CREST-2

Investigator: David Chiu, MD

Study Coordinator: Jason Lee

Status: Enrolling

ClinicalTrials.gov Number: NCT02089217

Phone: 713.394.6479

IRB Number: Pro00012292

Description

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed.
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