Houston Methodist Academic Institute

Sir William Osler, MD, known as the Father of Medicine, once said, “Medicine is a science of uncertainty and the art of probability.”

Every day, Houston Methodist accepts the challenge at the confluence of uncertainty and probability. Our culture, “science in service of health,” has furthered our global collaborative network that transitions proof-of-concept medical research to clinical impact and educates healthcare professionals in the latest medical breakthroughs.

Jenny C. Chang, MB.ChirB., MD, MCHM

Ernest Cockrell, Jr. Presidential Distinguished Chair, Houston Methodist

President and CEO, Houston Methodist Academic Institute

Executive Vice President and Chief Academic Officer, Houston Methodist

883

Faculty With Academic Appointments

$90m

Extramural Funding

1,690

Clinical Studies & Trials

71

GME Programs

Cycle of Translation


A Transformational Vision for Academic Medicine


Translating fundamental discoveries into tangible solutions that benefit the public is fraught with challenges. The most promising innovations have a lifeline at Houston Methodist with support at every step of the cycle of translation, from bridge funding to technical expertise with FDA-approved cGLP and cGMP facilities and clinical trial operations.

 

This process is catalyzed by translational infrastructure that includes intellectual property and regulatory expertise, external partnerships, and funding mechanisms designed to transform patient care. Learn more.

Cycle of Translation

Breakthrough Research

The Power of Translation

At Houston Methodist, fostering innovations with the potential for clinical application is at the very heart of what we do. Our interdisciplinary teams of clinicians and researchers are committed to streamlining the process of translating discoveries into treatments and cures for our patients.
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Explore Our Research
Clinical Trials

Clinical Trials

At Houston Methodist, our deep commitment to finding new ways to prevent and treat illness to improve the health of our patients means that our primary goal is to make a clinical trial available to every person who needs and wants to participate in one. Houston Methodist monitors more than 1,430 clinical protocols and has over 500 active clinical trials.
Clinical Trials
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Research Cores

Accelerating Research

Houston Methodist has built more than 20 core facilities to provide our investigators and external researchers access to exceptional scientific technology. Whether an investigator is in the initial phase of discovery or is developing, testing or validating a new drug or device, the Research Institute has a core facility ready to assist in every step with technical expertise and state-of-the-art equipment.
Our Research Cores
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Our Labs

Leading Medicine

Houston Methodist’s research faculty labs work to rapidly translate discoveries made in laboratories and clinics into new diagnostics, therapies and treatments. Cancer, heart and vascular conditions, radiology, immunobiology, infectious diseases, molecular medicine, nanomedicine, neurosciences, health care performance, regenerative medicine and transplantation are among the research areas our labs are focusing on today.
Our Labs
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Research News
doctor holding a tablet with a chest scan on it's screen
Personalized Treatment Strategies for Lung Cancer
Houston Methodist researchers identified a novel and innovative marker to guide Immune Checkpoint Inhibitor Therapy for Lung Cancer.
woman sitting on an examination table in a doctor's office
Trailblazing New Perspectives: Treating Gynecological Cancers
The goal of this new study was to evaluate the feasibility of a phase three, multi-center randomized clinical trial comparing the efficacy of minimally invasive surgery with that of the traditional open method approach (laparotomy) in treating epithelial ovarian cancer.
arm in blood pressure testing machine
Getting to the Heart of Hypertension Disparities
Researchers address social risk factors for high blood pressure through a national study.
Evolving Treatment Beyond Pharmaceuticals
First-of-its-Kind Study Explores Novel Prescription Digital Therapeutic
An Unusual Presentation of Glioblastoma
Andrew Lee, MD, Herb and Jean Lyman Centennial Chair in Ophthalmology, recently published one of the first-ever reported cases of progressive vision loss as the presenting manifestation of recurrent GBM with secondary LMS to the optic chiasm.
Engaging T cell Exhaustion for Solid Tumor Immunotherapies
Houston Methodist researchers investigated T cell exhaustion in murine models of prostate cancer and melanoma to explore possible advancements in immunotherapies for solid tumors.
Fighting a Deadly Duo
Investigating therapeutics to fight deadly TB/HIV coinfections.
Houston Methodist, Rice University launch groundbreaking Digital Health Institute
This initiative builds on ongoing collaborations between Houston Methodist and Rice University to transform the future of health care.
Stage I Nodal Marginal Zone Lymphoma Treatment Landscape
Houston Methodist researchers compared systemic therapy and radiation therapy in Stage I Nodal Marginal Zone Lymphoma Patients
2024 Digital Health Workshop Seed Fund Award Winners Announced
Houston Methodist researchers and their collaborators from Rice University have been awarded grants from the 2024 PATHS-UP Digital Health Workshop.
Breast Cancer Cells
Nanomedicine Makes Big Strides in the Fight Against Breast Cancer
Researchers deliver immunotherapy directly into triple-negative breast cancer tumors with nanofluidic implants, achieving tunable and sustained dosing of immunotherapeutics with high anti-tumor activity.
headshot of Constance Mobley smiling
Liver Failure Avengers Houston Methodist Researchers First in World
Under the leadership of Constance Mobley, MD, PhD, FACS, researchers have successfully performed a first-in-human miniature liver hepatocyte transplant to change a patient’s lymph nodes into ectopic miniature livers.
Predicting the Future of Cancer Treatment

