Neuroepigenetics Lab

Yi Lan Weng, PhD
Scientist, Research Institute
Center for Neuroregeneration
Department of Neurosurgery
Neurological Institute
Houston Methodist
The Weng lab is interested in understanding how the regenerative capacity is governed in the nervous system. We use combinatorial approaches including next-generation sequencing, molecular biology and fluorescence imaging to study the epitranscriptomic mechanisms in neural repair and human pathologies at different stages of development. In particular, we are interested in the m6A RNA methylation in regulating RNA trafficking, localization and translation, as well as how dysfunction of these mechanisms could be linked to brain disorders. The long-term goal is to use knowledge obtained from these analyses to guide therapeutic approaches for treatment of injuries, stroke and neurodegenerative diseases.