Learn More.

Rapid TB Screening Nanofilms: nanotraps

Precisely engineered technology uses silica nanopore thin films to isolate Mycobacterium tuberculosis antigens in clinical samples for rapid TB screening. Learn More.

James Musser, MD, PhD

James Musser, MD, PhD, is the Fondren Distinguished Endowed Chair of the Department of Pathology & Genomic Medicine and Professor of Pathology and Genomic Medicine. Learn more.

Virulence Gene Discovery

Researchers report the discovery of a natural gene variant that decreases Group A Strep virulence in infection & immuniy. Learn More.