Qin Lab

Lidong Qin, PhD 
Professor of Nanomedicine,
Houston Methodist Academic Institute

Translational cancer medicine is the focus of our research group. In particular, we develop nonconventional technology platforms for cancer diagnosis and risk analysis, measurement of cancer cell mechanical properties and phenotype enrichment, and in vitro models for the study of the cancer cell microenvironment. Our technological expertise includes rational design of microfluidics platforms that allows for rapid and high-throughput molecular and cellular assays, fabrication of bio-inspired microstructures that simulate the cancer cell microenvironment, and development of nanotools that assist molecular signal amplification.

Our biological targets address the cancer metastatic cascade, with focuses on cancer cell phenotype transition in the primary tumor, detection of circulating biomarkers and circulating tumor cells in the blood, and cancer cell migration and invasion at the metastatic site. The combination of our technological strengths and understanding of cancer cell biology has helped us develop several interesting technological innovations and opened many new avenues of future research direction. At the Biomicrofluidics Core, we create custom designed microfluidic molds and chips, fabricate pre-made biomicrofluidic chips, and provide consultation services in the biomicrofluidics field.