Houston Methodist faculty developed a multiscale mechanistic model to further investigate the role of miR-155 in non-small cell lung cancer and predict clinical efficacy based on preclinical data.

Taking a Closer Look at West Nile Neuroimaging

A case report reviewing West Nile neuroinvasive disease imaging characteristics and the differential diagnosis of acute leukoencephalopathy highlights the usefulness of neuroimaging in WNND diagnosis in the absence of CSF markers.

Ending Organ Transplant Rejection

Studies at Houston Methodist suggest a novel strategy that may potentially eliminate or diminish transplant rejection, autoimmune diseases, and the need for immunosuppressive drugs

Location, Location, Location is Key to Pancreatic Cancer Prognosis

Molecular alterations found in pancreatic ductal adenocarcinoma samples may have potential therapeutic implications

Innovative Education

Discover the Difference

Houston Methodist Academic Institute provides clinical and translational research education with a patient-centered focus and interprofessional, team-based approach.
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Explore All Programs
GME Programs

GME Programs

Houston Methodist is an extraordinary place, built on our I CARE values of integrity, compassion, accountability, respect and excellence, while always keeping the patient at the center of everything that we do. Houston Methodist offers a wide variety of accredited and non-accredited residency and fellowship programs for physicians who want to pursue subspecialty training.
GME Programs
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Weill Cornell PhD Program

Weill Cornell PhD program

The Weill Cornell Graduate School of Medical Sciences has expanded its PhD program to the Houston Methodist Academic Institute, the research and education arm of Houston Methodist in the Texas Medical Center. This enhancement builds upon the 16+-year academic affiliation between Weill Cornell Medicine and Houston Methodist to train the next generation of physicians and scientists.
Weill Cornell PhD Program
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Advanced Clinical Training

The Bookout Center for Medical Innovation, Technology, Research and Education

The first facility of its kind, MITIE now encompasses 35,000 square feet of research and training space dedicated to procedural skills acquisition and the development of image-guided technology, medical robotics, telementoring and new procedural techniques.
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Education News
digital art of floating screens
High Demand Hidden Careers in Research Administration Takes the Stage at Houston Methodist
Houston Methodist has teamed up with the Greater Gulf Coast Translational Science Alliance and the Bay Area Houston Advanced Technology Consortium (BayTech) to create the High Demand Hidden Careers in research administration internship program.
The New Resistance
Houston Methodist received a T32 training grant to equip the next generation of clinicians and scientists to address antimicrobial resistance and tackle its dire impact on human health.
2024 Cardiovascular Research Foundation® Rankings
DeBakey Center was recognized as part of the 2024 Cardiovascular Research Foundation® Scientific Excellence Top 10 at the 2024 Transcatheter Cardiovascular Therapeutics® Conference.
2024 Summer Internships at Houston Methodist Were a Hit

Houston Methodist welcomes undergraduates and high school students for summer research internships.

Expanding Medical Education to Houston Methodist The Woodlands
An anonymous philanthropic donation of $10 million led to the expansion of academic medical programs at Houston Methodist The Woodlands.
Residency Match Day Event for EnMed Students

Houston Methodist hosted the second Match Day event in March 2024, which successfully matched medical students with residency programs across the nation.

Dr. Cooke and The Wunderkind
Mentoring a New Generation of the Best and Brightest

Upcoming Academic Events

Conference, seminars, grand rounds, tumor boards, regularly scheduled series and case presentations are offered in multiple clinical disciplines and Houston Methodist locations.
Eighth Annual MAPTA Summer Science Symposium
Houston Methodist Research Institute

Aug 01 @ 9AM

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Second Annual Essentials of Obesity Management
Houston Methodist Research Institute

Aug 02 @ 8AM

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19,600

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