Clinical Trials

    Showing 1 - 10 of 12 Pain

    A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

    Status: Enrolling

    Investigator: Aparna Kamat

    Study Coordinator: Jaya Kamath

    Phone: 713.441.6616

    Researchers are looking for other ways to treat relapsed high-grade serous ovarian cancer. Relapsed means the cancer came back after treatment. High-grade means the cancer cells grow and spread quickly. Serous means the cancer started in the cells th... Read more >

    A Phase 3 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia (SHASTA-10 Study)

    Status: Open Not Enrolling

    Investigator: Abhishek Kansara

    Study Coordinator:

    Phone:

    This is an open-label study to be conducted in adults with hypertriglyceridemia (HTG) and severe hypertriglyceridemia (SHTG). Each participant must have completed all required visits per protocol in the parent study AROAPOC3-2003 (USA and Canada part... Read more >

    Acupuncture Trial

    Status: Open Not Enrolling

    Investigator: Polly Niravath

    Study Coordinator: Milan Sheth

    Phone: 713.790.3311

    A single arm pilot study of 20 patients will be used to determine the feasibility of EA as a treatment for cancer survivors who have been treated with curative intent, but who have persistent CIPN for ?3 months after the cancer treatment is completed... Read more >

    ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement

    Status: Open Not Enrolling

    Investigator: Neal Kleiman

    Study Coordinator: Sejal Dave

    Phone: 281.654.5383

    Brief Summary: To evaluate safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for transcatheter aortic valve replacement (TAVR) in subjects with severe native aortic stenosis who are indicated for TAVR. Detailed Description: ... Read more >

    CardiolRx in Recurrent Pericarditis Following IL-1 Blocker Cessation (MAVERIC)

    Status: Enrolling

    Investigator: Maan Malahfji

    Study Coordinator: Fareeha Dadabhoy

    Phone: 713.441.2116

    Multi-center, randomized, double-blind, placebo-controlled, phase-3 Trial. Patients with a history of recurrent pericarditis who are being treated with an IL-1 blocker for at least 12 months, scheduled to be discontinued, will be approached for poten... Read more >

    Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

    Status: Enrolling

    Investigator: Neal Kleiman

    Study Coordinator: Deena Victor

    Phone: 713.441.4536

    Brief Summary: To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation (DMR) who have been determined to be at prohibitive risk for mitral valve surgery by ... Read more >

    IMPACT ON SURVIVAL OF FAITH-BASED SPIRITUAL CARE OR PSYCHOTHERAPY COMBINED WITH PALLIATIVE CARE VERSUS PALLIATIVE CARE ALONE IN PATIENTS WITH NON-CURATIVE MALIGNANCIES

    Status: Enrolling

    Investigator: Hanh Mai

    Study Coordinator: Natolie Hamilton

    Phone: 713.441.4203

    This phase III clinical trial will evaluate the impact on survival of adding chaplain-provided spiritual care or psychotherapy/meditation to standard-of-care (SOC) and palliative measures, plus chemotherapy if recommended, and comparing it with SOC a... Read more >

    Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

    Status: Enrolling

    Investigator: Pedro Ramirez

    Study Coordinator: Jaya Kamath

    Phone: 713.441.6616

    This phase III trial compares minimally invasive surgery (MIS) to laparotomy in treating patients with stage IIIC-IV ovarian, primary peritoneal, or fallopian tube cancer who are receiving chemotherapy before and after surgery (neoadjuvant chemothera... Read more >

    NWBT 020221 - DC-Vax

    Status: Open Not Enrolling

    Investigator: David Baskin

    Study Coordinator: Helga Jones

    Phone: 713.363.9388

    " Purpose The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM for whom surgery is indicated. Patients must enter screening at a participating site prior ... Read more >

    Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease (Target CD)

    Status: Enrolling

    Investigator: Malcolm Irani

    Study Coordinator: Melissa Whipple

    Phone: 713.441.3247

    Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most frequently affecting the bowels. It can cause many different symptoms including belly pain, diarrhea, tiredness, and weig... Read more >

    The CompassHER2 Trials (Comprehensive Use of Pathologic Response Assessment to Optimize Therapy in HER2-Positive Breast Cancer) CompassHER2 Residual Disease (RD), a Double-Blinded, Phase III Randomized Trial of T-DM1 Compared With T-DM1 and Tucatinib

    Status: Open Not Enrolling

    Investigator: Kai Sun

    Study Coordinator: Jawairia Jawed

    Phone: 346.356.3603

    This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in patients with high risk, HER2 positive breast cancer. T-DM1 is a monoclonal antibody, called trastuzuma... Read more >

    TRILUMINATE Pivotal Trial

    Status: Open Not Enrolling

    Investigator: Sachin Goel

    Study Coordinator: Padmaja Naik

    Phone: 713.441.7386

    Brief Summary: The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or great... Read more >